Bioinformatics Jobs

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years. BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation. Our team has grown significantly and despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com. We are looking for a Bioinformatics Associate, Prenatal to join our Clinical Operations team to create computational tools to analyze groundbreaking molecule diagnostics. This person will be responsible for developing bioinformatics pipelines and analyzing next-generation DNA sequencing data under the guidance of bioinformatics scientists. This is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. The Bioinformatics Associate role is a full-time onsite position in Menlo Park, CA. Responsibilities: • Develop sophisticated and robust next-generation sequencing analysis pipelines under the guidance of a senior scientist • Perform analysis of clinical bioinformatics data • Assemble and analyze quality metrics from the clinical laboratory • Maintain analysis pipeline and operational tools using DevOps practices • Collaborate with scientists and support new scientific insights Requirements: • BS or MS in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related field • 1-2 years of biology research experience (either during BS/MS or afterwards) • Strong programming skills in Python, R or a similar language, especially with application to complex data processing and transformation • Strong communication skills and ability to collaborate with interdisciplinary teams • Coursework or experience with molecular biology laboratory techniques and human genetics • High mathematical and statistical aptitude • Great attention to detail Nice-To-Haves: • Software Engineering experience, particularly with DevOps best practices • Experience with clinical laboratory operations • 1-2 years of research experience • Molecular biology (DNA purification, PCR, electrophoresis) or next-generation DNA sequencing laboratory experience Benefits And Perks: • Working with a team of ‘rockstars’ who bring out the best in everyone • Open, transparent culture that includes weekly Town Hall meetings • The ability to indirectly or directly change the lives of hundreds of thousands patients • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80% • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%) • Retirement savings program including a 4% Company match • Free daily on-site lunches provided from top eateries • Latest and greatest hardware (laptop, lab equipment, facilities) • A variety of perks on campus (state of the art gym, restaurant) • Free on-site EV charging (compatible with all EVs, including Tesla) At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.). For this position, we offer a total compensation package of $98,010 per year, including a base pay range of $71,400-$81,600 per year. BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. For more information about how we protect your information, we encourage you to review our Privacy Policy.

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description Product Specialist Bioinformatics As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. Location/Division Specific Information Product Specialist Bioinformatics, Clinical Sequencing Division Onsite role Discover Impactful Work This Bioinformatics Product Specialist role provides an outstanding opportunity for a Bioinformatician with a curiosity about working in product support at a global level to deliver outstanding data analysis support for next-generation sequencing platforms. This role is uniquely positioned within the product management team and provides insight to the product roadmap. In this role, you will work as a vital link between customers, field support teams, software product managers and internal bioinformatics development teams to resolve issues related to the usage of software products and interpretation of results. If you have experience of working in the biotechnology industry in a technical or customer support role or have meaningful experience in academia, this is an excellent opportunity to build on your current abilities and learn about how genomics labs across the world analyze next-generation sequencing data. A Day in the life • Work with our global field support colleagues to help our customers with their software and bioinformatics challenges, with an emphasis on gene panel sequencing. This may include troubleshooting, problem-solving, customizing analysis pipelines to resolve issues and present data in the best light • Act as a link between the field teams and internal development teams to identify and resolve advanced customer cases • Capture feedback from customers to help the product management team prioritize requirements for future hardware and software development • Build training