Bioinformatics Jobs

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of... those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contributes to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Position Summary The visiting scientist will be responsible for assisting in the development of a new training paradigm for large language models applied to single-cell RNA sequencing data. This will involve exploiting invariances in the representation of single-cell data to augment the performance and reliability of Geneformers. Geneformers are large language models trained on over 30 million samples of single-cell transcriptomic data, which can be fine-tuned and trained to perform various downstream tasks, including cell identification and in-silico perturbation experiments. In this position you will work with a team of experts in both Machine Learning and Computational Biology. You will have the opportunity to explore the application of advanced ML techniques to drug discovery, gain knowledge of the drug development pipeline, and learn advanced ML techniques. Key Responsibilities • Developing routines to augment single cell data. • Train large language models on multi-Node, multi-GPU clusters. • Benchmark your results against the existing approach. • Prepare a presentation with the results. Qualifications & Experience • Experience in training large deep learning models. • Knowledge about Transformers and other deep learning architectures for natural language processing. • Preferable experience in training large language models. Why You Should Apply Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. BMSEC BMSINTERN BMSCO-OP If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Ginkgo Bioworks is a publicly traded (NYSE: $DNA), high-growth biotechnology company... based in Boston’s Seaport District, that is redesigning the living world to solve some of the globe’s growing challenges in health, energy, food, material, and more. Our mission to “make biology easier to engineer” is poised to disrupt multiple industries by leveraging our innovative data, automation, and scale capabilities in biological engineering. Ginkgo believes that if we are to grow a thriving, sustainable bioeconomy, we must also grow a new market in biosecurity. Our biosecurity and public health initiative, Concentric by Ginkgo, launched a nationwide emergency response to the COVID-19 pandemic, providing end-to-end pathogen monitoring services to schools, communities, and travelers. As we continue to scale Concentric, our work is also evolving into new and exciting directions, from global expansion to the integration of new technologies and capabilities, including our Traveler-Based Genomic Surveillance Plan with the CDC. We are seeking a motivated Bioinformatics Engineer/Test Engineer 2/3 to join our growing Biosecurity Team and be a part of implementing innovative biosecurity solutions. Your responsibilities will include engineering pipelines, analyzing sequencing data, and supporting the development of long-term biosecurity initiatives. In this role you will interface with key teams in the Ginkgo Bioworks Foundry and Biosecurity Divisions to ensure program success through high quality deliverables and innovative offerings. You bring subject matter expertise in bioinformatics, pipeline development, and high performance computing to help the Biosecurity Division’s growing bioinformatics programs; you are a cross-functional team player, bringing diverse perspectives to our interdisciplinary team, and poised to develop the future of biosecurity. Responsibilities • Support Ginkgo’s Biosecurity Teams with your technical expertise in bioinformatics • Design, build, test, deploy, and maintain bioinformatics pipelines • Interface with software engineers to create and implement NGS data analysis pipelines for production use • Collaborate cross-functionally with wet and dry-lab operators on experimental design and analysis to optimize new analytic approaches using NGS technologies • Effectively communicate scientific results to technical and non-technical audiences • Assist with shaping Ginkgo and Concentric’s overall direction as a company and support its evolving needs, as necessary Minimum Requirements • BS with 4+years OR MS with 2+ years OR PhD with 1+ year of experience • 2 years of relevant industry experience is required • Proficient in at least one software programming language (Python) • Proficient in workflow management software (Nextflow, Docker) • Proficient in pipeline development on AWS infrastructure • Proficient in best practices for collaborative software development (GitHub, version control systems, CI/CD, test-driven development, and good documentation habits) • First-hand technical experience in at least two of the following disciplines: bioinformatics, computer science, mathematics, genome assembly & annotation, statistics, probabilistic modeling, machine learning, or quantitative modeling of biological systems • Demonstrated ability to meet the demands of multiple concurrent projects, and work efficiently in a fast-paced, high-growth environment • Ability to adapt to changing priorities and pivot as needed in a fast-paced environment • Superb communication skills, with the ability to effectively convey project plans and complex technical details to a wide range of internal teams, executive leadership, and external customers • Strong curiosity for, and comfort working in, areas of biology & biosecurity previously unknown to you (and, at times, unknown to your peers) Preferred Capabilities And Experience • Experience analyzing and benchmarking outputs from multiple sequencing technologies: Illumina, Oxford Nanopore, PacBio, Hi-C • Direct sequencing and bioinformatics experience with varied pathogen types (e.g. viral, bacterial, fungal) or engineered organisms • Experience with many or all of the following: Python, bash/unix scripting, Snakemake, Nextflow, airflow, CWL, relational databases (SQL), GraphQL, distributed computing (AWS/Google Cloud), Docker, software version control (git) • Data and Database Management: SQL, AWS, Snowflake • Technical program management skills, JIRA, SCRUM, and agile methodologies Total compensation for this role is market driven, with a starting salary of $110k+, as well as company stock awards. Base pay is ultimately determined based on a candidate's skills, expertise, and experience. We also offer a comprehensive benefits package including medical, dental & vision coverage, health spending accounts, voluntary benefits, leave of absence policies, Employee Assistance Program, 401(k) program with employer contribution, 8 paid holidays in addition to a full-week winter shutdown and unlimited Paid Time Off policy. To learn more about Ginkgo, visit www.ginkgobioworks.com/press/ or check out some curated press below: • What is it really like to take your company public via a SPAC? One Boston biotech shares its journey (Fortune) • Ginkgo Bioworks resizes the definition of going big in biotech, raising $2.5B in a record SPAC deal that weighs in with a whopping $15B-plus valuation (Endpoints News) • Ginkgo Bioworks CEO on scaling up Covid-19 testing: ‘If we try, we can win’ (CNBC) • Ginkgo raises $70 million to ramp up COVID-19 testing for employers, universities (Boston Globe) • Ginkgo Bioworks Redirects Its Biotech Platform to Coronavirus (Wall Street Journal) • Ginkgo Bioworks Provides Support on Process Optimization to Moderna for COVID-19 Response (PRNewswire) • The Life Factory: Synthetic Organisms From This $1.4 Billion Startup Will Revolutionize Manufacturing (Forbes) • Synthetic Bio Pioneer Ginkgo Raises $290 Million in New Funding (Bloomberg) • Ginkgo Bioworks raises $350 million fund for biotech spinouts (Reuters) • Can This Company Convince You to Love GMOs? (The Atlantic) We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life. We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology. It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees, employment applicants, and EOE disability/vet. Privacy Notice I understand that I am applying for employment with Ginkgo Bioworks and am being asked to provide information in connection with my application. I further understand that Ginkgo gathers this information through a third-party service provider and that Ginkgo may also use other service providers to assist in the application process. Ginkgo may share my information with such third-party service providers in connection with my application and for the start of employment. Ginkgo will treat my information in accordance with Ginkgo's Privacy Policy. By submitting this job application, I am acknowledging that I have reviewed and agree to Ginkgo's Privacy Policy as well as the privacy policies of the third-party service providers used by Ginkgo's associated with the application process

The Lead/Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development with a focus on the Genomics data. Provides bioinformatics analysis for investigators and communicates analytical process and results. The Genomics Group from the Center for Applied... Bioinformatics at St. Jude Children's Research Hospital is looking for a highly motivated and creative Senior Bioinformatics Research Scientist or Bioinformatic Research Scientist to develop and apply innovative analytical approaches to understand the underlying mechanisms that drive pediatric cancers and other human diseases. Working for all different projects together with different PIs, employee could make a valuable difference not only to science but also to pediatric cancer patient curation and survival. Besides the various analysis tasks, we also encourage exploring newly available methods, pipeline development could result in first author, high profile publications, as long as it aligns with our ultimate goal: “Finding cures. Saving children”. The Center provides a highly interactive environment with collaborative opportunities within the centers including transcriptomics group, genomics group, and genetics group, and across basic and clinical departments, access to high-performance computing clusters, cloud computing environment, novel sequencing platforms such as long reads sequencing technologies, single-cell sequencing at both DNA and RNA level and spatial transcriptomics, innovative visualization tools, highly automated analytical pipelines powered by GPU technology and mentorship from scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The members of this Center could work on broad areas of bioinformatics and gain valuable experiences. The members of this Center also have the opportunity to publish high-profile papers with prominent authorship and file patents for novel biomarker discoveries or novel methods for clinical diagnosis or disease treatment. Good candidates will have experience in building and optimizing analysis workflows using publicly available software/pipelines for high-throughput next-generation sequence data analysis (such as whole-genome sequencing, whole-exome, targeted sequencing and so on) under Linux/Unix environment. The successful candidate is expected to have good programming skills in Bash, Python, and R. Experience with cancer genomics is a plus. St. Jude has been frequently made up to Great Place to Work list such as in Fortune magazine’s “Best Workplaces in Health Care & Biopharma™ 2020” list and GlassDoor's "BEST PLACES TO WORK 2023" list. Salary is highly competitive (comparable to industry) and employee benefits are outstanding. This position is located at Memphis, TN, and relocation assistance is available. Responsibilities • Specific responsibilities may involve NGS data quality control, integrative analyses, data visualization, developing and evaluating analytic tools • Excellent communication skills are essential • You will work closely with St. Jude PIs to provide standardized/customized analysis, using St. Jude high-performance computing clusters or a cloud computing environment Minimum Requirements • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Lead Bioinformatic Research Scientist • Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Senior Bioinformatics Research Scientist • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred Bioinformatics Research Scientist • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with Python preferred Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Payroll Title: BIOINFORMATICS PROGR 1 Department: MEDICINE/Cardiology Hiring Pay Scale... $25.67 - $33.00 / Hour Worksite: Campus Appointment Type: Career Appointment Percent: 100% Union: Uncovered Total Openings: 1 Work Schedule: Days, 8 hrs/day, Mon - Fri #125271 Bioinformatics Programmer I Initial Review Date: Wed 9/27/2023 Apply Now UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply. UCSD Layoff from Career Appointment: Apply by 09/15/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 09/27/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will remain open until a successful candidate has been identified. DESCRIPTION The Department of Medicine (DOM) is the largest department within the UCSD School of Medicine and is responsible for fulfilling the teaching, research, and clinical missions of the University of California, San Diego School of Medicine. The department employs approximately 500 salaried faculty, 168 academic appointees, 331 residents, fellow and postdocs and 479 staff personnel. Computational biologist. Resolves routine programming problems, applying established data processing algorithms to novel data. Works on issues and projects of limited scope. Follows standard programming procedures to analyze situations and data from which answers can be readily obtained. Maintains repositories of published code and answers outside user requests. Aids in the publications of research results. Proficiency in Python, R, Linux, and git version control systems required. AWS experience is a plus. Understanding of major biological data types (genomic SNPs, single-cell RNA-seq expression, protein-protein interaction networks, ATAC-seq, Chip-seq) is required. Will design and develop bioinformatic programs and pipelines to process genomics data. Responsible for lab computer and software maintenance and coordination with other computer facilities. Under direct supervision, applies professional bioinformatics concepts and computational procedures to complete small projects or portions of projects. Works on assignments of limited scope and complexity. Follows standard programming procedures to analyze situations and data from which answers can be readily obtained. MINIMUM QUALIFICATIONS • Four (4) years of related experience, education/training, OR a Bachelor's degree in bioinformatics, biological science, computational / programming, or related area and /or equivalent experience/training. • Basic knowledge of bioinformatics methods, techniques, and data structures. • Programming experience: R, Python, Linux, bash scripting, git version control systems. • Demonstrated experience in processing and analyzing genomics data. • Proven knowledge of applications programming and web development. • Knowledge of modern biology and applicable field of research. Theoretical knowledge in molecular, cellular, or developmental biology. • Effective interpersonal skills in order to work with both technical and non-technical personnel at various levels in the organization. • Strong ability to communicate technical information in a clear and concise manner. • Basic knowledge of application and data security concepts. PREFERRED QUALIFICATIONS • Knowledge of AWS, Jupyter Notebook, HPC • Knowledge relating to the design development, modification and implementation of software including object-oriented programming concepts. • Understanding of major biological data types (genomic SNPs, RNA-seq expression, protein-protein interaction networks. • Experience analyzing singlecell and spatial transcriptomics data. SPECIAL CONDITIONS • Employment is subject to a criminal background check. Pay Transparency Act Annual Full Pay Range: $53,600 - $111,600 (will be prorated if the appointment percentage is less than 100%) Hourly Equivalent: $25.67 - $53.45 Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable). Apply Now If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements. If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable. UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team! Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached. To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community. UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information. UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening

A career at Resilience is more than just a job – it’s an opportunity to change the future. Resilience is a technology-focused biomanufacturing company that’s changing the way medicine is made. We’re building a sustainable network of high-tech, end-to-end manufacturing solutions to better withstand disruptive events, serve scientific discovery, and reach those in need... For more information, please visit www.resilience.com RESILIENCE (National Resilience, Inc.) is a first-of-its-kind manufacturing and technology company dedicated to broadening access to complex medicines and protecting biopharmaceutical supply chains against disruption. Founded in 2020, the company is building a sustainable network of high-tech, end-to-end manufacturing solutions to ensure the medicines of today and tomorrow can be made quickly, safely, and at scale. RESILIENCE will offer the highest quality and regulatory capabilities, and flexible and adaptive facilities to serve partners of all sizes. By continuously advancing the science of biopharmaceutical manufacturing and development, RESILIENCE frees partners to focus on the discoveries that improve patients’ lives. For more information, visit www.resilience.com The Senior Bioinformatics Scientist will play a critical role in the development of state-of-the-art assays, bioinformatics analysis, and workflows applied to cell and gene therapy. This position is essential for advancing the Research, Development, and Manufacturing initiatives throughout the entire Resilience network. With the growing emphasis on next-generation sequencing (NGS) techniques for actionable insights, this role is vital to the success of multiple key projects, including in the development of assays applied to cell and gene therapies as well as engineering better manufacturing systems. Job Responsibilities • Collaborate closely with multi-disciplinary teams consisting of assay scientists, bioengineers, synthetic biologists, software engineers, and data scientists, among others. • Design and implement NGS-centric experiments, analysis, workflows, and data pipelines to meet the analytical requirements of the research and development programs. • Prepare and present technical reports and research findings to stakeholders, including senior management and external collaborators. • Contribute to scientific publications and participate in relevant conferences to share research outcomes and network with peers in the industry. • Drive innovation, keeping on top of the latest advancements in the fields of bioinformatics and engineering, and proactively identify opportunities to apply these innovations within Resilience. Minimum Qualifications • Proven expertise in leveraging bioinformatics for assay development towards research and clinical applications, with a focus on metagenomics, meta-transcriptomics, and clinical microbiology. • Extensive, demonstrable experience in analyzing large and complex NGS datasets (RNASeq, variant calling, alignment, denovo assembly, single-cell technologies) for assay development, research, and/or clinical settings using short and long-read sequencing technologies. • Excellent understanding of microorganism databases and toolkits, preferably related to clinical applications. • Proficient in an object-oriented programming language like Python and/or functional programming languages like R and relevant packages. • Ability to communicate effectively and professionally across various technical disciplines with multiple stakeholders, including management, peers, customers, and suppliers. • Good organizational skills, with the ability to contribute to multiple fast-paced projects simultaneously. Preferred Qualifications • MSc. or PhD in Bioinformatics, Computational Biology, Genomics, Microbiology, or related field. Typically expected industry experience of more than 5 years for a Senior/Staff Scientist with an MSc and 3 years with a PhD. • Experience with GxP or clinical assays in healthcare settings and infection control is a plus. • Experience in collaborating with external research groups and taking part in consortium efforts. • Experience with strain engineering data analysis is a plus. • Experience in Agile and/or Product Development Process (PDP). Resilience is an Equal Employment Opportunity Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, disability status, physical or mental disability, genetic information, or characteristic, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state, and local laws. Requests for reasonable accommodation can be made at any stage of the recruitment process. Resilience offers employees a robust total rewards program including equity, an annual cash bonus program, a 401(k) plan with a generous company match and our benefits package which is thoughtfully designed to support our employees with great healthcare (including medical, dental and vision), family building benefits, life and disability insurance, flexible time off, paid holidays, other paid leaves of absence, tuition reimbursement and support for caregiving needs. Our target annualized base pay hiring range for this position is $140,000.00 - $185,000.00. Actual base pay is dependent upon a number of factors, including but not limited to, the candidate’s geographical location, relevant experience, qualifications, skills and knowledge. Excited about Resilience and the biomanufacturing revolution? We encourage you to apply and start a conversation with one of our recruiters

The Molecular Profiling and Data Science Department at Regeneron is looking for an enthusiastic and motivated Computational Scientist who values independent research in an open and collaborative work environment. You will lead bioinformatic analyses and computational methods development that help the Regeneron Genetics Medicines group create next generation therapies in gene editing, gene... suppression, gene expression, and gene insertion. You will work on projects that use pioneering technologies like AAVs, shRNAs, siRNAs, LNPs, and CRISPR-Cas9 to treat or cure diseases. You will analyze RNA-seq and other omics data to characterize and further develop our therapies. Our department consists of computational scientists with backgrounds ranging from genomics to machine learning, as well as wet-lab NGS technology developers with plenty of sequencing capacity. Beyond our group, you will collaborate closely with scientists in Regeneron Genetics Medicines and other departments to create genetic therapies in a wide range of disease areas, including hemophilia, lysosomal storage disorders, and metabolic diseases, that directly impact the lives of patients. As a Sr. Scientist, Bioinformatics, a day might include the following: • Analyzing RNA-seq data to characterize the natural immunological response to viral and non-viral genetic medicines and develop new immunomodulatory therapeutics. • Investigating the on-target and off-target effects of genetic medicines on gene expression. • Developing new bioinformatic methods to analyze NGS reads to characterize, improve, or limit the endogenous modification and processing of genetic medicines. • Building tools to characterize RNA transcripts and splicing using long-read sequencing. • Collaborating extensively with wet-lab biologists to propose and design the best experiments and NGS readouts. • Contributing to regulatory submissions. • Publishing and presenting novel findings in patents, conferences, and peer-reviewed journals. This job might be for you if: • Want to contribute to the advancement and design of next generation genetic therapies and help shape computational tools used by a rapidly growing part of the company. • Have a strong computational background and enjoy technology development and creating new methods. • Like working at the interface between computation and experiments. • Like diving deep into data, including analyzing raw NGS reads. • Have a curious approach, pay strong attention to detail, and challenge conventional wisdom. • Can effectively communicate with collaborators from various backgrounds and value teamwork. • Want opportunities to showcase and publish your work. To be considered for this role, you must have a PhD degree in Computational Biology, Systems Biology, Quantitative Biology, Bioinformatics, Computer Science, Applied Mathematics, Bioengineering, or related quantitative fields. Experience with bioinformatics analysis at the gene or sequence level,. Proven experience with developing new computational methods, and a strong background (3+ years) in R and/or Python. Previous experience or familiarity with experimental wet-lab molecular biology is highly desirable. Familiarity with a Linux environment, shell scripting, and high-performance computing clusters is a plus. Experience with machine learning on biological problems is also valued. #RGM #LI-Hybrid Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need. The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location. Salary Range (annually) $103,600.00 - $169,000.00

SOPHiA GENETICS combines deep expertise in life sciences with mathematical capabilities in data computing to create the future of AI-assisted Medicine. As we pass 1,000,000 genomic profiles analyzed and look to the future of our platform, we are now searching for a Bioinformatics Customer Service Specialist to join our exciting international team and be at the forefront of scientific and... technological advancements. SOPHiA GENETICS (NASDAQ: SOPH) combines Data-Driven Medicine, Genomics and Radiomics, to ensure that the data used to help patients today will also benefit the patients of tomorrow. SOPHiA DDM™ Platform in supporting multimodal data-driven medicine. The Bioinformatics Customer Service Specialist will report to the Customer Support Level 2 Manager and will be mainly responsible for managing customer cases, guiding customers to success with core bioinformatics workflows, analyzing client data, and creating and updating support documentation. They will work closely with the Bioinformatics Services team to train and share knowledge to improve the resolve rate and resolution time of BioIT client support cases. Main Responsibilities • Answer bioinformatics related questions (internally and externally); • Provide and document resolutions to issues and questions; • Provide BioIT related support to clients including: Performing initial analysis of client data for investigations, answering client BioIT related questions from FAQs and knowledge base, attempt to view and simulate errors by gaining access to client accounts, escalate complex issues to Level 3 support teams as needed and follow up to ensure questions are being promptly addressed, identify similar client issues and request and participate in Root Cause Analysis (RCA) as needed; • Create and update support documentation. • Help with the release cycle: prepare and test new products (pipelines, new gene panels, etc.) for release, set up and run non-regression tests, test new developments and tools • Gather and document customer feedback and collaborate with Data Science and Software Engineering teams to improve SOPHiA GENETICS products and documentation • Mentor and train other members of the support team • As this is a new role within SOPHiA GENETICS, help to define and document other responsibilities. Requirements • Minimum Master’s degree in Bioinformatics, Computer Biology or related field plus 3-4 years’ experience. a PhD degree in Bioinformatics, Computer Biology or related field would be strongly appreciated. • Experience with high performance computing clusters, bioinformatic analysis pipelines, version control systems, and parallel computing. • Proficient in one or more scripting languages (R, Python, Perl, …) • Proficiency in working with Linux, bash scripting, and command line interface • Broad knowledge of NGS data analysis, tools, and methods • Demonstrated understanding of statistics • Experience with handling / manipulating large datasets • Experience parsing CSVs, JSON documents, SQL tables, and making API calls is highly preferred • General knowledge of Microsoft Azure Cloud Services (architecture, technologies, SaaS) Other requirements • Strong interpersonal, written and oral communication skills including the ability to confidently present proposals • Excellent time management, particularly the ability to effectively prioritize and execute tasks in line with business objectives • Customer Oriented • Excellent English verbal and writing skills. Any additional language is a plus Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we drive exponential growth. Business recognition and accolades include: • World's most innovative companies (Top 10) • World's smartest companies (Top 50) • 100 Best Places to Work in Boston • Top 10 European Tech Startup - 2020 • Top 10 European biotechs startup to watch - 2021 • Top 25 East-Coast Biotech to watch - 2021 Plus, you will find : • A flexible, friendly, and international working environment with a collaborative atmosphere • Flexible working hours, including hybrid remote / on-site working model • An exciting company mission that brings together science and technology to directly impact the lives of patients with life threatening illness. • A fast-growing company with plenty of opportunity for personal growth and development • A hard technical challenge to solve with exciting modern technology - cloud computing, Big Data, DevOps, machine learning Location: Boston, USA. Office-based, including 2 days per week remote / 3 days on-site. Start: ASAP (or as agreed) Contract type: Permanent, full-time Application process If you think you fit this position, please send a resume and a cover letter. Please note that incomplete applications will not be considered. After an initial screening process, candidates will be invited for remote interviews

Description Expected Starting Salary Range: 33.97 - 42.86... SUBFUNCTION DEFINITION: Are you passionate about bridging the gap between biology and data analysis? Do you thrive in a collaborative research environment, excited to unravel the mysteries hidden within complex biological data? We are seeking a dedicated and innovative Senior Bioinformatics analyst to join our Bioinformatics Collaborative Services (BCS) team at Cincinnati Children's Hospital Medical Center. In this role, you will play a pivotal role in analyzing and interpreting intricate biological data to derive meaningful patterns across a diverse range of -omics data types, including proteomics, transcriptomics, genetics, and epigenetics. REPRESENTATIVE RESPONSIBILITIES What You'll Do: As a Senior Bioinformatics analyst, you will bring your strong conceptual and practical knowledge to the table. You'll work collaboratively with moderate guidance and supervision, applying your experience in analyzing RNA-seq, ATAC-seq, ChIP-seq, WGS datasets. Key Responsibilities: • Provide bioinformatics insight and support to research labs: collaborate with scientists to design informatic experiments and analyze and interpret complex biological data. • Perform in-depth analysis of diverse -omics data types; proteomics, transcriptomics, genetics, and epigenetics. • Maintain documentation of analysis work including upkeep of a detailed lab notebook through an established electronic system, to facilitate reproducibility and knowledge sharing. • Stay current with advancements in bioinformatics, attending conferences, workshops, and engaging with the scientific community to remain at the forefront of the field. • Design, develop, and maintain bioinformatics pipelines, including maintaining public documentation and example workflows. • Contribute to the creation and enhancement of visualization tools, producing informative figures and visualizations for grant proposals, manuscripts, and presentations. • Conduct training sessions and create comprehensive tutorials to educate researchers on bioinformatics techniques, tools, and best practices. Qualifications EDUCATION/EXPERIENCE Required: •Master's degree in a related field •2+ years of work experience in a related job discipline OR equivalent combination of education and experience Preferred: What would we like you to have: • Proficiency in programming languages such as Python, R, or Perl. • Experience with bioinformatics tools and software for bulk RNA-seq, single cell data, ChIP-seq, ATAC-seq data analysis, etc. • Strong understanding of statistical methods and data visualization techniques. • Familiarity with genomics databases and resources. • Excellent communication skills for effective collaboration and training. • Ability to work independently and as part of a team in a dynamic research environment. Unique Skills: Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA

Description SUBFUNCTION DEFINITION: Bioinformatics applies biology, computer science, data science, and statistics to analyze and interpret biological and clinical data... REPRESENTATIVE RESPONSIBILITIES •Informatics Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in various formats (e.g., flat files, relational and non-relational databases). Collects and records appropriate metadata. Ensures data are securely stored yet highly accessible to authorized users. Develops and executes data characterization/quality assessment routines of basic to moderate complexity including metadata standardization. •Data Analysis Assists analysts and managers in building robust pipelines for curating, processing and analyzing biomedical data of various types (e.g., genomic, clinical, imaging, sequencing). Utilizes existing software and contributes to the development of new and existing tools to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage). Helps develop scalable, searchable and secure data structures, utilizing best-practices as much as possible. Incorporates institutional resources and 3rd party software into specialized analysis workflows for the team and clients. Maintains computational infrastructures and controls the flow of data and information for studies. Provides web-based bioinformatics tools and access to public and proprietary relational databases. Documents standard operating procedures based on best practice. Works in collaboration with both technology and scientific teams. •Requirements Gathering Interfaces with clinicians/researchers to collect requirements of basic to moderate complexity including user workflows. Problem-solves and discusses possible solutions with the stakeholders. Considers the implications of possible solutions on the current environment. •Software Evaluation & Development Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows. Participates in various aspects of the software development life cycle, including identification of key stakeholders, design requirements gathering, system analysis and design, code generation, testing and implementation. Effectively communicates the status of all efforts to necessary parties. Utilizes project and time management skills to complete projects within specific timeframes. •Publication Contributes to analyses and publications. Generates reports and figures for publications. Assists with materials for publications and scientific meetings. Works closely with biostaticians on the production of publication and presentation materials. Qualifications EDUCATION/EXPERIENCE Required: •Master's degree in a related field •2+ years of work experience in a related job discipline OR equivalent combination of education and experience

Description Expected Starting Salary Range: 27.60 - 35.28... SUBFUNCTION DEFINITION: Bioinformatics applies biology, computer science, data science, and statistics to analyze and interpret biological and clinical data. REPRESENTATIVE RESPONSIBILITIES • Curate genomic and biological data from scientific literature using computer readable ontologies and defined syntax including: gene expression, genes, transgenic and mutant lines, experimental, reagents, anatomy, genotype, phenotype, GO-CAMs (gene ontology) and models of human disease. • Metadata curation of transcriptomic and epigenetic high-throughput datasets. • Participate in genome annotation and gene nomenclature. • Contribute to ontology development. • Develop strategies to improve workflow, data curation, data display and website design. • Help identify and implement efficiencies. Maintain standard operating procedures. • Foster and maintain effective communications with the research community, other resources and institutions. • Co-author reports and publications and give presentations at national and international meetings and workshops. •Informatics Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in various formats (e.g., flat files, relational and non-relational databases). Collects and records appropriate metadata. Ensures data are securely stored yet highly accessible to authorized users. •Data Analysis Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g., genomic, clinical, imaging, sequencing). Utilizes existing software to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage). Utilizes web-based bioinformatics tools and public/proprietary relational databases. Follows standard operating procedures. Works in collaboration with both technology and scientific teams. •Requirements Gathering Interfaces with clinicians/researchers to collect requirements of basic to moderate complexity including user workflows. Contributes to problem-solving and solution evaluation. •Software Evaluation & Development Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows. Under general supervision, assists with implementation and testing efforts. Effectively communicates the status of all efforts to necessary parties. Utilizes project and time management skills to complete projects within specific timeframes. •Publication Contributes to analyses and publications. Generates reports and figures for publications. Assists with materials for publications and scientific meetings. Works closely with biostaticians on the production of publication and presentation materials. Qualifications EDUCATION/EXPERIENCE Required: •Bachelor of Science degree (MSc or PhD degree in biocuration and/or biomedical research preferred) • 0 - 2 years of work experience in a related job discipline Preferred: • Experience with genomics, developmental or cell biology research, particularly Xenopus. • Experience with data wrangling and programming languages such Perl, Python or R. • Experience working with ontologies, biocuration and/or biological knowledgebases. • Strong interpersonal and communication skills, including excellent written and spoken English. • Robust evidence of documentation for code and workflows. • Self-motivated with excellent time management skills. • Show ability to work in a team and independently. Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA