Bioinformatics Jobs

Description Expected Starting Salary Range: 27.60 - 35.28... SUBFUNCTION DEFINITION: Bioinformatics applies biology, computer science, data science, and statistics to analyze and interpret biological and clinical data. REPRESENTATIVE RESPONSIBILITIES • Management and "wrangling" of genomic data. • Help manage Xenopus genomes and participate in genome annotation and gene nomenclature. • Perform gene orthology and genomic synteny analysis. • Help test newly developed code and provide feedback for developers. • Work with biocurators and developers on the technical specification of new features for the website. • Participate in data analysis and development of new ways to visualize data. • Help manage data exports for public use and data exchange with other databases (e.g., NCBI, UniProt). • Co-author reports and publications and give presentations at national and international meetings and workshops. •Informatics Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in various formats (e.g., flat files, relational and non-relational databases). Collects and records appropriate metadata. Ensures data are securely stored yet highly accessible to authorized users. •Data Analysis Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g., genomic, clinical, imaging, sequencing). Utilizes existing software to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage). Utilizes web-based bioinformatics tools and public/proprietary relational databases. Follows standard operating procedures. Works in collaboration with both technology and scientific teams. •Requirements Gathering Interfaces with clinicians/researchers to collect requirements of basic to moderate complexity including user workflows. Contributes to problem-solving and solution evaluation. •Software Evaluation & Development Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows. Under general supervision, assists with implementation and testing efforts. Effectively communicates the status of all efforts to necessary parties. Utilizes project and time management skills to complete projects within specific timeframes. •Publication Contributes to analyses and publications. Generates reports and figures for publications. Assists with materials for publications and scientific meetings. Works closely with biostaticians on the production of publication and presentation materials. Qualifications EDUCATION/EXPERIENCE Required: •Bachelor's degree in Bioinformatics and Genomics or related degree • 0 - 2 years of work experience in a related job discipline Preferred: • MSc or PhD degree in bioinformatics and genomics. • Experience working with genomic data • Experience with a programming language such Python • Experience with standard bioinformatic tools, analyses, and file formats (Genome Browsers, JBrowse, BLAST, BLAT, multi-sequence alignments, GFF, GTF, etc). • Strong interpersonal and communication skills, including excellent written and spoken English. • Demonstrated experience documenting code, pipelines and workflows • Demonstrated ability to work in a team as well as independently, efficiently (i.e., both quickly and accurately) • Preference will be given to an applicant with: • Experience with other genomic databases • Experience in relational databases, data annotation/biocuration. • Experience in analyzing genomics data, using genome browsers and common bioinformatics tools. • Experience with Git based version control, particularly GitLab, and continuous integration. • Experience in constructing and maintaining bioinformatic pipelines. Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA

The laboratory of Chongzhi Zang at the Center for Public Health Genomics, University of Virginia (UVA) is seeking to fill multiple Postdoctoral Research Associate positions in the broad field of bioinformatics and computational biology. The research program in the lab focuses on developing computational methodologies and designing integrative data science approaches to study chromatin epigenomics... and gene regulation. Current ongoing projects include: multi-omics integration-based algorithm development for transcriptional regulation prediction; model-based algorithm development for single-cell epigenomics and spatial multi-omics data analysis; statistical and computational modeling of phase-separated transcriptional condensation; global epigenetic and transcriptional regulation in T-cell immunity and various human cancer systems, etc. More information on research directions and previous publications can be found at the lab website: zanglab.org. The Zang Lab is well funded by NIH and other agencies. Each postdoctoral scientist in the lab will receive comprehensive and personalized training in research and career development, and will have extensive opportunities for independent and collaborative research. Based at the Center for Public Health Genomics in UVA’s School of Medicine, the lab has established close collaborations with multiple labs both within and outside the university, including departments of Biochemistry and Molecular Genetics, Biomedical Engineering, Statistics, UVA Cancer Center and the new founded School of Data Science, as well as several other universities and research institutes. Requirements 1.A Ph.D. or equivalent degree in any quantitative science, including but not limited to Bioinformatics, Computational Biology, Applied Mathematics, Statistics, Physics, Chemistry, Computer Science, Data Science, Engineering or a related field is required by the start date; 2.Proficient in Python (or C/C++) & R programming; 3.Excellent communication and teamwork skills; 4.Strong quantitative background (e.g., statistical modeling, machine learning, computational or theoretical physics, etc.) or computational genomics experience (e.g., high-throughput sequencing data analysis, etc.); 5.At least one peer-reviewed publication written in English in the previous area of research (not necessarily related to biology) with submitted, accepted or published status at the time of application. The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans and persons with disabilities are strongly encouraged to apply. Application Process All positions are restricted and contingent on the continuation of funding. Please direct any questions or inquiries to zang@virginia.edu. The positions will remain open until filled. For further information regarding the application process, please contact: Rhiannon O'Coin at rmo2r@virginia.edu To apply please visit UVA job board https://uva.wd1.myworkdayjobs.com/UVAJobs, and search for " R0040016". Complete the application and see below for documents to attach. Required Application Materials: • CV • Cover Letter • Contact information for 3 references Please note multiple documents can be submitted in the CV/Resume Box. Applications that do not contain all of the required documents will not receive full consideration. The selected candidate will be required to complete a background check at time of offer per University Policy. COVID Vaccination Requirement and Guidelines Please visit the UVA COVID-19 Job Requirements and Guidelines webpage prior to applying for current information regarding vaccination requirements and guidelines for employment at UVA. The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information

Salary: Bioinformatics Advisor - Remote Chippewa Government Solutions (CGS), a Sault Tribe Inc. (STI) Federal company, is hiring an experienced Bioinformatics Advisor to support the Influenza Division of the Center for Disease Control, in Atlanta, Georgia. The incumbent will provide computational biology support and bioinformatics services to support division laboratory data management and analysis activities. Reports to the Project Manager and Deputy Project Manager. Essential Duties and Responsibilities: • Leads the collection, studies, analysis and management of biological data· Develop experimental methodology for research and data collection· Identify, develop and implement new techniques and technologies for advanced analysis of complex biological data as related to infectious disease research surrounding the disciplines of biological sequence and structural analysis, computational genomics, evolutionary genomics, metagenomics and genome sequencing· Develop scripts and... software for bioinformatics applications (using programming languages such as PERL, BioPERL, java, Ruby, Python)· Plan and develop SQL-based database systems, including NoSQL columnar-based database systems such as Hadoop or Cassandra· May coach and provide guidance to less experienced professionals· Troubleshoots problems • Performs other job-related duties as assigned • Participate in the preparation of information for peer-reviewed journals, scientific conferences and meetings • Create and track the quality metrics for sequencing and variant detection workflows • Develop, in collaboration with other team members, standard operating procedure (SOP) documentation for analytical protocols, script development, and application configuration and development • Identify, develop, and implement software tools • Lead the designing of protocols and processes to automate data analysis as well as perform analysis of complex biological data sets • Responsible for the modeling and visualization of data Supervisory/Management Authority: Position has no supervisory or management authority. Education & Experience: BS, BA, MS or PhD in Biomedical Sciences, Data Analytics, Computer Science, Engineering, Mathematics or other health related field and approximately 8 years of experience Knowledge, Skills, & Abilities: • Previous experience with R, python, JAVA, SQL, Tableau, PERL, Hadoop and Cassandra • Experience with algorithm generation as well as pipeline generation and/or computational methods • Remain up to date on current research applications and methods in the fields of bioinformatics, genomics, metagenomics, virology, and bacteriology in order to provide support for rapid progress of automated data analyses • Proven ability to develop production-quality bioinformatics tools, workflows and applications • Excellent verbal and written communication skills and the ability to express complex technical concepts in business terms Work Environment: Work will be performed in a climate-controlled office setting on a secure government facility. About STI-Federal: Sault Tribe Incorporated (STI) is the independent business arm of the Sault Sainte Marie Tribe of Chippewa Indians. Our mission is to enhance the economy and improve the quality of life for the members of the Sault Sainte Marie Tribe of Chippewa Indians. STI-Federal, the Federal contracting division of STI supports this mission through Exceptional performance in Federal contracts. Benefits: STI offers a competitive benefits package including medical, dental, vision, and life insurance. We also offer 401(k) with 4% employer match, 11 paid Holidays and 15 days Paid Time Off annually. Compliance: Applicants selected will be subject to a U.S. Government security investigation and must meet eligibility applicable clearance level. CGS is a E-Verify Federally Contracted Employer. To ensure compliance with an applicable preliminary nationwide injunction, which may be supplemented, modified, or vacated, depending on the course of ongoing litigation, the Federal Government will take no action to implement or enforce the COVID-19 vaccination requirement pursuant to Executive Order 14043 on Requiring Coronavirus Disease 2019 Vaccination for Federal Employees. Therefore, to the extent a federal job announcement includes the requirement that applicants must be fully vaccinated against COVID-919 pursuant to Executive Order 14043, that requirement does not currently apply. remote work

Overview OMRF is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. Oklahoma City offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy... OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic. Benefits We offer competitive salaries and comprehensive benefits including, medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, paid holidays, onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro and out of state. Learn more about our benefits here. Responsibilities The Nath laboratory is seeking a highly motivated, self-starter senior level scientist with the ability to work with optimal resources and little direct supervision to address important questions in the genetics and genomics of systemic lupus erythematosus (SLE or lupus), an autoimmune disease. Using large-scale genome wise association studies (GWAS), our lab has identified several genes/genetic variants associated with lupus susceptibility. Now we are trying to understand the specific functional effects of those lupus associated genetic variants, using cell lines from patient-derived primary immune cells or tissues. We will apply various modern techniques for studying features of three-dimensional (3D) genomic organization such as 3C, Hi-C, ChIP-Seq, RNA-seq and genome editing using CRISPR/Cas9 based techniques. Successful candidate will be proficient in a wide range of analytical methods and the use of bioinformatics/genetics software for analyzing and interpreting various types of data. Minimum Qualifications Bachelor’s degree in Bioinformatics, Biostatistics, Computer Science, Genetics, Epidemiology, computational sciences or relevant field or a combination of relevant experience and education. Must have knowledge and experience of statistical genetic methods for gene-mapping for complex traits, and computer programming skills (e.g. familiarity with UNIX-like OS, and at least one programming language) are required. Preferred Qualifications Master’s degree in Bioinformatics, Biostatistics, Computer Science, Genetics, Epidemiology, computational sciences or relevant field or Ph.D. in Biostatistics/Bioinformatics desired. The successful applicant is expected to have a strong interest in genetic epidemiology of complex traits and will have experience in both the application/implementation of established methods for genetics association studies, and in methods development

Summary: Under the general supervision... of the Bioinformatics Scientist Department Manager Laboratory Directors and Pathologists and in accordance with established policies and procedures the Bioinformatics Analyst performs independently in the Department of Pathology. The Bioinformatics Analyst will be responsible for analyzing clinical Next Generation Sequencing data contributing to the development of data analysis pipelines and organizing and maintaining databases. Responsibilities: Participates in the daily clinical bioinformatics workflow such as DNA-seq and RNA-seq data analysis. Analyzes the clinical data for the validation of new Next Generation Sequencing tests. Assists with preparation of validation summaries of the new Next Generation Sequencing tests. Assists in developing analysis pipelines for Next Generation Sequencing tests. Evaluates analytical aspects of emerging analysis methods. Assists in the development of databases and webtools. Other information: BASIC KNOWLEDGE: Bachelor s Degree required. Master s Degree in Bioinformatics Computational Biology Computer Science or a related field is preferred. Demonstrates strong scientific understanding of genomics. Demonstrates proficiency in programming and scripting skills (e.g Perl Python or Java). Demonstrates knowledge of DNA-seq and RNA-seq data analysis tools (e.g. BWA GATK STAR Samtools). Demonstrates knowledge of database and webtool development (e.g. SQL HTML CSS Apache). Maintains up-to-date knowledge of bioinformatics data analysis tools Familiarity with CAP/CLIA lab setting is preferred but not required. EXPERIENCE: At least two years of industry or clinical lab experience. Experience in developing computational approaches for cancer genome and/or germline analysis is highly desirable. Excellent teamwork time management and organizational skills. WORK ENVIRONMENT AND PHYSICAL REQUIREMENTS: This position requires the Bioinformatics Analyst to work closely with Bioinformatics Scientists Medical Technologists Management Laboratory Directors and Pathologists. Ability to operate equipment and instruments and to perform all procedures within assigned laboratory section and interpret them for accuracy. Physical and visual dexterity necessary to conduct and interpret analysis. Visual strain is encountered while closely examining data. INDEPENDENT ACTION: Ability to work independently in a fast-paced multidisciplinary environment. Ability to multi-task and work on multiple clinical and developmental projects simultaneously. Analyst functions independently within the department s policies and procedures. Refers specific complex issues to the Bioinformatics Scientist Manager Laboratory Directors or Pathologists when clarification of policies and procedures is required. SUPERVISORY RESPONSIBILITY: None. Lifespan is an Equal Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race color religion sex national origin age ethnicity sexual orientation ancestry genetics gender identity or expression disability protected veteran or marital status. Lifespan is a VEVRAA Federal Contractor. Location: Rhode Island Hospital USA:RI:Providence Work Type: Full Time Shift: Shift 1 Union: Non-Union

Almaden Genomics is a cloud-native bioinformatics platform that accelerates research teams through streamlined, scalable, and interoperable genomic workflows. With a wide selection of biological databases and toolkits coupled with robust version control of modules and pipelines, entire teams can quickly drag, drop, and connect processes to create a simple visual representation of complex... bioinformatics workflow. All that’s left are streamlined genomic workflows that allow research teams to focus on the science. Position Summary: We are seeking a skilled and experienced Bioinformatician to join our dynamic team of engineers. The successful candidate will be responsible for analyzing and interpreting biological data, designing experiments, and developing computational methods to support customer needs. Duties & Responsibilities: • Analyze and interpret complex biological data using computational tools and statistical methods • Design and execute bioinformatics experiments, including genomic sequencing and analysis, transcriptomics, proteomics, and metabolomics • Collaborate with cross-functional teams to provide bioinformatics expertise and support • Present findings and results to research teams and stakeholders • Maintain knowledge of current trends and best practices in bioinformatics Requirements: • PhD or Master's degree in Bioinformatics, Computational Biology, or a related field • 1+ years industry experience in bioinformatics • Demonstrable strong programming skills in languages such as Python • Demonstrable experience developing bioinformatics pipelines • Experience with bioinformatics databases such as NCBI, Ensembl, UCSC Genome Browser, and others • Experience with data analysis and visualizations of large-scale data • Experience with containerized virtual environments such as Docker • Ability to work independently and manage multiple projects simultaneously Desired Skills: • Experience with single cell RNA-seq analyses • Experience building bioinformatic pipelines with a workflow language such as Nextflow, WDL, Snakemake, etc. • Experience with cloud computing platforms such as AWS or Google Cloud • Experience with Jupyter Notebooks If you are a passionate bioinformatician looking to make a tangible impact in the field of genomics, we encourage you to apply and join our dynamic team at Almaden Genomics. Together, let's shape the future of genomic research and medicine. At Almaden Genomics, we value diversity and always treat all employees and job applicants based on merit, qualifications, competence, and talent. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Culture & Benefits: Almaden Genomics has a culture that is a direct representation of our core values: • Do it with integrity • Bring passion • Be bold • Be respectful • Show humility • Take ownership • Have fun We highly value our employees and provide the following benefits: • Opportunity for equity ownership • Flexible PTO • 401K program • Excellent vision, dental and health benefits

Bioinformatics Analyst Interested in building a career in life sciences? An exciting mid-size Pharmaceutical company on the west coast is looking for talented Bioinformatics Analyst! The opportunity is a fully remote, 6 to 12 month contract-to-extend with benefits. There is an Oncology emphasis but all therapeutic backgrounds are encouraged to apply... The Bioinformatics Analyst will be responsible for: · Leading computational biology and data analysis efforts · Partnering with team members to develop robust data analysis pipelines · Communicating strategies and progress to cross-functional management · Integrating and interpreting heterogenous & noisy datasets from ongoing clinical trials The Bioinformatics Analyst should have the following qualifications: · Master's Degree in scientific discipline · Proficiency with R & Python with working knowledge of AWS · Experience with PowerBI, Tableau, or Splunk · 5+ years experience in the Life Sciences Benefits: · Opportunity for growth at an exciting Pharmaceutical company · Fully remote · Competitive pay rate If you are interested in the Bioinformatics Analyst role, then please don’t wait to apply. Please note this role is only offered on a W2 basis through EPM Scientific

SHIFT: Day (United States of America ... Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP’s Commitment to Diversity, Equity, and Inclusion CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. We strongly encourage all candidates of diverse backgrounds and lived experiences to apply. A Brief Overview The Bioinformatics Engineer I position is an entry-level position in the support of computational environments focused on the management, transfer, formatting, and general processing of complex data types associated with genomics and proteomics. Whereas the Bioinformatics Scientist is primarily focused on the outcome of an analysis in terms of the scientific endpoint, the Bioinformatics Engineer is primarily focused on the outcome of an analysis in terms of validity, efficiency, and robustness. The focus of the position is basic systems implementation of data manipulation and analysis pipelines, applications, general hardware configurations, and bioinformatics-specific hardware configurations. Bioinformatics programming activities are also included. The Bioinformatics Engineer I primarily operates in a local environment as opposed to enterprise-level. The position allows for a wide variety of activities described within the job responsibilities and encompasses positions within both research and clinical environments. Activities occur with a high degree of supervision with low latitude for independent judgment. The Bioinformatics Engineer I will be introduced to the concepts of best practices in scripting, pipeline workflow development, hardware and software configurations, change controls, quality, sustainability, and documentation. The Bioinformatics Engineer I is primarily focused on supporting bioinformatics analytical groups and individuals as an engineering resource. What you will do • Computational Environment Development and Optimization (70%): Contribute to the maintenance and development of bioinformatics tool portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provide efficient data management support. • Work with bioinformatics group members to develop functioning pipelines upstream of customized analysis workflows. • Maintain pipelines by staying current with evolving algorithms and standards and incorporating into pipeline • Optimize performance of applications by working with scientific computing and information systems groups to optimize hardware/software parameters • Define and prioritize requirements for pipeline development over time to incorporate new technologies and platforms via functional communication with bioinformatics group members and bioinformatics end users • Identify appropriate open-source and commercial products that serve needs of pipeline and/or customized analyses of end users. • Implement and maintain commercial and open-source software for common bioinformatics and genomics data analysis. • Implement, update and maintain locally stored data resources required for various analysis tasks. • Provide efficient data management support including file transfers, data formatting and manipulation, and basic integration of data from a variety of experimental and reference resources. • Maintain working knowledge of available commercial and openly accessible knowledgebase as they apply to bioinformatics analysis. • Collaboration and Mentorship (10%) • Collaborate primarily with bioinformatics scientist group and equivalents to produce local scale computational environments • Works with both bioinformatics group members and end users/clients to understand specific needs in bioinformatics and end user-specific domains • Attends group and team meetings and contributes primarily factual information regarding processes and approach • Provide ad hoc support and one-on-one and group-based training on key bioinformatics software, features, and workflows • Documentation and Standardization (20%): • Documents all aspects of computational environment parameters, instructions, and SOP's for existing systems and newly implemented systems. • Ensure that all routinely used tools (e.g. those included in shared analysis pipelines) are versioned and managed through a source control system. • Ensure that configuration files that provide parameters to algorithms and analysis software are versioned and managed through a source control system Education Qualifications • Bachelor's Degree Required • Master's Degree biological or computational discipline Preferred Experience Qualifications • At least one (1) year of experience in applied bioinformatics, computational, and genomics/proteomics areas Preferred Skills and Abilities • Strong UNIX/LINUX expertise required. • Experience with R strongly preferred • Experience with Python, Perl, or other languages preferred. • Experience with pipeline or workflow development frameworks preferred. • Experience with data management preferred. • Familiarity with open source and commercial bioinformatics resources and software preferred. • Experience with genomic data analysis preferred. • Experience or knowledge of technologies commonly used in biological labs, such as PCR, cloning, electrophoresis gels, and cell culture preferred. • Knowledge of the working mechanism of microarray, NGS, mass spectrometry, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is preferred. • Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is preferred. • Accountability and attention to timelines. • Excellent organization and communication skills with an emphasis on strong presentation skills • Ability to work in a team environment. To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, professionals working onsite—at any CHOP location, for any portion of time—must be vaccinated for COVID-19. Learn more. CHOP also requires employees who work in patient care buildings to receive an annual influenza vaccine. Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed. EEO / VEVRAA Federal Contractor | Tobacco Statement

HOW MIGHT YOU DEFY IMAGINATION? You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10... million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role. Scientist – RNA Bioinformatics LIVE WHAT YOU WILL DO Let’s do this. Let’s change the world. We are actively seeking a highly qualified and motivated Scientist with a strong background in RNA bioinformatics. The scientist will join the Bioinformatics Technology team within Amgen’s Center for Research Acceleration by Digital Innovation (CRADI). CRADI is a multi-disciplinary effort embedded within our drug discovery engine that continually uses advancement in digital technologies for disease modeling and digital modality engineering to accelerate our pipeline from target inception through drug development. Bioinformatics Technologies plays a pivotal role within CRADI’s Computational Biology and Bioinformatics function, establishing an innovation engine for deploying and exploiting emerging digital technologies in the field of computational biology. RNA therapeutics comprise a rapidly expanding class of modalities that will fast-track solutions to the clinic. In this vital role you will lead the development and implementation of AI/ML models and optimization paradigms for the design of best-in-class RNA therapeutics. This position will involve close collaborative relationships with scientists within RNA therapeutic research, safety sciences, and therapeutic areas as well as data scientists and engineering partners across Amgen R&D. An ability to communicate clearly and collaborate effectively with colleagues from different fields will be essential. The successful candidate will possess strong analytical proficiency, have a high degree of technical competency in computational sciences with a deep theoretical understanding of machine learning paired with excellent understanding of RNA biology proven by a strong track record of innovative and collaborative research published through peer-reviewed publications. RESPONSIBILITIES: • Engage in collaborative efforts with stakeholders and subject matter experts to formulate technical solutions accelerating the development and increasing clinical efficacy of RNA therapeutic modalities • Find opportunities, set strategy, and deliver appropriate quantitative methods, such as discriminative and generative AI/ML models, to push the state of the art for optimizing RNA therapeutic modality design, formulation, and delivery • Consult on data generation and translate experimental findings into computational model design and refinement • Serve as subject matter expert on the intersection of computer science and RNA biology • Clearly document methods and analyses to allow reproducible research • Collaborate with engineers and data scientists to develop innovative bioinformatics tools that facilitate data access, model utilization, and output interpretation • Communicate project results and data-driven recommendations to stakeholders and cross-functional partners • Monitor, review, and critically interpret published computational research spanning RNA therapeutics and emerging oligonucleotide modalities • Proactively scope and deploy novel computational methods and digital technologies WIN WHAT WE EXPECT OF YOU We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications. BASIC QUALIFICATIONS: Doctorate degree Or Master’s degree and 4 years of computational biology, bioinformatics, biomedical data science or related field Or Bachelor’s degree and 6 years of computational biology, bioinformatics, biomedical data science or related field PREFERRED QUALIFICATIONS: • PhD in computer science, data science, computational biology or bioinformatics including industry experience • Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods • Knowledge in RNA biology, particularly RNA structure and function • Fluency in scientific programming and tool development with R, Python, or equivalents. Proficiency in C++ or Java is a plus. • Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications • Experience with software development good practices, including code versioning, documentation, and testing, amongst others • Experience with cloud computing • Creative, open-minded, and passionate about scientific research • Demonstrated ability to thrive in a team environment • Strong interpersonal, collaborative, organizational, and presentation skills • Understanding of RNA therapeutic modality discovery and development is a plus THRIVE WHAT YOU CAN EXPECT OF US As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The annual base salary range for this opportunity in the U.S. is $135,563 – $150,625. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan • Stock-based long-term incentives • Award-winning time-off plans and bi-annual company-wide shutdowns • Flexible work models, including remote work arrangements, where possible APPLY NOW FOR A CAREER THAT DEFIES IMAGINATION Objects in your future are closer than they appear. Join us. CAREERS.AMGEN.COM Join Us If you’re seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you’ll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancers, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation

The Center for Public Health Genomics at the University of Virginia is looking to hire a Research Scientist. The Research Scientist will be responsible for working with the PI, Dr. Chongzhi Zang, and members in the lab to develop bioinformatics methods and to use integrative computational genomics approaches for studying epigenetics and transcriptional regulation in mammalian model cell systems... and human cancer. Projects will be performed in collaboration with basic and translational faculty in the Department of Biochemistry and Molecular Genetics. Dr. Yuh Hwa Wang’s laboratory is interested in the structure and function of unusual DNA sequences in living cells , and how these sequences cause genome instability and lead to human diseases. Dr. Garrett-Bakelman’s laboratory focuses on the use of functional genomics analyses and experiments to study biological mechanisms leading to Acute Myeloid Leukemia. The job responsibilities include: 1. conducting basic science research using existing and innovative computational biology approaches; 2. developing and maintaining bioinformatics tools used for computational biology research; 3. writing reports and manuscripts for peer-reviewed publications; 4. attending academic conferences (virtually and/or in-person) to present the research works; 5. mentoring and supervising trainees, including postdoctoral fellows, graduate and undergraduate students in the lab on computational biology research; 6. other research related work for the lab. Requirements: 1. Ph.D. or equivalent degree in quantitative science, such as bioinformatics, computational biology, computer science, statistics, applied mathematics, physics, data science, or a related field. 2. At least three-year research experience after completing the doctoral degree on computational epigenomics and high-throughput sequencing analysis. 3. Proficient in Python and R programming. 4. Working knowledge of molecular biology and genomics. 5. Strong academic communication skills and teamwork skills. 6. At least three first-author or senior-author publications in peer-reviewed journals in the related research field. To apply please visit UVA job board https://uva.wd1.myworkdayjobs.com/UVAJobs , and search for "R0025615" Complete the application and see below for documents to attach. Please note that multiple documents can be uploaded in the CV/Resume box. Required Application Materials: • CV • Cover Letter • Contact information for 3 references The selected candidate will be required to complete a background check at time of offer per University Policy. COVID Vaccination Requirement and Guidelines Please visitthe UVA COVID-19 Job Requirements and Guidelines webpageprior to applying for current information regarding vaccination requirementsandguidelines for employment at UVA. The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information