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More Bioinformatics Jobs

Bioinformatics Software Engineer

Boston, MA
2023/11/25.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute (DFCI) brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and... comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The Department of Informatics and Analytics (I&A) at Dana-Farber has multiple openings for highly motivated bioinformatics software or data engineers who are passionate about the potential for molecular data to inform clinical care of cancer patients and the groundbreaking discoveries that are a product of genomic data integration and analysis. The qualified candidate will work on an exciting initiative to build a cloud-based bioinformatics analysis platform. The platform will enable researchers at DFCI to easily manage their genomic and biomedical data in the cloud environment, select and kick off containerized NGS analysis workflows, monitor the execution status and eventually visualize the results. The successful candidate is expected to collaborate with functional teams such as Bioinformatics and Data Engineering, and cloud and other technology vendors. • Integrate a wide variety of tested computational tools and pipelines into cloud environment • Actively participate in designing scalable, highly available, secure, cost-effective cloud-based solutions • Collaborate with bioinformaticians and engineers to containerize new or existing analysis pipelines and make pipelines portable on both on-prem high-performance computing and cloud environments • Design, implement, and maintain scalable pipeline workflows to automate multi-step computing tasks required for various data analysis scenarios • Develop and maintain the automated tests and monitoring process to ensure the successful pipeline execution and deployment • Assist product management for the documentation of the system requirements, design, and troubleshooting • Provide technical support to end users for pipeline deployment and execution • Apply industry best practices and act as an advocate for coding standards and test-driven development • Mentor new team members Qualifications: • Bachelor’s degree required, MS preferred, in Bioinformatics, Computational Biology, Data Science, Computer Science, Software Engineering, or related discipline • Demonstrated proficiency with Python, R, Perl and/or other languages • Experience with data analysis in cloud environment, especially Microsoft Azure • Proficient with Linux environment, shell scripting, and command line tools • Experience with software development and Agile process is a strong plus SKA’s: • Enthusiastic about data security, process automation, and innovation • Familiar with distributed code versioning tools such as Git, GitHub, Bitbucket • Detail oriented with ability to gain deep understanding of technical systems • Excellent interpersonal skills, passionate about innovative solutions • Familiarity with bioinformatics workflow management such as Cromwell and Nextflow Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law. EEOC Poster

Bioinformatics Intern

Baltimore, MD
2023/11/18.

Company Overview: Labcorp is a global leader of innovative and comprehensive laboratory services that helps doctors, hospitals, pharmaceutical companies, researchers and patients make clear and confident decisions. We provide insights and advance science to improve health and improve lives through our unparalleled diagnostics and drug development laboratory capabilities. The company’s more than... 60,000 employees serve clients in over 100 countries, worked on over 80% of the new drugs approved by the FDA in 2022 and performed more than 600 million tests for patients around the world Global Internship Program: Exciting opportunity to be part of the Labcorp 2024 Global Internship Program as a Bioinformatics Intern! As a Labcorp intern, you will have the opportunity to support meaningful assignments that compliment an education in STEM+ Business and Healthcare disciplines, and are inspiring and valuable in our mission to improve health and improve lives across the globe. In addition to department work, we support your professional development and career exploration through program workshops, leadership speakers, employee resource group introductions, new hire panel discussions and small group ‘coffee chats’. Capitalize on a dedicated training and development program that will support your scientific and professional career aspirations, and take pride in delivering work that helps save the lives of millions of people around the world. About the Team: • Personal Genome Diagnostics (PGDx), a part of LabCorp, is Empowering the Fight Against Cancer by unlocking actionable information from the genome. We are developing an innovative portfolio of tissue-based and non-invasive liquid biopsy genomic products for laboratories worldwide. • The Bioinformatics and Data Science team is a multidisciplinary team of engineers and scientists providing bioinformatics and data science support for the Oncology portfolio. Internship Assignment Summary: • Support evaluation of bioinformatics pipelines and software • Contribute to technical documentation • Learn development processes in an agile • Familiarize yourself with genomics results for precision oncology products Education/Qualifications/Skills: • Working towards bachelor’s degree in Life Sciences, Bioinformatics, Computer Science or a related field • Proficiency working with data and/or software, experience working with next-generation sequencing data and/or tooling preferred • Has experience delivering multiple projects in an academic or professional setting • Ability to collaborate with various stakeholders Labcorp is proud to be an Equal Opportunity Employer: As an EOE/AA employer, Labcorp strives for diversity and inclusion in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications of the individual and do not discriminate based upon race, religion, color, national origin, gender (including pregnancy or other medical conditions/needs), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. We encourage all to apply. For more information about how we collect and store your personal data, please see our Privacy Statement

Associate Bioinformatics Data Scientist

Houston, TX
2023/11/18.

SUMMARY The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2022-2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer... Institute. The Genetics Department is a basic science department located in the George and Cynthia Mitchell Basic Sciences Research Building at the world-renowned University of Texas MD Anderson Cancer Center in the heart of the Texas Medical Center. The focus is on advancing knowledge of the molecular genetic mechanisms that regulate normal and abnormal cellular processes. The primary purpose of the Associate Data Scientist position is to provide bioinformatics analysis of next generation sequencing (NGS) data for faculty across the institution, to process NGS data for Advanced Technology Genomics Core facility, to perform quality control (QC) analysis and to maintain QC metrics and sample records of NGS experiments on the servers, and to meet with faculty to review data analysis results. This position impacts cancer research projects by developing/maintaining programs and applications tailored to meet research objectives and makes them available to the wider cancer research community. The ideal candidate will have working experience in: • Analyzing genomic and epigenomic data. • Proficiency in at least one programming language such as R, Python, or PERL. • Experience in NGS data analysis (expression profiling, mutations and structural variations, and differential peak analysis), data integration, and data mining. KEY FUNCTIONS • Performs bioinformatics analysis of bulk RNA-Seq and scRNA-Seq datasets in terms of gene expression profiling analysis. • Performs bioinformatics analysis of DNA-Seq and scDNA-Seq in terms of detection of both mutations and structural variations. • Performs bioinformatics analysis of ChIP-Seq, ATAC-Seq, and scATAC-Seq datasets in terms of genome wide profiling of histone modifications and chromosome accessibility. • Develop software pipelines to perform standard NGS data analysis routine in an automated fashion. • Perform quality control (QC) analysis on NGS data, and maintain QC metrics and sample records of NGS experiments on the servers. • Work with bioinformatics faculty, IT personnel, and other researchers to respond to new technologies. Other Skills • Expertise in programming languages such as Python, PERL, or R. • Expertise in linux/unix based environments. • Excellent communication skills and team-working attitude will be essential. • Other duties as assigned. EDUCATION Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. EXPERIENCE Required: Two years of experience in scientific software development/analysis. Preferred: • Analyzing genomic and epigenomic data. • Proficiency in at least one programming language such as R, Python, or PERL. • Experience in NGS data analysis (expression profiling, mutations and structural variations, and differential peak analysis), data integration, and data mining. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 163498 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 75,000 • Midpoint Salary: US Dollar (USD) 94,000 • Maximum Salary : US Dollar (USD) 113,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Onsite • Pivotal Position: Yes • Referral Bonus Available?: No • Relocation Assistance Available?: Yes • Science Jobs: Yes #LI-Onsite

Bioinformatics Technologist II- Ross Lab

Port St. Lucie, FL
2023/11/18.

Join Cleveland Clinic Weston Hospital’s team of caregivers that remain on the leading edge of technology and education all while consistently providing patient-centered healthcare. As part of Cleveland Clinic’s Florida region, Weston Hospital is recognized as one of the top hospitals in the Miami-Fort Lauderdale metro area and Florida. Here, you will work alongside passionate and dedicated... caregivers, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world. As a Bioinformatics Technologist II, you will develop and maintain software systems and pipelines for data processing and analysis of next generation sequencing data. You will work in a highly collaborative environment as part of a team of software engineers, computational biologists, and clinical and basic research scientists. The ideal caregiver is someone who: - Has experience with manipulation and analysis of high volume biological data. - Has experience with commonly used software tools for biological sequence analysis. - Has basic understanding of molecular biological concepts. - Has written and verbal communication skills. - Has teamwork and motivational skills. - Has organizational and multitasking skills. At Cleveland Clinic, we know what matters most. That's why we treat our caregivers as if they are our own family, and we are always creating ways to be there for you. Here, you'll find that we offer: resources to learn and grow, a fulfilling career for everyone, and comprehensive benefits that invest in your health, your physical and mental well-being and your future. When you join Cleveland Clinic, you'll be part of a supportive caregiver family that will be united in shared values and purpose to fulfill our promise of being the best place to receive care and the best place to work in healthcare. Job Description Responsibilities: • Support existing production pipelines, fix and resolve issues, as needed. • Identify, evaluate, and apply new computational methodologies and emerging technologies to improve existing methods and tools. • Analyze genomics data in partnership with experimental and computational team members, industry partners and collaborators. • Assist other lab members (graduate students, postdoctoral fellows) with training on bioinformatic tools. • Other duties as assigned. Education: • Bachelor’s degree in computer science/software engineering/bioinformatics or related field + 3 years of related experience. • Masters degree in a similar field may offset up to two years of work experience. Languages: • Language required • Language preferred Certifications: • None required Complexity of Work: • Requires critical thinking skills, decisive judgment, and the ability to work with minimal supervision. • Must be able to work in a stressful environment and take appropriate action. Work Experience: • Must possess a minimum of 3 years of relevant experience . Advanced degrees in related fields may offset 2 years of work requirement. • Experience in DNA and RNA-seq data analysis. Experience with single-cell RNA sequencing data is a plus. • Solid understanding of all stages of software development cycle. Familiarity with agile software development approach is a plus. • Fluency in programming languages (Java, Python, Perl, R), UNIX shell scripts and database management systems (MySQL or PostgreSQL). • Experience with common bioinformatics tools (BWA, Bowtie, SAMtools, GATK, MuTect, VarScan, Strelka, STAR). • Proficiency with Linux/UNIX tools in high-performance computing clusters (HPC) environment. Experience with Cloud Computing is a plus. • Excellent presentation and communication skills. Physical Requirements: • Ability to perform work in a stationary position for extended periods. • Ability to travel throughout the hospital system. • Ability to operate a computer and other office equipment. • Ability to communicate and exchange accurate information. Personal Protective Equipment: • Follows standard precautions using personal protective equipment. Pay Range Minimum hourly: $30.41 Maximum hourly: $46.38 The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement

Bioinformatics Engineer

Frederick, MD
2023/11/18.

Description Are you looking for a career that will make an impact ... The Military & Veteran’s Health Operation of Leidos is currently looking for a Bioinformatics Engineer to support biological research at the Biological Defense Research Directorate (BDRD) at the Naval Medical Research Center (NMRC) in Frederick, MD. The BDRD within NMRC facilitates biological research for the rapid detection of infectious diseases of global importance and the enhancement of global disease surveillance for early pathogen detection and response. Are you ready for unique and exciting work? The Bioinformatics Engineer plays an important role in the quality control, assembly, annotation, and dissemination of microbial (bacterial and viral) genomes in a military medical research setting. While the primary task for the Bioinformatics Engineer is to assist in microbial genome assemblies and downstream analyses to a complete (polished genome) standard, they will also contribute to other tasks such as analysis of RNAseq data and bioinformatic pipeline development and testing. Primary Responsibilities The ideal candidate shall: • Manipulate and process raw sequencing data from in-house Next Generation Sequencing (NGS) platforms (MiSeq, NextSeq500, Ion S5, PacBio, MinION), microarrays, publicly accessible databases, and/or external collaborators. • Perform quality control, assembly, annotation, etc. • Integrate high-throughput data from multiple sequencing platforms. • Use a variety of bioinformatic tools and potentially develop new software applications to solve salient problems in the field of genomics. • Download, install, and benchmark open-source software packages from a variety of sources (GitHub, SourceForge, etc.). • Assist staff scientists in summarizing research data, preparing posters, and/or presenting results via conference presentations, scientific publications, or project reports. • Attend internal meetings and teleconferences as well as external meetings with collaborators and stakeholders when deemed appropriate. • Contribute to technical reports, presentations and manuscripts for publication. • Assist with appropriate training of other personnel. • Work is to be performed on a government installation. The normal work week is Monday - Friday 0800 to 1630. • Candidates may need to work evenings and weekends on very rare occasions. If this sounds like an environment where you can thrive, keep reading for the keys to success! Required Education, Knowledge, Skills and Abilities: • Candidates must have completed a Bachelor’s or Master’s degree from an accredited US university, or international university of equivalent standard, in Bioinformatics, Computer Science (combined with experience or education in biology or bioinformatics), Computational Biology, Mathematics or a closely related area. • Candidates must have at least 2-4 years of hands-on experience in Bioinformatics. • Possess programming skills in languages such as JAVA, PERL, PYTHON, and statistical software such as R or R Studio. • Maintain a familiarity with next generation sequencing and microarrays. • Have excellent verbal and writing communications skills. • Be able to think independently and must have excellent problem-solving skills. • The candidate will be required to acquire, at a minimum, a SECRET classification access level. Preference will be given to a candidate who already has this clearance level. • Due to Federal contract requirements, US citizenship is required. • Strong background in genomics, bioinformatics computer science, bacterial or viral genetics, and/or computational biology. • Be able to perform under deadlines and in austere environments. Preferred Qualifications • Experience in a military medical research laboratory is a plus. • Ability to work well independently with little to no supervision. Naval Health East - NHE Pay Range: Pay Range $63,050.00 - $113,975.00 The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law. #Featuredjob

Senior Bioinformatics Analyst/Bioinformatics Analyst

Memphis, TN
2023/11/18.

St. Jude Children's Research Hospital is looking for a highly motivated Senior Bioinformatics Analyst/Bioinformatic Analyst to contribute to genetic research projects in the Department of Epidemiology and Cancer Control. Our research leverages comprehensive biomedical data from childhood cancer survivors participating in two world-leading cohort studies, CCSS (https://ccss.stjude.org/ ) and... SJLIFE (https://sjlife.stjude.org/ ), to identify novel genetic determinants of childhood-cancer-treatment-related outcomes using advanced data-science methods. One of our ongoing research theme is on rare variant/haplotype analysis (Wang et al. Cancer Res 2023; Letsou et al. Life Sci Alliance 2023), aiming to apply to the CCSS/SJLIFE data. As a Bioinformatics Analyst, you will work under the supervision of a Lead Bioinformatics Scientist on various genetic analyses such as GWAS, rare variant/haplotype analysis, polygenic risk score, and epistatic analysis. You will also assist in evaluating new genetic computational methods, acquiring data from public databases (e.g., UK Biobank, TOPMED, dbGaP, GEO, gnomAD, GTEx), and sharing the analytic workflow and resources with the department and the research community. The ideal candidate should demonstrate good data analytic skills and be familiar with Shell scripting languages as well as high-performance cluster computing environment (HPC). Good understanding of genetics and molecular biology is preferred, but it is not required. In this position, you will have opportunities to advance computation skills in analyzing extensive genomic data using HPC and cloud environments, gain knowledge of pediatric cancer, its treatment, and contribution of germline genetics to the late effects of cancer therapy, and have co-authorship in scientific publications of all projects you contribute to. Job Responsibilities: • Evaluate data for quality assurance and mine relevant (e.g., bioinformatics, biomedical, cheminformatics) databases. • Perform basic analysis, algorithm implementation, programming, and quality checks on data to be loaded into a biomedical database. • Assist in adopting new and improved tools and web-based applications. • Assist in evaluating products and solutions pertaining to the department’s technology needs, in maintaining databases or data warehouse and project reports. • Perform other duties as assigned to meet the goals and objectives of the department and institution. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree preferred. Senior Bioinformatics Analyst Minimum Experience: • Minimum Requirement: 4+ years of relevant experience required. • Experience Exception: Master's degree and 1+ years of relevant experience. • Experience in at least one programming or scripting language and at least one statistical package, with R preferred Bioinformatics Analyst Minimum Experience: • Minimum Requirement: 2+ years of relevant experience required. • Experience Exception: Master's degree and no experience. • Experience in at least one programming or scripting language and at least one statistical package, with R preferred. St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Bioinformatics Developer III

Pleasanton, CA
2023/11/18.

We are seeking an experienced Bioinformatics Developer to join the Life Sciences Group at Bio-Rad and help us develop a new generation of cloud-based software for assays designed specifically for our industry-leading droplet digital PCR (ddPCR) platforms. As a Bioinformatics Developer, you will be able to see your ideas mature from conception to launch while creating efficient tools and novel... algorithms for our ddPCR portfolio. The ideal candidate is someone with a strong background in designing PCR assays. Effective communication across a wide variety of audiences, including those without prior bioinformatics experience, is also highly sought after. Likewise, candidates should be capable of making evidence-based decisions and seeking out opportunities for growth. We look forward to having you join us in the Life Sciences Group so we can lead the way into the next stage of ddPCR discovery together. How You'll Make An Impact: • Provide scientific and technical expertise in bioinformatics as part of a diverse research and development team. • Design and develop scalable, reproducible, and customer-focused bioinformatics software for designing ddPCR assays. • Support the custom assay design needs of internal R&D scientists, sales team, and customers. • Communicate with a variety of stakeholders across Bio-Rad to present work and develop collaborations. • Create tools for internal research and development, such as assessing assay performance and novel assay design tool prototyping. • Utilize test-driven development to ensure software deliverables are robust and meet requirements. • Identify and address opportunities for code and/or process optimization. What You Bring: Education: • PhD or MS degree in molecular biology, bioinformatics, or computer science OR • Bachelor's degree in molecular biology, bioinformatics, or computer science with equivalent experience Work Experience: • At least 3 years of experience designing PCR assays for DNA and/or RNA detection and quantification. • Proficient in Python programming. • Experience developing software with OOP paradigm and design patterns. • Experience writing code to manipulate and analyze complex genomic measurements. • Experience using reference genomes and transcriptome models databases. • Experience with ORM and managing databases, e.g. MySQL, PostgreSQL. • Experience with cloud computing platforms (AWS, Microsoft Azure, Google Cloud). • Fluent (written and spoken) English.  The following will be desirable but not essential: · Basic understanding of cancer genomics and databases. • Experience with assay design for bacteria, viruses, and fungi. • Experience with design control processes. • Fundamental knowledge of testing frameworks (e.g., Pytest, unittest). • Experience with RESTful API. Total Rewards Package: At Bio-Rad, we’re empowered by our purpose and recognize that our employees are as well. That’s why we offer a competitive and comprehensive Total Rewards Program that provides value, quality, and inclusivity while satisfying the diverse needs of our evolving workforce. Bio-Rad's robust offerings serve to enrich the overall health, wealth, and wellbeing of our employees and their families through the various stages of an employee’s work and life cycle. Benefits: We’re proud to offer a variety of options, including competitive medical plans for you and your family, free HSA funds, a new fertility offering with stipend, group life and disability, paid parental leave, 401k plus profit sharing, an employee stock purchase program, a new upgraded and streamlined mental health platform, extensive learning and development opportunities, education benefits, student debt relief program, pet insurance, wellness challenges and support, paid time off, Employee Resource Groups (ERG’s), and more! Compensation: The estimated base salary range for this position is $127,000 to $174,700 at the time of posting. Actual compensation will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. This position is eligible for a variable annual bonus, which is dependent upon achievement of your individual objectives and Company performance. Who We Are: For 70 years, Bio-Rad has focused on advancing the discovery process and transforming the fields of science and healthcare. As one of the top five life science companies, we are a global leader in developing, manufacturing, and marketing a broad range of high-quality research and clinical diagnostic products. We help people everywhere live longer, healthier lives. Recently voted a Best Place to Work, Bio-Rad offers a unique employee experience with collaborative teams that span the globe. Here, you are supported by leadership to build your career and are empowered to drive change that makes an impact you can see. EEO Statement: Bio-Rad is an Equal Employment Opportunity/Affirmative Action employer, and we welcome candidates of all backgrounds. Veterans, people with physical or mental disabilities, and people of all race, color, sex, sexual orientation, gender identity, religion, national origin and citizenship status are encouraged to apply. Agency Non-Solicitation: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Recruiting Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes. #LI-PB1

Sr Scientist I, Bioinformatics Engineer

Illinois
2023/11/18.

The Genomics Research Center (GRC) is a center of excellence for genetics and genomics that supports both Discovery and Development. The GRC plays an integral role towards our goal of developing extraordinary genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in... clinical trials. Within the GRC, the Department of Bioinformatics is responsible for data analysis and provides analytical insight for both internal and external data. This involves the identification and characterization of underlying genetic, epigenetic, or genomic factors that are associated with disease diagnosis, prognosis, and response (efficacy and safety) to drug treatment, identification of new targets, and interpretation of the impact of genetic and genomic evidence from population-based studies. To attend to these challenges, we have an exciting opportunity for a Bioinformatics Engineer in the Pipeline Development team. The candidate will work closely with other engineers, computational biologists, and research project teams to develop and deploy processing and analysis pipelines that enable and accelerate novel drug discovery. Responsibilities: • Develop and support NGS pipelines using scientific workflow language via best practices, including unit testing, CI/CD, containerization, and code reviews. • Identify, design, and implement internal process improvements: automating manual processes, optimizing data delivery, re-designing infrastructure for greater scalability, etc. • Design, develop and maintain Application Programming Interfaces (APIs), microservices, and asynchronous queuing systems. • Create and maintain documentation for project work. • Present project contributions in a range of settings (engineering peers, stakeholder sessions, broader AbbVie science-sharing events). • Work with bioinformatic scientists as the stakeholders to assist with data-related technical issues and support their data infrastructure needs. • Communicate with research-serving IT support to resolve on-prem and cloud HPC infrastructure obstacles. Qualifications: • Bachelor’s or Master’s, or PhD in Software Engineering, Computer Science, data scientist/engineering, bioinformatics, computer and electrical engineering, or related field with typically 10+ (BS), 8+(MS), or 0+ (PhD) years of relevant experience. • Fluency in Python and familiarity with SQL and database technologies. • Experience with at least one scientific workflow language such as CWL, WDL, nextflow, or snakemake. • NGS bioinformatics pipeline development experience. • Demonstrated experience with container technology (Docker, Singularity/Aptainer) • AWS Data Platform experience: S3, EC2 • Familiarity with data workflow development and ETL process. • Familiarity with standard tools and data formats related to genomics resequencing projects processing and analysis. • Strong communication skills in a collaborative environment. AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status

Bioinformatics Programmer I - 125271

California
2023/11/18.

Payroll Title: BIOINFORMATICS PROGR 1 Department: MEDICINE/Cardiology Hiring Pay Scale... $25.67 - $33.00 / Hour Worksite: Campus Appointment Type: Career Appointment Percent: 100% Union: Uncovered Total Openings: 1 Work Schedule: Days, 8 hrs/day, Mon - Fri #125271 Bioinformatics Programmer I Initial Review Date: Wed 9/27/2023 Apply Now UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply. UCSD Layoff from Career Appointment: Apply by 09/15/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 09/27/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will remain open until a successful candidate has been identified. DESCRIPTION The Department of Medicine (DOM) is the largest department within the UCSD School of Medicine and is responsible for fulfilling the teaching, research, and clinical missions of the University of California, San Diego School of Medicine. The department employs approximately 500 salaried faculty, 168 academic appointees, 331 residents, fellow and postdocs and 479 staff personnel. Computational biologist. Resolves routine programming problems, applying established data processing algorithms to novel data. Works on issues and projects of limited scope. Follows standard programming procedures to analyze situations and data from which answers can be readily obtained. Maintains repositories of published code and answers outside user requests. Aids in the publications of research results. Proficiency in Python, R, Linux, and git version control systems required. AWS experience is a plus. Understanding of major biological data types (genomic SNPs, single-cell RNA-seq expression, protein-protein interaction networks, ATAC-seq, Chip-seq) is required. Will design and develop bioinformatic programs and pipelines to process genomics data. Responsible for lab computer and software maintenance and coordination with other computer facilities. Under direct supervision, applies professional bioinformatics concepts and computational procedures to complete small projects or portions of projects. Works on assignments of limited scope and complexity. Follows standard programming procedures to analyze situations and data from which answers can be readily obtained. MINIMUM QUALIFICATIONS • Four (4) years of related experience, education/training, OR a Bachelor's degree in bioinformatics, biological science, computational / programming, or related area and /or equivalent experience/training. • Basic knowledge of bioinformatics methods, techniques, and data structures. • Programming experience: R, Python, Linux, bash scripting, git version control systems. • Demonstrated experience in processing and analyzing genomics data. • Proven knowledge of applications programming and web development. • Knowledge of modern biology and applicable field of research. Theoretical knowledge in molecular, cellular, or developmental biology. • Effective interpersonal skills in order to work with both technical and non-technical personnel at various levels in the organization. • Strong ability to communicate technical information in a clear and concise manner. • Basic knowledge of application and data security concepts. PREFERRED QUALIFICATIONS • Knowledge of AWS, Jupyter Notebook, HPC • Knowledge relating to the design development, modification and implementation of software including object-oriented programming concepts. • Understanding of major biological data types (genomic SNPs, RNA-seq expression, protein-protein interaction networks. • Experience analyzing singlecell and spatial transcriptomics data. SPECIAL CONDITIONS • Employment is subject to a criminal background check. Pay Transparency Act Annual Full Pay Range: $53,600 - $111,600 (will be prorated if the appointment percentage is less than 100%) Hourly Equivalent: $25.67 - $53.45 Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable). Apply Now If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements. If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable. UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team! Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached. To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community. UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information. UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening

Lead Bioinformatics Research Scientist/ Senior Bioinformatics...

Memphis, TN
2023/11/18.

The Lead/Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development with a focus on the Genomics data. Provides bioinformatics analysis for investigators and communicates analytical process and results. The Genomics Group from the Center for Applied... Bioinformatics at St. Jude Children's Research Hospital is looking for a highly motivated and creative Senior Bioinformatics Research Scientist or Bioinformatic Research Scientist to develop and apply innovative analytical approaches to understand the underlying mechanisms that drive pediatric cancers and other human diseases. Working for all different projects together with different PIs, employee could make a valuable difference not only to science but also to pediatric cancer patient curation and survival. Besides the various analysis tasks, we also encourage exploring newly available methods, pipeline development could result in first author, high profile publications, as long as it aligns with our ultimate goal: “Finding cures. Saving children”. The Center provides a highly interactive environment with collaborative opportunities within the centers including transcriptomics group, genomics group, and genetics group, and across basic and clinical departments, access to high-performance computing clusters, cloud computing environment, novel sequencing platforms such as long reads sequencing technologies, single-cell sequencing at both DNA and RNA level and spatial transcriptomics, innovative visualization tools, highly automated analytical pipelines powered by GPU technology and mentorship from scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The members of this Center could work on broad areas of bioinformatics and gain valuable experiences. The members of this Center also have the opportunity to publish high-profile papers with prominent authorship and file patents for novel biomarker discoveries or novel methods for clinical diagnosis or disease treatment. Good candidates will have experience in building and optimizing analysis workflows using publicly available software/pipelines for high-throughput next-generation sequence data analysis (such as whole-genome sequencing, whole-exome, targeted sequencing and so on) under Linux/Unix environment. The successful candidate is expected to have good programming skills in Bash, Python, and R. Experience with cancer genomics is a plus. St. Jude has been frequently made up to Great Place to Work list such as in Fortune magazine’s “Best Workplaces in Health Care & Biopharma™ 2020” list and GlassDoor's "BEST PLACES TO WORK 2023" list. Salary is highly competitive (comparable to industry) and employee benefits are outstanding. This position is located at Memphis, TN, and relocation assistance is available. Responsibilities • Specific responsibilities may involve NGS data quality control, integrative analyses, data visualization, developing and evaluating analytic tools • Excellent communication skills are essential • You will work closely with St. Jude PIs to provide standardized/customized analysis, using St. Jude high-performance computing clusters or a cloud computing environment Minimum Requirements • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Lead Bioinformatic Research Scientist • Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Senior Bioinformatics Research Scientist • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred Bioinformatics Research Scientist • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with Python preferred Other Information St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

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