materials and run training sessions for our field teams. • Develop a deep understanding of our software analysis pipelines, algorithms and system set up • Participate in reviewing pre-release software Keys to Success Education • BS required in bioinformatics, molecular biology, biochemistry, computer science or equivalent, Masters or PhD (preferred) Experience • Minimum 3 years of confirmed experience in bioinformatics and data analysis. Practical experience with open-source bioinformatics tools and wide knowledge of genomics applications are especially useful • Previous experience in data analysis of next-generation sequencing data is required Knowledge, Skills and Abilities • Ability to present bioinformatics issues and solutions to audiences with varying levels of experience is critical. • Previous experience working with clinical NGS lab customers would be a distinct advantage. • Previous experience using Linux and writing scripts or other code would be an advantage • Looking for a self-starter who is comfortable working in a fast-paced interdisciplinary team Compensation and Benefits The salary range estimated for this position based in California is $100,000.00–$133,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: • A choice of national medical and dental plans, and a national vision plan, including health incentive programs • Employee assistance and family support programs, including commuter benefits and tuition reimbursement • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

About Us Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform. Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike. Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company. Summary of Position The Director of Bioinformatics leads a team of experts in bioinformatics and biostatistics in the planning, designing, and implementing bioinformatics infrastructure to address clinical diagnostics production, R&D, and client needs. The Director formulates strategic plans for bioinformatics solutions, working closely with other team leads and executive leadership. The Director serves as the expert and champion of bioinformatics, strongly emphasizing innovation and development of best-in-class bioinformatics solutions. Key Job Elements • Direct the planning, designing, development, implementation, and maintenance of the bioinformatics infrastructure, including data, hardware and software components, and system integration. • Oversee bioinformatics production, R&D, and client service efforts. • Provide the organization with short-term and long-term bioinformatics strategic plans to meet business objectives. • Direct a team of bioinformatics scientists in developing bioinformatics infrastructure, R&D, and client service. • Develop and deploy novel bioinformatics analyses and tools. • Monitor, review, and utilize emerging technologies. • Serve as bioinformatics subject matter expert to cross-functional teams. • Direct resolution of bioinformatics production issues. • Review and provide feedback on design, validation, testing methodology, documentation, and reports • Provide advice, guidance, and mentoring to bioinformatics staff. • Build and manage a staff of bioinformatics professionals. Knowledge/Experience • Master’s or Ph.D. in Bioinformatics, Computer Science, or related field. • 7-10 years of experience in related Bioinformatics. • Extensive hands-on and in-depth experience with next-generation sequencing (NGS) analysis, NGS databases and tools, and NGS pipeline development. • Extensive experience analyzing multiple types of NGS data and facility with statistics for big data analysis and multi-omics data integration. • Extensive experience in designing, developing, implementing, and managing NGS analysis pipelines and workflows. • Experience leading bioinformatics development teams. • Strong hands-on skills in relevant programming languages. • Must enjoy working in a multi-disciplinary and collaborative environment and leading and mentoring a bioinformatics team. • Excellent oral and written skills, including the ability to communicate openly, transparently, in a timely, and consistent manner. Supervisory Responsibilities • Yes Reports To • Chief Operating Officer Environment Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term “qualified individual with a disability” means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position. For California residents, please see the link below to access our CCPA Privacy Notice. CCPA Privacy Notice for California Residents https://tinyurl.com/FulgentCCPA Agency Solicitations Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question — that choose to submit a resume or client information to our career page or to any employee of Fulgent — will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.

Description The Semel Institute is seeking to hire a full time Bioinformatics Programmer 2 who will assist in computational and statistical analyses in multiple projects in the lab, including maintenance of our next-generation sequencing pipelines using languages such as Python, PERL, R and Bash scripting. In this role you will work closely with lab members to integrate transcriptomics with genomics and epigenomics to better understand how genes work together at a quantitative and systems biology level to alter risk for neurodegenerative and neuropsychiatric disorders. This will include, but not be limited to, managing large genomic data sets across multiple computational resources including cloud services such as Amazon Web Services; support record-keeping in database systems such as MySQL; and analyzing data related to brain development and autism from human and animal models. Background in genetics or bioinformatics is highly desirable. Pay Range: $36.49 - 76.05

Situated in Stanford’s highly dynamic research environment the Curtis Laboratory (http://med.stanford.edu/curtislab.html), led by Christina Curtis, PhD, is seeking a bioinformatician/Research Data Analyst 1 to join the Cancer Computational and Systems Biology group. The Curtis Laboratory is administratively situated within the Stanford Cancer Institute and is integrated within Stanford University and the School of Medicine’s Departments of Medicine (Oncology) and Genetics. The SCI is part of a Comprehensive National Cancer Institute Cancer Center for cross-disciplinary research in cancer biology involving researchers from oncology, radiobiology, computer science, genetics, statistics, and basic/translational clinical research. Our research couples state-of-the-art computational and experimental techniques to define novel therapeutic targets and biomarkers and to characterize tumor evolution. The successful candidate will be part of an interdisciplinary research team developing novel technological and methodological approaches to improve the diagnosis, treatment and earlier detection of cancer. He/she will analyze and interpret large sequencing datasets by applying and developing bioinformatics and statistical methods for whole genome/exome sequencing, RNA-seq, ATAC-seq, single cell and spatial datasets. The successful candidate will interact closely with other computational and experimental biologists and clinicians to test, validate, and refine hypotheses. This is a fantastic opportunity for a motivated bioinformatician or computational genomicist to join a dynamic team with significant opportunities for scholarship. Duties include: • Collect, manage and clean datasets. • Employ new and existing tools to interpret, analyze, and visualize multivariate relationships in data. • Create databases and reports, develop algorithms and statistical models, and perform statistical analyses appropriate to data and reporting requirements. • Use system reports and analyses to identify potentially problematic data, make corrections, and determine root cause for data problems from input errors or inadequate field edits, and suggest possible solutions. • Develop reports, charts, graphs and tables for use by investigators and for publication and presentation. • Analyze data processes in documentation. • Collaborate with faculty and research staff on data collection and analysis methods. • Provide documentation based on audit and reporting criteria to investigators and research staff. • Communicate with government officials, grant agencies and industry representatives. • - Other duties may also be assigned DESIRED QUALIFICATIONS: • Bachelor’s degree (or higher) in Bioinformatics, Computer Science or a related field with one year (min) of relevant experience • Strong background in bioinformatics and biostatistics, including analysis of high-throughput sequencing data • Experience working within a UNIX/Linux environment • Fluency in programming languages such as Perl, Python, Java, R, C, Matlab; MySQL • Excellent communication and team skills and fluency in both spoken and written English • Familiarity with machine learning, information theory and signal processing. • Experience with algorithm development • Familiarity with basic molecular biology • Background in cancer biology EDUCATION & EXPERIENCE (REQUIRED): Bachelor's degree or a combination of education and relevant experience. Experience in a quantitative discipline such as economics, finance, statistics or engineering. KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED): • Substantial experience with MS Office and analytical programs. • Strong writing and analytical skills. • Ability to prioritize workload. PHYSICAL REQUIREMENTS*: • Sitting in place at computer for long periods of time with extensive keyboarding/dexterity. • Occasionally use a telephone. • Rarely writing by hand. • - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job. WORKING CONDITIONS: Some work may be performed in a laboratory or field setting. WORK STANDARDS: • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations. • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned. • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu. The expected pay range for this position is $82,468 to $106,256 per annum. Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs. At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process. Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources by submitting a contact form. Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

You will be part of the Software Development and Analytics team supporting the development of the Next Generation Sequencing cloud applications. You will complete a deep dive into antibody data en route to developing an antibody ranking algorithm. You will be assigned a mentor and work within one of the functional disciplines in the Computational Biology organization. Come join us as part of our internship program in our next breakthrough product. At our Pleasanton R&D center, you can have big company impact while working at a small, nimble and dynamic site. How You’ll Make An Impact: • Apply data science methods and algorithms to profile antibodies and provide useful information to researchers. • Design, code, and test a new antibody algorithm for NGS cloud products. • Work with Bioinformatics sub-team to coordinate development of new features and resolve issues. • Present data from capstone project to a broad audience. What You Bring: • Education: Sophomore or junior university student in Computer Engineering/Computer Science/Bioinformatics. • Excellent interpersonal/communication skills. • Ability to work independently and as part of a wider team. • Experience coding Python. • Experience working in a unix environment. • Experience with common bioinformatics tool Total Rewards Package: At Bio-Rad, we’re empowered by our purpose and recognize that our employees are as well. That’s why we offer a competitive and comprehensive Total Rewards Program that provides value, quality, and inclusivity while satisfying the diverse needs of our evolving workforce. Bio-Rad's robust offerings serve to enrich the overall health, wealth, and wellbeing of our employees and their families through the various stages of an employee’s work and life cycle. Benefits: We’re proud to offer a variety of options, including competitive medical plans for you and your family, free HSA funds, a new fertility offering with stipend, group life and disability, paid parental leave, 401k plus profit sharing, an employee stock purchase program, a new upgraded and streamlined mental health platform, extensive learning and development opportunities, education benefits, student debt relief program, pet insurance, wellness challenges and support, paid time off, Employee Resource Groups (ERG’s), and more! Compensation: The estimated hourly range for this position is $25 at the time of posting. Actual compensation will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. Who We Are: For 70 years, Bio-Rad has focused on advancing the discovery process and transforming the fields of science and healthcare. As one of the top five life science companies, we are a global leader in developing, manufacturing, and marketing a broad range of high-quality research and clinical diagnostic products. We help people everywhere live longer, healthier lives. Bio-Rad offers a unique employee experience with collaborative teams that span the globe. Here, you are supported by leadership to build your career and are empowered to drive change that makes an impact you can see. EEO Statement: Bio-Rad is an Equal Employment Opportunity/Affirmative Action employer, and we welcome candidates of all backgrounds. Veterans, people with physical or mental disabilities, and people of all race, color, sex, sexual orientation, gender identity, religion, national origin and citizenship status are encouraged to apply. Agency Non-Solicitation: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Recruiting Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes. Fraud Alert: Bio-Rad has received reports of individuals posing as Bio-Rad recruiters to obtain information, including personal and financial, from applicants. Beware of these fake "recruiters" and job scams. Click here for more information on this scam and how to avoid it. Legal Entity: (USA_1000)Bio-Rad Laboratories, Inc.

Job Summary: Zymo Research is seeking a highly motivated Research Intern to join our dynamic Microbiomics team. This is an exciting opportunity for someone interested in exploring cutting-edge technologies and applications in the fields of microbiome Next Generation Sequencing and research. As a Bioinformatics Intern, you will be mentored by industry veterans from our Microbiomics R&D group. The qualified individual will be responsible for initiating and completing assigned tasks throughout the duration of the internship. In this role, you will work collaboratively with other team members to design and execute infrastructures for a developing bioinformatics product. The ideal candidate should be flexible, an effective team player, and possess a strong interest in learning about bioinformatic applications for microbiomics and next generation sequencing. The successful candidate should also have some experience in microbiology and fundamental molecular biology laboratory processes. If you are passionate about helping people in advancing science and working with awesome teams in a fast-growing company, we want you! This position is a full-time Internship and is based in Irvine, CA. Essential Duties and Responsibilities • Assist with the curation of human microbiome data studies by finding, organizing, and independently processing them through a standardized workflow. • Work collaboratively in a team-based environment to provide feedback and recommendations for project advancement. • Assist with creating visual representations and user stories for platform features. • Review, summarize, and apply relevant literature to project goals as needed. • Aid in the writing and summarization process of project goals to outside parties. Education and Experience: • Working towards, or having completed, a BS or MS in Biology, Microbiology, Biochemistry, Genetics, or related field with an interest in Bioinformatics. Preferably junior or senior standing at an accredited university, with some bioinformatics application experience. Recent graduates are also encouraged to apply. • Basic understanding of microbiome research processes and the application of Next Generation Sequencing fundamentals. • Knowledge of Microsoft Office products. About Us: Since its inception in 1994, Zymo Research has been proudly serving the scientific community by providing innovative, reliable, and high-quality research tools and products. Whether it's DNA, RNA, epigenetics, microbiomics, protein, or yeast-based research, our philosophy remains the same: To provide the highest quality products in the industry while ensuring they are both simple to use and reliable in their performance. Recognized as a Top Workplace by the Orange County Register in 2021, 2022, and named a Top Workplace USA in 2023, Zymo Research continues to be a vibrant community where employees thrive, feel connected, and are inspired by their work. If you are passionate about contributing to scientific advancement and want to be part of an exceptional team in a dynamic, growing company, we'd love to hear from you! Compensation: The estimated base compensation range for this position is $20/hour at the time of posting. Actual compensation details will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. Equal Employment Opportunity Employer: Zymo Research welcomes candidates of all backgrounds. These include sex, age, color, race, religion, marital status, national origin, ancestry, sexual orientation, gender, gender identity, gender expression, physical & mental disability, medical condition, genetic information, military and veteran status, or any other protected status as defined by federal, state, or local law. Location: Onsite – Zymo Research HQ, 17062 Murphy Ave. Irvine, CA 92614 Apply Now

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Eli Lilly and Company is committed to developing medicines and identify novel targets to improve outcomes for patients. Lilly has invested in autoimmunity and immunology research and development. We have a robust pipeline covering novel targets and mechanisms, mid- and late-stage potential treatments and approved medicines for a variety of autoimmune indications. These new therapies align with our corporate strategy to commercialize first-in-class and best-in-class treatments to address unmet medical needs. In support of these goals, bioinformatics scientists deliver biologically, and clinically testable hypotheses based on systematic analyses of proprietary and public clinical and pre-clinical data. This is achieved through a) deep knowhow of specialized biological databases, b) expertise in developing and applying genetics and ‘omics data from multiple platforms, and c) application of integrative analysis approaches. The overarching objective is to improve knowledge around the targets, pathways, and molecular basis/heterogeneity of disease so that we can design better potential medicines and identify patients that are more likely to respond to particular treatments. The bioinformatics scientist operates in a dynamic and cross functional environment, working closely with discovery scientists, clinical researchers, computational scientists and statisticians to enable research related to drug discovery and identification of biomarker with a specific focus on autoimmune diseases. All informatics work is done in a “reproducible research” environment. The candidate will be expected to share best practices with others and also be willing to adopt new methods. This entails using molecular profiles and multiple internal and external biomedical databases to help understand disease heterogeneity and then to leverage it to enable research related to drug discovery and helping define relevant patient populations. Key responsibilities • Collaborate with discovery biologists, clinical researchers/physicians, and statisticians to enable various aspects of drug/biomarker discovery or development in support of the autoimmune portfolio deliverables, beginning from novel target discovery, all phases of clinical trials, to post launch. • Propose, conduct analysis, and provide interpretation in support of key project aims. • Present results and provide scientific reports as needed or requested by the project teams as a component of project reviews, milestones or governance in a manner fit for cross-functional team consumption. • Use internal and external data sources such as but not limited to genome variation, genotype-phenotype association, molecularly characterized disease state databases, etc., to routinely deliver assimilated information and insights relating to target of interest or pathway of interest, appropriateness of pre-clinical models, mechanistic understanding in perturbation studies, biomarkers supporting pharmacodynamics or efficacy and hypothesis relating to patient stratification. • Participate in the evaluation and identification of new vendors, services, platforms in genomics arena for eventual application for scientific investigations such as (but not limited to) disease characterization or diagnostic applications. • Leverage internal expertise in informatics from other therapeutic areas, advanced analytics and statistics. • Collaborate closely with others around data analysis methods and application. • Represent Immunology in external collaborations with both academic centers and commercial companies. • Provide analysis or related support as needed in context of such collaborations. • Facilitate bringing in data/knowhow or learning into the broader organization. • Contribute to external scientific community through presentations and participation in appropriate scientific conferences and journal publications. Requirements • PhD degree or equivalent in medicine, biology, computational or statistical sciences with at least 5 years of relevant bioinformatics experience in the pharmaceutical field. • Experience with Single Cell Sequencing • Experience with Genetics or Genetics background Additional Skills / Preferences • Statistics experience is preferred. • Experience working with Clinical Trials • Highly familiar with biological research related to one or more disease and related areas in autoimmune disorders and the desire to continue learning. • Ability to interpret and effectively communicate the findings of omics level data with collaborators that are meaningful to the team. • Hands-on experience of quality control and analyzing data generated using many of the following a) genetic analysis, b) single cell approaches, c) spatial omics, d) proteomics and, e) methylation, with emphasis on biological interpretation. Familiarity with multiple genomics platforms from vendors such as 10x Genomics, Illumina, etc. around applications such as WGS, RNA-Seq and ChIP-Seq, DNA Methylation and Genotyping. • Experience in applying computational systems biology or integrative analysis approaches to facilitate interpretation and hypothesis generation from results of genetics, genomics, proteomics and epigenetics studies, preferably in a cross functional setting. Ability to rapidly prototype novel methods for suitable scientific problems. • Experience in novel target discovery and validation, biomarker discovery, mechanisms of action of drugs candidates, and correlating genomic/genetics data with clinical and biochemical phenotypes. Proven ability to provide testable hypotheses to project teams based on systematic analysis of data from pre-clinical and clinical samples. • Expertise in a range of biological databases and use for translational or basic research. Experience with publicly and commercially available bioinformatics pathway/network analysis tools, genomics and genetics databases. Good bioinformatics programming skills in scripting or programming languages and related bioinformatics packages. Experience working in a high-performance unix cluster, Nextflow, and a cloud-based environment. • Demonstrated ability to develop and use the tools in the “reproducible research” environment using Rmarkdown, R, dplyr, jupyter, and python. Strong coding skills are a key requirement in this position as all analysis is done in this environment. Expertise in collaborative software developments such at Github. • Previous wet lab experience. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $184,500 - $321,200 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description Work Schedule Standard (Mon-Fri) Environmental Conditions Office Do you have a passion for innovative ideas and groundbreaking discoveries?With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you’ll help solve some of the world’s toughest challenges, from giving cancer patients hope, ensuring safe drinking water, and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources, and tools they need to take science a step beyond. Discover Impactful Work: As a Staff Scientist, Bioinformatics, you will support the development and implementation of Next Generation Sequencing (NGS) based oncology assays within the Clinical Sequencing Division. You will leverage your expertise in oncology bioinformatics, Python programming, and Unix/Linux systems to develop and maintain bioinformatics pipelines, analyze complex genomic data, and ensure compliance with regulatory standards. Your work will directly contribute to advancing precision medicine and improving patient outcomes. A day in the Life: • Pipeline Development and Maintenance:Develop, optimize, and maintain bioinformatics pipelines and tools using Python and other relevant scripting languages on linux based platforms. • Data Analysis:Perform data analysis and interpretation of high-throughput sequencing data, including but not limited to DNA, RNA, cell free total nucleic acid datasets. • Collaboration:Work closely with cross-functional teams, including laboratory scientists, clinical researchers, regulatory professionals, and software developers, to design and implement bioinformatics solutions that meet project requirements. • Troubleshooting:Troubleshoot and resolve technical issues related to data processing and analysis, ensuring timely and accurate results. • Quality Control:Ensure data integrity, quality control, and compliance with regulatory standards throughout the development process. • Documentation:Document workflows, pipelines, and analysis results in a clear and reproducible manner, adhering to best practices in scientific research. • Continuous Learning:Stay up-to-date with the latest developments in bioinformatics, genomics, and computational biology, and apply this knowledge to improve existing pipelines and develop new solutions. Keys to Success: Education • Ph.D. or Master’s degree in Bioinformatics, Computational Biology, Molecular Biology, or a related field. Experience • At least 5 years of experience in bioinformatics, with a focus on oncology and Next Generation Sequencing (NGS). • Proven experience in Python programming, bash scripting, Unix/Linux systems, next generation sequencing analysis, and somatic oncology genomics • Strong understanding of bioinformatics tools and algorithms, including sequence alignment, variant calling, and functional annotation. • Experience with high-throughput sequencing data analysis (e.g., NGS, RNA-Seq, WGS, etc.). • Familiarity with version control systems (e.g., Github) • Experience working in regulated environments and familiarity with regulatory compliance and quality assurance standards. Knowledge, Skills, Abilities • Outstanding problem-solving skills and attention to detail. • Strong communication and collaboration skills, with the ability to work effectively in a multidisciplinary team. • Excellent documentation skills, with the ability to write clear and reproducible workflows. • Familiarity with cloud data platforms (e.g., AWS) and containerization technologies (e.g., Docker) is a plus. • Knowledge of statistical analysis and machine learning techniques is a plus. • Familiarity with databases and data management systems (e.g., SQL, NoSQL) is a plus. We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits.Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation! Apply today!http://jobs.thermofisher.com Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. Compensation And Benefits The salary range estimated for this position based in California is $118,500.00–$177,850.00 This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: • A choice of national medical and dental plans, and a national vision plan, including health incentive programs • Employee assistance and family support programs, including commuter benefits and tuition reimbursement • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount Compensation and Benefits The salary range estimated for this position based in California is $118,600.00–$177,850.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: • A choice of national medical and dental plans, and a national vision plan, including health incentive programs • Employee assistance and family support programs, including commuter benefits and tuition reimbursement • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Look for more than answers. As a Bioinformatics Engineer, you will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing. This position is in our Bioinformatics Solutions Engineering group, part of the Research and Development organization, in Molecular Genomics & Oncology unit. The team supports genetic/genomic testing in a highly regulated CAP/CLIA laboratory environment primarily using short and long-read sequencing as the basis of evidence. The right candidate will know how to balance innovation, standards, and quality with a practical understanding of when each is appropriate. The Bioinformatics Solutions Engineering group is a cross-functional unit focusing on end-to-end design, develop, document, validation and launching of new high quality diagnostic tests and services for the benefit our patients. This person can work 100% remote and must be located in the US. • Develop, validate, and implement new software applications, databases, processes, and interfaces relating to next-generation sequencing (NGS) data analysis, advanced diagnostic testing development and validation, data quality review, and clinical reporting. • Serve as SME on specific systems/workflows supporting advanced development and high-tier production support. • Participate in resolution of support requests. Regularly report progress and prepare data analyses for internal review • Prepare reports and other communications of technical activities related to business objectives such as product/process development and improvement. • Activities may be focused individual projects or, more usually, assignments as a member of a project team, often working closely with other Software Developers, R&D bench scientists, Genetic Counselors, Operations Scientists, and other technical business partners. 3+ years of experience with a Bachelor's degree or 1+ year with a Master's degree and experience in an industrial or academic setting working with clinical and biological data or equivalent and underlying technologies including bioinformatic methods, database development, query/scripting/programming languages, cloud development, agile methodology, DevOps and other data analysis tools. Preferred Work Experience / Skills: • Bioinformatics tools such as Dragen, bwa, VEP, FastQC, MultiQC, samtools, bedtools • Experience with sequencing data analysis, bioinformatics, variant data analysis • Pipeline workflow management languages: Nextflow (preferred), Cromwell, CWL, etc. • Database: SQL (e.g., postgress, MySQL), understanding of NoSQL databases • Cloud Computing: AWS • Infrastructure management: Terraform, AWS CDK • Programming Languages: Advanced level with interpreted/scripting languages such as Python, javascript/typescript, R, etc. • Containerizing: Docker • Experience with designing and working with application programming interfaces (e.g. JSON based RESTful APIs) • Web Frameworks: Python Flask, React Native, Bootstrap • Reporting: Familiarity with R Markdown, Jupyter Notebook • Visualization: Experience with any of ggplot2/tidyverse, Plotly, matplot lib, Tableau, d3.js • Source Control: Git • CI/CD: Gitlab CI/CD, Github CI/CD • Understanding of environment management • Experience of working in clinical diagnostics setting (regulations, controlled processes, environment management) is a plus. Education: Bachelor’s Degree(Required) Master’s Degree Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets