Bioinformatics Jobs

SHIFT: Day (United States of America ... Bioinformatics Scientist II – Children’s Hospital of Philadelphia (Philadelphia, PA): Develop and maintain WDL/CWL pipelines for Next Generation Sequencing (NGS) analysis to provide a wide spectrum of testing for genetic conditions, cancer diagnoses and treatments, and histocompatibility and immunogenetics. Develop and implement bioinformatics infrastructures for highly adaptive genetics tests in high-performance computing (HPC) systems. Develop and optimize workflow controls in Apache Airflow to reduce the turnaround time for analysis of clinical samples. Apply machine learning algorithms to profile central nervous system (CNS) tumors using DNA methylation array. Evaluate and optimize NGS pipelines, and collect, create and maintain in-house bioinformatics resources. Utilize different sequencing technologies (e.g., WES, WGS, RNA-seq, cfDNA sequencing) and implement technology specific analysis workflows in clinical diagnostics. Implement the automation process for monitoring workflows and delivering the analysis results and raw data and write standardized procedures for handling exceptions. Maintain internal databases to store analysis data and public/private resources. Develop scripts to perform inhouse filtration, annotation and prioritization of variants which potentially cause diseases. Requires a Bachelor’s degree in any applicable biological or computational discipline, such as Bioinformatics, and 3 years of experience developing high-throughput genomics/genotyping technologies for NGS data analysis and machine language tools using Python/R/JavaScript/WDL/CWL coding and Linux/Unix and FileMaker Pro scripting, as well as experience utilizing bioinformatics tools (e.g., Mutect2, GATK, Picard, BWA, STAR, edgeR, Samtools, VEP, VT, Slivar, Bedtools, IPA), and data from public and private resources (e.g., UCSC, NCBI, gnomAD, HGMD and COSMIC). Telecommuters considered. Apply online at www.chop.edu/careers. VEVRAA Federal Contractor/Seeking priority referrals for protected veterans. Please contact hiring office with any referrals or questions. CHOP Careers Contact: Talent Acquisition Address; 3401 Civic Center Boulevard. Philadelphia, PA 19104. Telephone 866-820-9288. Email: TalentAquisition@email.chop.edu Children’s Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, national or ethnic origin, disability, or protected veteran status

Summary The Therapeutic Innovation Center (THINC) at the Baylor College of... Medicine is seeking exceptional computational biologists interested in pursuing research opportunities in the field of transcriptional biology. Senior Bioinformatics Analyst have a strong quantitative background with expertise in bioinformatics and prior research experience. Knowledge of at least one object-oriented programming language and/or experience with high throughput sequencing data analysis is strongly preferred. Senior Bioinformatics Analyst will be expected to lead computational analysis projects motivated by specific biological hypotheses. Tasks will include development of computational algorithms and pipelines for the analysis of multiple forms of molecular data including RNA sequencing. Job Duties • Interacts with group leaders and center leadership to design overall approaches for the experimental and computational teams. • Drives Independently custom hypothesis-driven analyses to address fundamental questions in gene regulation. • Develops computational and visualization tools and software to enable non-computational scientists to explore and analyze high dimensional data. • Annotates and maintains collaborative computational environments and code bases with an emphasis on reproducibility and rigor. • Maintains a collaborative, collegial and respectful team environment. Minimum Qualifications • Bachelor's degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a related field. • Four years of relevant experience. Preferred Qualifications • Master’s degree in a related field. • Strong quantitative background with expertise in bioinformatics and prior research experience. • Knowledge of at least one object-oriented programming language and/or experience with high throughput sequencing data analysis is strongly desired. • Experience in object-oriented programming (e.g., R or Python). • Experience in Linux/Unix based environments. • Competency in multiple biological key areas that includes molecular biology, genetics, and cancer biology. • Competency in multiple key areas including algorithms, statistics, data visualization, and high-throughput sequencing methodology. Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer. 14281 CA; CH; SN

Overview The Bioinformatics and Computational Biology Program in the Analytics Practice Area at RTI International has an opening for a Bioinformatics Analyst, Middle Career to contribute to development of bioinformatics tools, support and promote data interoperability, and analyze complex data sets. A fundamental understanding of biomedical research data, excellent verbal and written... communication skills, and experience with scripting languages are essential. Residing in the Bioinformatics and Computational Biology Program of the Analytics Practice Area, the Bioinformatics Analyst will have access to colleagues with expertise in genetics, genomics, high performance computing and software engineering to extend their skill set. Most work is accomplished by interdisciplinary teams, promoting innovation and collaboration. These positions will be based in RTP, North Carolina or Fort Collins, CO but telecommuting is an option. Responsibilities • Curate biomedical data • Contribute to the development of bioinformatics tools • Work with colleagues to develop tools and methods to enhance data interoperability• Learn new software and/or programming languages as needed• Contribute to interdisciplinary teams; be a team player Qualifications Required:• Master’s degree in Computer Science, Bioinformatics, Computational Biology or related discipline and 1 years of experience, or Bachelor’s degree with 3 years of relevant experience.• Experience with some of the following is required:• Data management, curation, aggregation, or analysis of biomedical research or clinical data• Web development languages and frameworks, e.g., PHP, .Net, HTML, JavaScript, JSON, jQuery, AJAX, CSS3, Drupal, CakePHP, Bootstrap• Procedural or scripting languages (e.g. R, Python, Perl)• Object oriented languages (e.g., Java, C#)• Development of databases, data management tools, and/or web applications for biomedical data• Working knowledge of bioinformatics tools and resources• UI/UX design • Excellent verbal and written communication skills• To qualify, applicants must be legally authorized to work in the United States and should not now or in the future, require sponsorship for employment visa status. Preferred Experience:• High performance computing and/or cloud computing• Ontology, Semantic Web and Triplestore Database• Common Data Models and data exchange standards• Development of data analysis and/or data visualization tools #LI-KV1 EEO & Pay Equity Statements As a global employer of choice, RTI is committed to equity, diversity, inclusion and belonging in the workplace and the communities and markets where we serve our mission. We value diversity of thought, culture, background and perspective and welcome applicants without regard to race, color, religion, sex, age, marital status, sexual orientation, gender identity, national origin, creed, citizenship status, disability, protected veteran status, or any other classification protected by applicable discrimination laws or RTI policy.We are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. Further information is available here.RTI International is an independent, nonprofit research institute dedicated to improving the human condition. Clients rely on us to answer questions that demand an objective and multidisciplinary approach and one that integrates expertise across the social and laboratory sciences, engineering, and international development. We believe in the promise of science, and we are inspired every day to deliver on that promise for the good of people, communities, and businesses around the world. For more information, visit www.rti.org.For USA Job Postings Only: RTI participates in the US Government E-Verify program. Further information regarding the E-Verify program and laws that are designed to protect you against discrimination relating to your legal right to work in the US can be found here.For San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here. The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer. At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance. Hiring Salary Range $79,000-$98,000

PRINCIPAL SCIENTIST, BIOINFORMATICS CAMBRIDGE, MA (HYBRID... $160,000-$170,000 THE COMPANY This biotech leader is searching for a Principal Scientist, Bioinformatics to join their team. You will be part of a team that is looking to address the underlying cause of diseases. Work closely with the co-founder and collaborative team. Role & Responsibilities: • Develop strategic plans for analyzing NGS data • Build and maintain bioinformatics applications using AWS • Manage and develop a team of computational scientists • Research and propose novel approaches to upregulate gene expression • Implement bioinformatics pipelines to search for new RNA signatures Skills: • PhD in Bioinformatics or Computational Biology • Python • NGS analysis experience (scRNAsq, bulk RNA, WGS) • Deep understanding of RNA splicing and RNA protein binding • Experience developing analytical workflows using snakemake or nextflow • Data visualization experience Benefits: • $160,000-$170,000 • 401k w/company match • Competitive PTO Please apply and send your CV

The Computational Scientist will provide analysis and develop algorithms and software for Professor Wenyi Wang's lab in the Department of Bioinformatics and Computational Biology. Dr. Wang's laboratory performs research aiming to gain new knowledge in the evolution of the human genome as well as the cancer genome. JOB SPECIFIC COMPETENCIES... Pipeline maintanence: Maintains and develops bulk and single-cell DNA, RNA data processing pipelines.. Protocol and agreement management: Maintains and develops research protocols and data access agreements. Software development: Maintains and further develops the lab's software packages, in collaboration with students and postdocs in the lab. Sequencing data analysis: Performs single cell and bulk sequencing data analysis, including data QC and initial processing, for data generated by in-house and by large-scale consortia. Computing management: Manages software and data stored on the lab's partition on the institute's high-performance computing infrastructure. EDUCATION: Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Physics, Applied Mathematics or related field. EXPERIENCE: Required: Five years experience in scientific software development/analysis. With Master's degree, three years experience required. With PhD, one year of experience required. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 151751 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 81,000 • Midpoint Salary: US Dollar (USD) 101,500 • Maximum Salary : US Dollar (USD) 122,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Hybrid Onsite/Remote • Pivotal Position: Yes • Science Jobs: Yes

As part of the new, ambitious, Data Science initiative at MDACC, we are establishing an innovative AI-augmented, Adaptive, Drug Discovery and Development computational Platform to accelerate the discovery and impact of novel therapies for cancer. The Platform will be intelligent and ever-learning. The Platform will enable novel opportunities for optimized therapies for patients with focus on rare... and hard-to-treat cancers through development of novel machine learning and Al technologies. The primary purpose of this Computational Scientist (Bioinformatics) is to carry out data preparation responsibilities; develop skilled bioinformatics and statistical programs; perform statistical analysis; and prepare written reports, manuscripts, and grant applications with investigators; working closely with the team and collaborators to discover novel therapeutic opportunities for cancer patients. Job Compentencies: • Bioinformatics tools and pipelines especially for Whole Genome /Exome sequencing, RNAseq, ideally for both bulk and Single Cell Analysis • Developing bioinformatics pipelines and analysis tools • Unix, R/Matlab, Python • Gene Set Enrichment and pathway analyses • Whole Genome /Exome sequencing, RNAseq data analysis from raw data including evaluating outputs, optimizing parameters and summarizing findings • Results interpretation (variant calling, functional annotation) • Data visualization and biological interpretation • Produce output for scientific publications and co-author said publications • Data clean-up and QC of biological sequencing data • Running bioinformatics pipelines on high performance computing. Other duties as assigned. Service Orientation: 1. Conduct research and interactions with colleagues in a reliable, responsive, safe, friendly and courteous manner. 2. Promotes inclusiveness and collegiality by demonstrating respect and professionalism to others at all times 3. Models safe, ethical behavior, mitigating risk to the institution through sound business practices, and adherence to MD Anderson's Standards of Conduct, institutional policies and procedures 4. Meets time and attendance expectations and responds to requests in a timely manner, communicating expectations for procedures, service arrival, or project deliverables to coworkers 5. Admits when wrong, apologize and take steps to resolve a situation to help to coworkers before being asked. EDUCATION: Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Physics, Applied Mathematics or related field. Preferred: PhD in Natural/Medical sciences or computational biology, ideally with postdoctoral experience EXPERIENCE: Required: Five years experience in scientific software development/analysis. With Master's degree, three years experience required. With PhD, one year of experience required. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 149757 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Day/Evening • Minimum Salary: US Dollar (USD) 81,000 • Midpoint Salary: US Dollar (USD) 101,500 • Maximum Salary : US Dollar (USD) 122,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Hybrid Onsite/Remote • Pivotal Position: Yes • Science Jobs: Yes

Center Information: The Quantitative Biomedical Research Center (QBRC) is a well-established research center in the Department of Population and Data Sciences at the University of Texas Southwestern Medical Center (UTSW). It aims to foster collaborations involving quantitative methods and technologies in any aspect of biomedical research, particularly for understanding disease etiologies and... developing treatment and prevention strategies. We are actively recruiting new members to join this new and dynamic group. Position Title: Assistant Professor Duties & Responsibilities: We are seeking applicants for a faculty position in bioinformatics research in spatially resolved functional genomics. This project aims to adopt cutting-edge spatial molecular profiling techniques for innovative biomedical research. Specifically, we are seeking individuals with solid background in biology with strong interests in bioinformatics analysis. Related websites: QBRC: https://qbrc.swmed.edu/ At UTSW, there are great opportunities for researchers to collaborate with outstanding biomedical investigators and work on exciting research projects. UTSW provides a friendly, dynamic, collaborative, and integrative research and training environment with state-of-the-art facilities. UTSW offers an outstanding collaborative environment for research with world-class basic science and clinical colleagues, excellent benefits, and competitive salaries. Dallas is the ninth largest city by population and one of the most ethnically diverse in the US. As a major urban metroplex, the Dallas-Arlington-Fort Worth region continues to experience rapid population growth, with arts and culture offerings as renowned as the athletic franchises. Requirements: Applicants should hold a doctoral degree in Biomedical sciences, Computer Sciences, Statistics, Biostatistics, Engineering or related field. At least 1-2 years of training or work experience in the related fields. Preferred (but not required): working experience in AI, machine learning, predictive modeling, imaging analysis or digital pathology. Appointment rank will be commensurate with academic accomplishments and experience. Qualified candidates should apply online and upload a cover letter, curriculum vitae, and a written statement that describes your commitment to diversity, equity, and inclusion. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. To learn more, please visit: https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion

The primary purpose of the Research Bioinformatician position is to carry out data preparation responsibilities related to cancer clinical trials, develop skilled statistical programs, perform statistical analysis associated with clinical data and prepare written reports to investigators. In addition, this position prepares statistical considerations for basic trial designs or grants and performs... biostatistical reviews of protocols. KEY FUNCTION: • Statistical Consulting and Collaboration: • Compiles, analyzes and reports statistical data for various projects including, but not limited to manual and computer-aided data abstraction and evaluation, clinical trials, computerized imaging and bioinformatics. • Prepares statistical considerations for basic trial designs and carries out uncomplicated statistical analyses independently, but completes statistical responsibilities for more complex projects with supervision. • Assists faculty in the development of new statistical methodology for measurement and analysis of data. • Applies advanced statistical methods, simulation models, and skilled statistical programming as needed. • Assesses relevant literature as well as existing data, evaluates the quality of data used in reports and assists with preparation and distribution of data for committee and scientific meetings. • Attends project meetings with collaborators with or without supervisor as directed by supervisor. • May present findings at relevant meetings both inside and outside of the institution as requested. • Protocol Review: • Participates in the protocol review process jointly with supervisor. • Statistical Reporting: • Prepares written reports to investigators jointly with supervisor. • May present findings at relevant meetings both inside and outside of the institution as requested. • Other duties as assigned. EDUCATION: Required: Master's degree in Biostatistics, Statistics, Bioinformatics, Mathematics or related field. Preferred: PhD in Biostatistics, Statistics, Bioinformatics, Mathematics or related field. EXPERIENCE: Required: Two years experience with mainframe and/or PC databases, document processing and statistical software such as SAS and S-Plus. With preferred degree, no required experience. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 147658 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 81,000 • Midpoint Salary: US Dollar (USD) 101,500 • Maximum Salary : US Dollar (USD) 122,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Remote (within Texas only) • Pivotal Position: Yes • Science Jobs: Yes

Position Summary Caris Life Sciences is looking for a sharp, driven and goal oriented Bioinformatics Scientist Leader to provide bioinformatics and statistical analysis leadership and support for novel biomarker discovery derived from Caris’ proprietary ADAPT Biotargeting SystemTM. These high-profile roles will work closely with our R&D team and executive management to design experiments and... analyze complex clinical and translational data sets. We are looking for team oriented, hands on experts with a passion for personalized medicine and innovation in statistical and mathematical analyses. Job Responsibilities Develop and maintain statistical analytical tools and bioinformatics pipelines. Conduct analysis on biomarker discovery and clinical diagnostics data. Consult on experiment design and data interpretation for laboratory research. Contribute to design and development of informatics infrastructure. Adhere to coding and documentation standards and manage deliverables for area of responsibility. Required Qualifications PhD in bioinformatics, biostatistics, biomedical engineering, computer science and other related disciplines. Demonstrated track record of success. Solid understanding of principles and analytical methodologies in computational biology and bioinformatics. Hands-on experience of state-of-the-art bioinformatics tools, including NGS and proteomic piplines. Proven ability for developing and maintaining bioinformatics pipelines. Experience in developing database and data-driven applications. Programming skills with Perl, Python, shell scripting and/or Java. Skills in statistical analysis and proficiency with statistical package such as R and SAS. Ability to understand laboratory and clinical data. Conditions of Employment: Individuals must successfully complete pre-employment process, which includes criminal background check, drug screening, and reference verification. Also, individual must be fully vaccinated for COVID-19 by the date of hire to be considered for U.S.-based jobs, if not currently employed by Caris Life Sciences. Preferred Qualifications Familiarity with clinical trial design and clinical data analysis is highly desirable. Proficient verbal and written communication skills. Willingness to share and receive information and ideas from all levels of the organization in order to achieve the desired results. Training All job specific, safety, and compliance training are assigned based on the job functions associated with this employee. This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time. Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability

The Department of Biophysics and the Lyda Hill Department of Bioinformatics (Green Center for Systems Biology) at The University of Texas Southwestern Medical Center invite applications for a jointly appointed tenure-track faculty position, primarily at the level of assistant professor, but other ranks may be considered. Appointment rank will be commensurate with academic accomplishments and... experience. We seek outstanding candidates who work at the interface of super-resolution light microscopy and cryoelectron tomography (cryoET). We are interested in both developers of these cutting-edge technologies and high-end users focused on important, mechanistic questions in biophysics and/or cell biology. Ideal candidates will have experience in both super-resolution light microscopy and cryoelectron microscopy. Successful candidates will benefit from an infrastructure highly conducive to the creation of new methods and approaches. In cryoET, they will have access to a newly purchased Thermo Fisher Aquilos II cryoFIB/SEM equipped with both internal cryo-widefield and external Leica cryo-confocal fluorescence microscopes, as well as two Titan Krios cryoelectron microscopes with direct electron detectors, including one with the latest generation cold field emission gun and Selectris-X energy filter. In light microscopy they will be embedded in a program with an outstanding track record of engineering super-resolution, light-sheet and cleared tissue microscopes that are flexibly designed to address a variety of imaging questions. To this effect the Green Center for Systems Biology houses ~25 isolated microscope development bays equipped with optical tables. The Department of Bioinformatics is responsible for running BioHPC, a high performance computing and storage facility which is equipped with ~1000 CPU and ~120 GPU nodes connected to 50 PB of storage for on premise data analysis. All instruments have direct mounts to this computing infrastructure. Besides offering a home in two vibrant, interactive, and physically neighboring Departments, UTSW has a highly collaborative and inclusive environment encompassing the entire spectrum of basic, translational, and clinical research. Candidates must have a PhD degree in biomedical imaging or a related discipline and relevant work experience. The search committee is particularly interested in candidates who, through their research, teaching, and/or service, will contribute to the diversity and excellence of the academic community. Applicants should submit a curriculum vitae, a concise description of previous research accomplishments and future plans (3 page limit) to https://jobs.utsouthwestern.edu/. Please arrange for referees to send reference letters to BiophysicsSearch@utsouthwestern.edu. The screening of applications will begin December 1, 2021 and continue on a rolling basis until the position is filled. Questions may be emailed to BiophysicsSearch@UTSouthwestern.edu. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. To learn more, please visit: https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion