Bioinformatics Jobs

The Department of Medicine, Division of Cardiovascular Medicine at Stanford University is seeking a talented Bioinformatics Engineer to join the Bioinformatics Core (BIC) of the Molecular Transducers of Physical Activity Consortium (MoTrPAC). As part of this groundbreaking national research consortium, you will help unravel the molecular mechanisms underlying the benefits of physical activity. Under the supervision of co-PIs Dr. Euan Ashley and Dr. Matthew Wheeler, you will play a crucial role in shaping the future of personalized exercise science and public health. Dr. Euan Ashley's research interests focus on the application of genomics and other omics data to improve clinical care, with an emphasis on cardiovascular disease and personalized medicine. Dr. Matthew Wheeler's research centers on the integration of large-scale molecular and clinical data to understand the genetic basis of cardiovascular diseases and to develop novel therapeutic strategies. By joining our team, your proficiency in applying advanced statistical methodologies, such as multivariate analysis, machine learning, and Bayesian approaches, will be essential for uncovering novel insights and driving innovation in our research efforts. Your strong statistical background and expertise in analyzing large biological datasets. experience in handling diverse omics data will contribute significantly to our understanding of complex biological systems and the development of personalized medicine. You will also contribute to the analysis, execution, and development of pipelines and bioinformatic tools for various omics data generated within MoTrPAC. This innovative project integrates large volumes of clinical and densely time-sampled molecular data, pushing the boundaries of biomedical data analytics. Our portal (https://motrpac-data.org) will push the boundaries of biomedical data analytics to provide insight into the basic and translational science of exercise. Working alongside our multidisciplinary team, you will be at the forefront of understanding how physical activity preserves and improves health, ultimately making a lasting impact on human well-being. To find out more about our studies, you can check our recent publication in Nature and other journals about the endurance exercise training in rats (visit https://motrpac-data.org/publications). To be considered, please submit a resume and a cover letter that describes your interest in this position, and what skills you would bring to this role. Responsibilities: As a Bioinformatics Engineer II, you will contribute to the analysis, execution, and development of pipelines and bioinformatic tools for various omics data generated within the MoTrPAC project. Your primary responsibilities will include: • Collaborate with a multidisciplinary team of scientists and engineers to analyze and interpret large-scale multi-omics data. • Develop and implement innovative bioinformatics tools and methods to further our understanding of molecular mechanisms underlying the effects of physical activity. • Prepare reports and presentations to communicate findings with the team and the larger scientific community. Qualifications: To be successful in this role, you should possess an advanced degree (Ph.D. or M.S.) in a field such as statistics, biomedical informatics, engineering, or computer science along with a minimum of two years of relevant professional experience. They should have expertise in the analysis, execution, and development of pipelines and bioinformatic tools for various omics data and be proficient in programming languages like R and/or Python, as well as Linux bash scripting. Familiarity with pipeline languages, container systems, code management platforms, and systems biology approaches for data integration is also essential. Candidates should demonstrate experience in large-scale data analysis (with emphasis on genomics, transcriptomics, epigenomics datasets), biological domain knowledge, bioinformatics, and software development team-based projects. Additionally, they should be willing to work in a highly collaborative environment, be able to adapt quickly, possess strong communication skills, and have the capacity to work independently. Due to extensive teamwork needed, this is a mostly on-site position. Why Join Us? • Work on a highly exciting and innovative multi-omics project with the potential to revolutionize our understanding of physical activity and health. • Be part of a world-class research team at Stanford University, led by Dr. Euan Ashley, a pioneer in personalized medicine. • Contribute to groundbreaking research with a significant impact on public health and the prevention of diseases. • Enjoy a collaborative and stimulating work environment at one of the top universities in the world. If you are a passionate and dedicated professional with the required qualifications and a strong interest in advancing scientific research, we encourage you to apply for this exciting opportunity. Join us in unraveling the mysteries of physical activity and making a lasting impact on human health. A complete application will include a cover letter. Duties include: • Prioritize and extract data from a variety of sources such as notes, survey results, medical reports, and laboratory data, and maintain its accuracy and completeness. • Determine additional data collection and reporting requirements. • Design and customize reports based upon data in the database. Oversee and monitor regulatory compliance for utilization of the data. • Use system reports and analyses to identify potentially problematic data, make corrections, and eliminate root cause for data problems or justify solutions to be implemented by others. • Create complex charts and databases, perform statistical analyses, and develop graphs and tables for publication and presentation. • Serve as a resource for non-routine inquiries such as requests for statistics or surveys. • Test prototype software and participate in approval and release process for new software. • Provide documentation based on audit and reporting criteria to investigators and research staff. DESIRED QUALIFICATIONS: • Graduate degree (MS, PhD) emphasizing statistics, biomedical informatics, engineering, and computer science are preferred. • Domain expertise in analysis and running pipelines and bioinformatic tools for at least one of the following ‘omes: genomics, transcriptomics, epigenomics (ATAC-seq, RRBS). Knowledge of metabolomics and proteomics analysis is a plus. • Experience in systems biology approaches for data integration. • Proficiency in Python and/or R and Linux bash scripting. • Experience and knowledge of code management such as GitHub. • Experience with pipeline languages such as WDL, snakemake, and/or nextflow. • Proven track record of working with data and infrastructure in an HPC (High-Performance Computing) cluster or cloud computing environments like Google Cloud Platform, AWS, or Azure. • Experience with container systems such as setting up virtual machines and docker instances. • Experience in developing tools and statistical methods for large-scale data analysis is a plus. • Biological domain knowledge (exercise science is a plus). EDUCATION & EXPERIENCE (REQUIRED): • Bachelor's degree and three years of relevant experience or combination of education and relevant experience. • Experience in a quantitative discipline such as economics, finance, statistics or engineering. KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED): • Substantial experience with MS Office and analytical programs. • Excellent writing and analytical skills. • Ability to prioritize workload. CERTIFICATIONS & LICENSES: • None PHYSICAL REQUIREMENTS*: • Sitting in place at computer for long periods of time with extensive keyboarding/dexterity. • Occasionally use a telephone. • Rarely writing by hand. WORKING CONDITIONS: • Some work may be performed in a laboratory or field setting. WORKING STANDARDS: • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations. • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned. • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu/. The expected pay range for this position is $104,358 to $128,038 per annum. Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs. At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process. Why Stanford is for You Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with: • Freedom to grow. We offer career development programs, tuition reimbursement, or audit a course. Join a TedTalk, film screening, or listen to a renowned author or global leader speak. • A caring culture. We provide superb retirement plans, generous time-off, and family care resources. • A healthier you. Climb our rock wall or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits. • Discovery and fun. Stroll through historic sculptures, trails, and museums. • Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more. Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources by submitting a contact form. Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

The Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Provides bioinformatics analysis for investigators and communicates analytical process and results. The recently established Microbial Computational Genomics and Bioinformatics Laboratory in the new Department of Host-Microbe Interactions (HMI) at St Jude Children’s Research Hospital is looking for a Senior Bioinformatics Research Scientist to work on the analysis of microbial and host omics datasets, with a significant focus on comparative analysis of bacterial and viral genomic datasets. The Microbial Computational Genomics and Bioinformatics Laboratory provides HMI and Center for Infectious Diseases Research (CIDR) faculty with top-notch computational biology core support for omics projects and analyses, especially genomics and transcriptomics. Our team collaborates with and provides support to researchers within the HMI and other departments, including Infectious Diseases, through CIDR to provide study design and analysis support at different stages of their research, from study conception and design, data analysis and interpretation for dissemination via talks and manuscripts, and contributing to grant proposals and manuscripts as authors or co-authors. We aim to become a leading team conducting cutting-edge microbial omics and bioinformatics research and supporting researchers within HMI, CIDR, and beyond. The laboratory is a significant initiative backed by substantial support as a part of our institutional strategic plan. The team is fully integrated in research in microbial evolution, microbial pathogenesis, virology, the microbiome, computational biology, and data sciences at St. Jude Children’s Research Hospital. The successful candidate will join a team of Bioinformaticians and will work with other groups at St. Jude, including clinicians, basic scientists, and data scientists, to establish pipelines, analytical approaches, and best practices to facilitate data processing and analysis of microbial and host omics datasets. As a Senior Bioinformatics Research Scientist, you will perform data analysis, develop bioinformatics pipelines and analytical solutions, and play an integral role in research partnerships to explore the application of bioinformatics to omics datasets to support the needs of researchers in the HMI department, the CIDR, within the wider St Jude community, and with external collaborators beyond St Jude. The candidate will be required to follow and adhere to best practices in project management through efficient planning of projects and formulating specific milestones of research goals, monitoring of progress, anticipating and identifying barriers to success and proposing solutions, and providing informative feedback, progress reports, and summaries to the Director of the Microbial Computational Genomics and Bioinformatics Laboratory and principal investigators within HMI and CIDR. The position will report to the Director of the Microbial Computational Genomics and Bioinformatics Laboratory. The Microbial Computational Genomics and Bioinformatics Laboratory will provide a highly collaborative and interactive environment with researchers within HMI, CIDR, and beyond. The successful candidate will have access to the state-of-the-art St Jude high-performance computing (HPC) infrastructure, cloud computing, and innovative tools and datasets. There will be opportunities to advance scientifically through authorships of high-profile papers depending on their specific intellectual contributions. This is an excellent position to join a newly established laboratory core team to conduct cutting-edge microbial omics and bioinformatics research and support researchers within HMI, CIDR, and St Jude to contribute to the mission of St. Jude Children’s Research Hospital to advance cures and means of prevention, for pediatric catastrophic diseases through research and treatment. The ideal candidate should have: – A PhD and extensive experience in microbial bioinformatics, computational biology, and data science, with practical experience working with microbial omics datasets and familiarity with the basic biology of microbial pathogens, especially bacteria and viruses. – A CV with a strong publication record in bioinformatics, computational biology, and data science, mainly focusing on microbial pathogens. – Experience and keen interest in analyzing diverse and large-scale datasets, including whole genome sequencing, phylogenomics, transcriptomics (bulk and single-cell), metagenomics (16S rRNA and shotgun sequencing), transposon sequencing (Tn-seq), and metatranscriptomics using short and long-read sequencing data. – Knowledge of other bioinformatics skills such as genome annotation, DNA methylation analysis, protein structure modeling, metabolomics, and proteomic data analysis will be an added advantage. – Proficient in statistical analysis and working with statistical software (e.g., R), data visualization (e.g., using ggplot2, Matplotlib/Seaborn, and R Shiny), programming languages (e.g., Python), and database software (SQL or NoSQL) preferably in a Linux environment. – Experience using High-Performance Computing (HPC) workload management software, including SLURM and LSF. – Knowledge of software tool development and version control software, such as GitHub, GitLab, Bitbucket, Mercurial, and Mercurial. – A keen interest in generating reproducible code and software using workflow management systems such as Nextflow and Snakemake. – Resilient, problem-solver, critical thinker, and able to work collaboratively in a team environment under direction and with minimal supervision. – Excellent communication and presentation skills in biological research and bioinformatic methodology. – Demonstrated ability to be a fast learner, motivated to continuously advance professionally and stay up-to-date with recent advances in the bioinformatics field, flexible and adaptable to change, move between projects easily, and provide support/expertise where needed. – Previous experience working in the field of infectious diseases is preferred. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist – Microbial Genomics. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The Opportunity The Faculty Cluster Initiative (FCI) at the University of Central Florida (UCF) is recruiting for a 9-month tenured professor who will act as the lead for the Genomics and Bioinformatics Cluster (https://www.ucf.edu/research/genomics-bioinformatics/). This position has an anticipated start date of August 8, 2025. An ideal candidate should have a strong background in genomics and bioinformatics, and in computational approaches used to analyze large genomic datasets. The candidate should have demonstrable leadership experience, preferably with multidisciplinary teams, and a strong record of continual extramural funding. The new Genomics and Bioinformatics Cluster lead can join any of three host departments - The Burnett School of Biomedical Sciences (College of Medicine), Biology (College of Sciences), or Computer Science (College of Engineering and Computer Science); or be jointly appointed among them as appropriate to qualifications and interest. The cluster lead will be expected to develop a research program that strengthens their tenure home department and the cluster. UCF is one of the nation's largest universities with a diverse student body of approximately 68,000 students. UCF has grown substantially in size, quality, diversity, and reputation in its first 50 years. Today, the university offers 240 degree programs. UCF is an economic engine, attracting and supporting industries vital to the region's future while providing students with real-world experiences that help them succeed after graduation. Minimum Qualifications: A Ph.D. or equivalent Doctoral degree from an accredited institution in computer science, bioinformatics, computational biology, biological sciences, biomedical sciences, or a closely related discipline. Extensive experience in cutting-edge bioinformatics methods, with applications in biological sciences, biomedical sciences, or AI in medicine. A strong, consistent, and recent funding record from the NIH, NSF, or other equivalent agencies in genomics and bioinformatics and demonstrated leadership in interdisciplinary research and/or education programs, potentially evidenced by currently, or previously, having held a leadership position at one's current, or a previous, academic institution. To be eligible for appointment as a tenured professor upon hire, the selected candidate must have a demonstrated record of teaching, research, service, and leadership commensurate with a tenured faculty appointment at the rank of professor, in the applicable tenure home. Evidence of such a record could be demonstrated by holding the rank of full professor at one's current institution. Preferred Qualifications: The ideal candidate would also have proficient teaching skills and the capacity to communicate effectively with both graduate and undergraduate students, whether in large or small audiences. Additional Application Materials Required: UCF requires all applications and supporting documents to be submitted electronically through the Human Resources employment opportunities website, https://www.ucf.edu/jobs/. In addition to the online application, candidates should upload a cover letter, a current curriculum vitae, a statement of career goals no more than 3 pages discussing their research, teaching, and their vision to lead an interdisciplinary bioinformatics and genomics group, and a list with contact information for three (3) professional references. In the cover letter, candidates should address their background in genomics and bioinformatics, their leadership experiences, and should identify the anticipated department(s) for their potential tenure home. NOTE: Please have all documents ready when applying so they can be simultaneously uploaded. Once the online submission process is finalized, the system does not allow applicants to submit additional documents later. Questions regarding this search should be directed to Naya Ramirez, HR Partner, Search Committee Manager, at Nayade.Ramirez@ucf.edu; or to Maria Fernandez, Human Resources Coordinator III, Search Committee Manager, at Maria.Fernandez@ucf.edu. Review of applications will begin in October 2024 and continue until the position is filled. Special Instructions to the Applicants: N/A Job Close Date: Open until filled. Note to applicants: Please keep in mind that a job posted as 'Open until filled' may close at any time without notice. As such, we encourage you to submit your application and all required documentation as quickly as possible to ensure consideration for the posted position. Are you ready to unleash YOUR potential? As a next-generation public research university and Forbes-ranked top employer in Florida, we are a community of thinkers, doers, creators, innovators, healers, and leaders striving to create broader prosperity and help shape a better future. No matter what your role is, when you join Knight Nation, you'll play an integral role at one of the most impactful universities in the country. You'll be met with opportunities to connect and collaborate with talented faculty, staff, and students across 13 colleges and multiple campuses, engaging in impactful work that makes a positive difference. Your time at UCF will provide you with many meaningful opportunities to grow, you'll work alongside talented colleagues on complex projects that will challenge you and help you gain new skills and you'll have countless rewarding experiences that go well beyond a paycheck. Working at UCF has its perks! UCF offers: • Benefit packages, including Medical, Dental, Vision, Life Insurance, Flexible Spending, and Employee Assistance Program. • Paid time off, including annual (12-month faculty) and sick time off and paid holidays. • Retirement savings options. • Employee discounts, including tickets to many Orlando attractions. • Education assistance. • Flexible work environment. • And more...For more benefits information, view the UCF Employee Benefits Guide click here. Unless explicitly stated on the job posting, it is UCF's expectation that an employee of UCF will reside in Florida as of the date the employment begins. Additional Requirements related to Research Positions: Pursuant to Florida State Statute 1010.35, prior to offering employment to certain individuals in research-related positions, UCF is required to conduct additional screening. Applicants subject to additional screening include any citizen of a foreign country who is not a permanent resident of the U.S., or who is a citizen or permanent resident but is affiliated with or has had at least 1 year of education, employment, or training in China, Cuba, Iran, Russia, North Korea, Syria, or Venezuela. The additional screening requirements only apply to research-related positions, including, but not limited to faculty, graduate positions, individuals compensated by research grants or contract funds, post-doctoral positions, undergraduate positions, visiting assistant professors, and visiting research associates. Department Office Of Research, Research Centers & Institutes, College Of Graduate Studies, And Burnett Honors College HR Business Center Work Schedule Varies Type of Appointment Regular Expected Salary Negotiable Equal Employment Opportunity Statement: The University of Central Florida is an Equal Opportunity/Affirmative Action Employer including Disabled/Vets. Click on UCF's Equal Opportunity Statement to view the President's Statement. The UCF affirmative action plans for qualified individuals with disabilities and protected Veterans are available for inspection in the Office of Institutional Equity, Monday through Friday, from 9:00 a.m. to 5:00 p.m., upon request. As a Florida public university, UCF makes all application materials and selection procedures available to the public upon request. The University of Central Florida is proud to be a smoke-free campus and an E-Verify employer.

The US Air Force School of Aerospace Medicine (USAFSAM) has a bioinformatics fellowship opportunity open to those who have obtained a master's degree in the field of Biological Sciences, Public Health, Biocomputing, or similar field. What will I be doing? As an Oak Ridge Institute for Science and Education (ORISE) participant, you will join a community of scientists and researchers in an effort to further the fellow’s knowledge of infectious disease surveillance, wastewater surveillance, genomic sequencing, and data collection, management and visualization. The purpose of this training fellowship is to provide an educational experience to individuals interested in the fields of public health, infectious disease, epidemiology, and surveillance. The fellow will gain insight into how to communicate data and findings from a surveillance network to decision-makers, other researchers, and the public. Fellows will train within the United States Air Force School of Aerospace Medicine’s Applied Technology and Genomics division and can expect to gain valuable experiences in bioinformatics, high performance computing, and infectious disease surveillance. The fellow will also participate in activities related to database cleaning, data analysis, data visualization, and interpretation of results. The fellow may also have opportunities to develop manuscripts and/or posters or oral presentations for academic conferences. Why should I apply? Under the guidance of a mentor, you will gain hands-on experience to support your academic and professional goals. Along the way, you will engage in activities and research in several areas. These include, but are not limited to: • Analyze large-scale data and summarize findings using statistical software • Develop analysis pipelines and workflows utilizing available platforms • Perform data analysis and develop visualizations using public and in-house tools and dashboards • Collaboration and participation in meetings • Be involved with verbal and written presentations of studies at scientific conferences • Preparation of literature searches, scientific manuscripts, posters, presentations, and other information Where will I be located? The location of this appointment may vary. What is the anticipated start date? Exact start dates will be determined at the time of selection and in coordination with the selected candidate. Applications are reviewed on an ongoing basis and internships will be filled as qualified candidates are identified. What is the appointment length? This appointment is a twelve-month research appointment at a full-time level of participation. Appointments may be extended depending on funding availability, project assignment, program rules, and availability of the participant. What are the appointment provisions? You will receive a stipend to be determined by USAFSAM. Stipends are typically based on a participant’s academic standing, discipline, experience, and research facility location. Other provisions may include the following: • Health Insurance Supplement (Participants are eligible to purchase health insurance through ORISE) • Relocation Allowance • Training and Travel Allowance About USAFSAM The 711th Human Performance Wing’s U.S. Air Force School of Aerospace Medicine (USAFSAM) was established in 1918 and is the premier institute for education and worldwide operational consultation in Aerospace and Operational Medicine. USAFSAM has been a leader in the field of aerospace medicine and human performance from the beginnings of aviation through the onset of the space age and into the present, and is the oldest continually operating institution of its kind. It is also host to the largest aeromedical library in the world. By joining forces with the Air Force and Navy Research Laboratories, USAFSAM fully leverages aeromedical, science, and technology to optimize performance, health, and survival of healthy humans in abnormal or extreme environments, including combat, air, space, and cyberspace. The Applied Technology and Genomics (PHT) Division is a Biosafety Level-2 laboratory, and the only research genetics laboratory in the USAF that can support several projects focusing on: bacterial/viral culture, DNA/RNA extraction, PCR amplification, DNA printing (primers/probes/synthetic constructs), next-generation sequencing, microscopy, analysis of genetic code, and secured storage of genetic code. About ORISE This program, administered by Oak Ridge Associated Universities (ORAU) through its contract with the U.S. Department of Energy (DOE) to manage the Oak Ridge Institute for Science and Education (ORISE), was established through an interagency agreement between DOE and DoD. Participants do not enter into an employee/employer relationship with ORISE, ORAU, DoD or any other office or agency. Instead, you will be affiliated with ORISE for the administration of the appointment through the ORISE appointment letter and Terms of Appointment. Proof of health insurance is required for participation in this program. Health insurance can be obtained through ORISE. For more information, visit the ORISE Research Participation Program at the U.S. Department of Defense.

Description: As an active team member of the Computational Biology and Digital Sciences (CBDS), the successful candidate will contribute to oncology drug discovery research through in silico data driven approaches. You will leverage multi-modal omics data analysis and collaborate with biologists to solve scientific challenges to advance drug discovery programs. Duties and responsibilities: Strong scientific understanding and experience in bioinformatics analysis and their implications in disease biology Working knowledge of NGS based omics data analysis (bulk and single cell RNA-seq, spatial transcriptomics analysis is a plus) Identify and process publicly available and internal generated bulk, single-cell and spatial transcriptome datasets using statistical and bioinformatics techniques to create meaningful biological insights Apply and develop innovative analysis approaches when standard methods are not adequate Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field Interpret and present analysis results to coworkers, biologists and collaborators. Communicate work effectively orally and in writing Ensure FAIR data analysis with clear documentation and reproducibility Report and treat data with a high level of integrity and ethics Comply with applicable regulations; Maintain proper records in accordance with SOPs and policies Skills: Programming experience with two or more programming languages including: Python, R for bioinformatic data analysis, shell/bash programming in unix-like systems. Proficiency in working with bulk and single cell NGS data, spatial transcriptomic data analysis is a plus Proficiency in working with cloud computing and high performing clusters (HPC) Experience in biological pathway analysis Experience in applying machine learning and artificial intelligence methods to biological data, deep learning and graph learning is a plus Two years hand on experience of bioinformatic data analysis Solid background in basic biology and disease biology. Knowledge in oncology or immunology is a plus. Ability to develop and benchmark machine learning algorithms Experience in using common public oncology datasets is a plus (TCGA, GTEX, Human cell atlas, CZ CELLxGene Client, Human tumor atlas network, etc) Education: PhD/Master's degree from an accredited institution with experience in a related scientific discipline (Computational Biology, Genomics, Biostatistics, Bioinformatics and Biological Sciences preferred) Required SEQUENCING ARTIFICIAL INTELLIGENCE STATISTICS DATA SCIENCE BIOINFORMATICS Job Type: Contract Pay: $40.00 - $50.00 per hour Schedule: • 8 hour shift Work Location: Remote

Look for more than answers. As a Bioinformatics Engineer, you will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing. This position is in our Bioinformatics Solutions Engineering group, part of the Research and Development organization, in Molecular Genomics & Oncology unit. The team supports genetic/genomic testing in a highly regulated CAP/CLIA laboratory environment primarily using short and long-read sequencing as the basis of evidence. The right candidate will know how to balance innovation, standards, and quality with a practical understanding of when each is appropriate. The Bioinformatics Solutions Engineering group is a cross-functional unit focusing on end-to-end design, develop, document, validation and launching of new high quality diagnostic tests and services for the benefit our patients. This person can work 100% remote and must be located in the US. • Develop, validate, and implement new software applications, databases, processes, and interfaces relating to next-generation sequencing (NGS) data analysis, advanced diagnostic testing development and validation, data quality review, and clinical reporting. • Serve as SME on specific systems/workflows supporting advanced development and high-tier production support. • Participate in resolution of support requests. Regularly report progress and prepare data analyses for internal review • Prepare reports and other communications of technical activities related to business objectives such as product/process development and improvement. • Activities may be focused individual projects or, more usually, assignments as a member of a project team, often working closely with other Software Developers, R&D bench scientists, Genetic Counselors, Operations Scientists, and other technical business partners. 3+ years of experience with a Bachelor's degree or 1+ year with a Master's degree and experience in an industrial or academic setting working with clinical and biological data or equivalent and underlying technologies including bioinformatic methods, database development, query/scripting/programming languages, cloud development, agile methodology, DevOps and other data analysis tools. Preferred Work Experience / Skills: • Bioinformatics tools such as Dragen, bwa, VEP, FastQC, MultiQC, samtools, bedtools • Experience with sequencing data analysis, bioinformatics, variant data analysis • Pipeline workflow management languages: Nextflow (preferred), Cromwell, CWL, etc. • Database: SQL (e.g., postgress, MySQL), understanding of NoSQL databases • Cloud Computing: AWS • Infrastructure management: Terraform, AWS CDK • Programming Languages: Advanced level with interpreted/scripting languages such as Python, javascript/typescript, R, etc. • Containerizing: Docker • Experience with designing and working with application programming interfaces (e.g. JSON based RESTful APIs) • Web Frameworks: Python Flask, React Native, Bootstrap • Reporting: Familiarity with R Markdown, Jupyter Notebook • Visualization: Experience with any of ggplot2/tidyverse, Plotly, matplot lib, Tableau, d3.js • Source Control: Git • CI/CD: Gitlab CI/CD, Github CI/CD • Understanding of environment management • Experience of working in clinical diagnostics setting (regulations, controlled processes, environment management) is a plus. Education: Bachelor’s Degree(Required) Master’s Degree Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets

Current Employees:If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Bioinformatics Analyst (Cheminformatics) to work the UHealth Medical Campus in Miami, FL 33146. CORE JOB SUMMARY The Bioinformatics Analyst works with research staff to extend capabilities in bioinformatics and improve understanding of genetic variation in human health and disease. The Bioinformatics Analyst maintains and performs analysis with existing pipelines while assisting and benchmarking the development of novel methods. CORE JOB FUNCTIONS ● Runs and maintains existing next generation data analysis pipelines. ● Assists senior bioinformatics analysts in pipeline and algorithm development and validation. ● Extracts features of interest from data relating to specific biological questions. ● Contributes to the maintenance of genomic and clinical databases. ● Performs statistical and integrative data analysis on genomics and clinical data. ● Works along-side other team members and data analysts. ● Follows standard operating procedures, documentation, and scripts to generate reports. ● Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS Education: PhD degree in relevant field Experience: Minimum 1 year of relevant experience Knowledge, Skills and Attitudes: ● Skill in collecting, organizing, and analyzing data. ● Ability to recognize, analyze, and solve a variety of problems. ● Ability to exercise sound judgment in making critical decisions. ● Ability to process and handle confidential information with discretion. ● Proficiency in computer software. Department Specific Functions & Qualifications The Sylvester Comprehensive Cancer Center & the Department of Molecular and Cellular Pharmacology are actively seeking a full-time Bioinformatics / Cheminformatics Analyst to work on the UHealth campus in Downtown Miami. At Sylvester, we are at the cutting edge of healthcare innovation, leveraging artificial intelligence and machine learning to transform drug discovery and development. Our mission is to accelerate the delivery of therapeutic solutions to patients through state-of-the-art technology and groundbreaking research. The Analyst will leverage expertise in computational chemistry, bioinformatics, and AI to process and analyze large-scale biomedical, small molecule bioactivity, structural biology, image, and clinicogenomic datasets, integrating them with the Sylvester Data Portal. The successful candidate will work within an interdisciplinary team of research scientists, data engineers, and full-stack developers, using state-of-the-art software development practices to enhance the university’s research activities. Primary Responsibilities: ● Process and analyze large-scale multi-omics and drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Develop and maintain production-grade pipelines for processing and analysis of diverse biomedical datasets. ● Develop visualization and bioinformatic analysis tools for exploring diverse biomedical data. ● Integrate developed tools and pipelines with Sylvester’s internal end-user data analytics platform. ● Apply state-of-the-art AI, bioinformatics, and biostatistics approaches to cancer precision medicine. ● Write standard operating procedures and other relevant documentation. ● Develop and apply AI/ML models for structure-based and ligand-based drug design. ● Utilize computational tools to predict and optimize pharmacokinetic (PK) and pharmacodynamic (PD) properties of drug candidates. ● Design and implement algorithms to identify novel drug candidates and elucidate their mechanisms of action. ● Integrate and analyze large-scale biological, chemical, and clinical datasets to extract insights and inform drug discovery decisions. ● Collaborate with cross-functional teams to advance drug discovery projects. ● Analyze and interpret PK/PD data using advanced statistical and modeling software. ● Stay updated with advancements in computational chemistry, AI, and bioinformatics. ● Contribute to the development of new computational tools and methodologies. ● Present findings to both technical and non-technical stakeholders. ● Participate in scientific discussions and strategy meetings, providing AI/ML expertise. ● Author scientific papers, reports, and patents related to AI/ML in drug discovery. Preferred Requirements ● PhD or MSc degree in computational chemistry, computational biology, medicinal chemistry, pharmaceutical sciences, computational sciences, or a related field. ● Fluency in R or Python and Unix (bash). ● Experience with analyzing and interpreting different omics and/or drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Experience with using common open-source bioinformatics/NGS workflows (BWA, STAR, Picard, GATK, etc.). ● Familiarity with machine learning frameworks (e.g., Scikit-learn, TensorFlow, PyTorch), and developing and deploying machine learning models. ● Highly motivated, strong work ethic, and able to work independently and with a team. ● Excellent skills in communication, organization, and time management. Preferred Qualifications ● For Ph.D. holders: 0-3 years of relevant experience in computational chemistry, AI, and drug discovery. ● Deep expertise with chemical toolkits such as DeepChem, ChemAxon, OEChem, or RDKit. ● Familiarity with drug discovery databases (CTRP, GDSC, PRISM, CCLE, DepMap, LINCS) and publicly available clinicogenomic datasets (CPTAC, TCGA, AACR Project GENIE, etc.). ● Experience with Cloud Computing Environments (e.g., Azure). ● Familiarity with relational (e.g., PostgreSQL) and/or NoSQL databases (e.g., MongoDB). ● Familiarity with container technologies (e.g., Docker). ● Experience with Generative AI tools and techniques. ● Familiarity with High Performance Computing. ● Familiarity with version control (Git). #LI-YC1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A9

Current Employees: If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. Microbiology & Immunology has an exciting opportunity for a full time Research Associate 3, SOM position. The incumbent assumes responsibility for the design and performance of research focused on the development of novel experimental therapies for human malignancies. The incumbent contributes to collaborations with scientists within the University of Miami or elsewhere. Moreover, this individual works as part of a team and assists with the maintenance of laboratory equipment, protocols, and supplies. CORE JOB FUNCTIONS • Maintains daily operations and performs procedures related to new and on-going research projects. • Assists with ordering, purchasing, and maintenance of all required reagents and supplies for laboratory activities, and monitors and maintains inventory of supplies and stocks. • Assists with the maintenance of institutional biosafety and animal care protocols, laboratory safety records, and standard operating procedures. • Performs and assists other research staff with standard laboratory techniques. • Develops, adapts, and implements new laboratory procedures. • Records, organizes, and writes up experimental results for submission of manuscripts and for scientific presentations. • Keeps abreast of latest literature in the field and searches for references to technical problems. • Maintains current knowledge of the methods and techniques related to the specific field of research. • Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS • Bachelor’s Degree in relevant field • Minimum 5 years of relevant experience DEPARTMENT ADDENDUM Department Specific Functions • Design and apply bioinformatics algorithms including unsupervised and supervised machine learning, dynamic programming, or graphic algorithms. • Compile data for use in activities such as gene expression profiling, genome annotation, and structural bioinformatics • Create novel computational approaches and analytical tools as required by research goals • Work with lab team to analyze problems, recommend technology-based solutions, or determine computational strategies. • Create or modify web-based bioinformatics tools and train personnel in technical or scientific procedures. • Prepare scientific or technical reports or presentations #LI-GD1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A7

Current Employees: If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Bioinformatics Analyst (Cheminformatics) to work the UHealth Medical Campus in Miami, FL 33146. CORE JOB SUMMARY The Bioinformatics Analyst works with research staff to extend capabilities in bioinformatics and improve understanding of genetic variation in human health and disease. The Bioinformatics Analyst maintains and performs analysis with existing pipelines while assisting and benchmarking the development of novel methods. CORE JOB FUNCTIONS ● Runs and maintains existing next generation data analysis pipelines. ● Assists senior bioinformatics analysts in pipeline and algorithm development and validation. ● Extracts features of interest from data relating to specific biological questions. ● Contributes to the maintenance of genomic and clinical databases. ● Performs statistical and integrative data analysis on genomics and clinical data. ● Works along-side other team members and data analysts. ● Follows standard operating procedures, documentation, and scripts to generate reports. ● Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS Education: PhD degree in relevant field Experience: Minimum 1 year of relevant experience Knowledge, Skills and Attitudes: ● Skill in collecting, organizing, and analyzing data. ● Ability to recognize, analyze, and solve a variety of problems. ● Ability to exercise sound judgment in making critical decisions. ● Ability to process and handle confidential information with discretion. ● Proficiency in computer software. Department Specific Functions & Qualifications The Sylvester Comprehensive Cancer Center & the Department of Molecular and Cellular Pharmacology are actively seeking a full-time Bioinformatics / Cheminformatics Analyst to work on the UHealth campus in Downtown Miami. At Sylvester, we are at the cutting edge of healthcare innovation, leveraging artificial intelligence and machine learning to transform drug discovery and development. Our mission is to accelerate the delivery of therapeutic solutions to patients through state-of-the-art technology and groundbreaking research. The Analyst will leverage expertise in computational chemistry, bioinformatics, and AI to process and analyze large-scale biomedical, small molecule bioactivity, structural biology, image, and clinicogenomic datasets, integrating them with the Sylvester Data Portal. The successful candidate will work within an interdisciplinary team of research scientists, data engineers, and full-stack developers, using state-of-the-art software development practices to enhance the university’s research activities. Primary Responsibilities: ● Process and analyze large-scale multi-omics and drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Develop and maintain production-grade pipelines for processing and analysis of diverse biomedical datasets. ● Develop visualization and bioinformatic analysis tools for exploring diverse biomedical data. ● Integrate developed tools and pipelines with Sylvester’s internal end-user data analytics platform. ● Apply state-of-the-art AI, bioinformatics, and biostatistics approaches to cancer precision medicine. ● Write standard operating procedures and other relevant documentation. ● Develop and apply AI/ML models for structure-based and ligand-based drug design. ● Utilize computational tools to predict and optimize pharmacokinetic (PK) and pharmacodynamic (PD) properties of drug candidates. ● Design and implement algorithms to identify novel drug candidates and elucidate their mechanisms of action. ● Integrate and analyze large-scale biological, chemical, and clinical datasets to extract insights and inform drug discovery decisions. ● Collaborate with cross-functional teams to advance drug discovery projects. ● Analyze and interpret PK/PD data using advanced statistical and modeling software. ● Stay updated with advancements in computational chemistry, AI, and bioinformatics. ● Contribute to the development of new computational tools and methodologies. ● Present findings to both technical and non-technical stakeholders. ● Participate in scientific discussions and strategy meetings, providing AI/ML expertise. ● Author scientific papers, reports, and patents related to AI/ML in drug discovery. Preferred Requirements ● PhD or MSc degree in computational chemistry, computational biology, medicinal chemistry, pharmaceutical sciences, computational sciences, or a related field. ● Fluency in R or Python and Unix (bash). ● Experience with analyzing and interpreting different omics and/or drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Experience with using common open-source bioinformatics/NGS workflows (BWA, STAR, Picard, GATK, etc.). ● Familiarity with machine learning frameworks (e.g., Scikit-learn, TensorFlow, PyTorch), and developing and deploying machine learning models. ● Highly motivated, strong work ethic, and able to work independently and with a team. ● Excellent skills in communication, organization, and time management. Preferred Qualifications ● For Ph.D. holders: 0-3 years of relevant experience in computational chemistry, AI, and drug discovery. ● Deep expertise with chemical toolkits such as DeepChem, ChemAxon, OEChem, or RDKit. ● Familiarity with drug discovery databases (CTRP, GDSC, PRISM, CCLE, DepMap, LINCS) and publicly available clinicogenomic datasets (CPTAC, TCGA, AACR Project GENIE, etc.). ● Experience with Cloud Computing Environments (e.g., Azure). ● Familiarity with relational (e.g., PostgreSQL) and/or NoSQL databases (e.g., MongoDB). ● Familiarity with container technologies (e.g., Docker). ● Experience with Generative AI tools and techniques. ● Familiarity with High Performance Computing. ● Familiarity with version control (Git). #LI-YC1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A9

Current Employees: If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. The University of Miami/UHealth Department of SCCC has an exciting opportunity for a full time Sr. Bioinformatics Analyst to work in the UHealth Medical campus in Miami, FL. The Senior Bioinformatics Analyst works with research staff to extend capabilities in bioinformatics and improve understanding of genetic variation in human health and disease. The Senior Bioinformatics Analyst also assumes responsibility for the development and maintenance of novel bioinformatics methods. CORE JOB FUNCTIONS 1. Develops and maintains next generation data analysis pipelines. 2. Assists in analysis pipeline and algorithms development and validation. 3. Extracts features of interest from data relating to specific biological questions. 4. Contributes to the development and maintenance of genomic and clinical databases. 5. Performs statistical and integrative data analysis on genomics and clinical data. 6. Supervises team members and other data analysts. 7. Establishes standard operating procedures, documentation, and scripts to generate custom reports. 8. Progresses material for bioinformatics tutorials and training courses. 9. Tests the characterization and integration of diverse third-party bioinformatics algorithms. 10. Adheres to University and unit-level policies and procedures and safeguards University assets. Department Specific Functions: As a Sr. Bioinformatics Analyst, you will be responsible for the bioinformatics and data analytics needs of the PSR. • Be actively involved in mass-spectrometry based proteomics data generation, processing, quality assurance analytics and visualization. • Organize, maintain, and version control FASTA formatted databases for protein and peptide ID searches. • Manipulate RNA-seq data for searching against mass spectrometry-based protein and peptide mass and intensity data. • Perform searches to translation m/z and intensity data in the amino acid sequence information and assemble that data into protein-based results. • Perform statistical analysis on label free quantitation, SILAC, and mass barcode (TMT) results to generate volcano plots and results in other visualization space(s). This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS Education: Bachelor’s Degree in relevant field. Master’s or PhD preferred in bioinformatics, applied mathematics, or large data analysis. Experience: Minimum 3 years of relevant experience Knowledge, Skills and Attitudes: • Skill in collecting, organizing, and analyzing data. • Ability to recognize, analyze, and solve a variety of problems. • Ability to exercise sound judgment in making critical decisions. • R-scripting and/or pearl scripting skills required. • Exceptional computer skills. • Excellent written and verbal communication skills. • Proficiency in MaxQuant, Sequest, Mascot, and Proteome Discoverer software tools. • Self-starter, diligent individual contributor, as well as delightful to work in a team environment. • Desire to apply proteomics towards improving quality of life and improving cancer diagnosis and care. • A strong publication record is desired but not required. #LI-YC1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A11