Bioinformatics Jobs

Invitae is a healthcare technology company that uses genetic information to empower doctors and patients to make informed medical decisions. Our development team is taming the chaos of biology with cutting-edge methods and high throughput workflows capable of processing thousands of samples each week. We are constantly improving our tools and technologies to deliver the highest quality actionable... information to patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers. As part of our Bioinformatics Rapid Response team you will help improve our products, workflows and tools in a production setting. You will apply your knowledge of software engineering, computer science and statistics to optimize our assays in various ways such as cost, turnaround time and operational stability. In the team, you will drive execution and own a solution through conception, implementation, validation and production release. You will work and learn among an extraordinary set of peers: bioinformaticians, molecular biologists, and software engineers. Your work will improve the quality of our products and directly impact each of our patients. What you will do: • Evaluate and improve production algorithms and statistical models for NGS and non-NGS assays technologies, to reduce costs, improve turnaround time, increase automation • Critically analyze large production datasets using in-house tools and build custom tools when needed • Write production-level code to implement data-driven improvements • Lead development in a cross-disciplinary setting to define issues, assemble datasets, devise analyses and document conclusions for internal review and regulatory purposes What you will bring: • Advanced graduate degree in bioinformatics, statistics, computer science or a related discipline, or 5+ years of experience working in a bioinformatics role • Deep knowledge and experience analyzing genetics data (including Illumina SBS, PacBio, microarrays, capillary electrophoresis) • Understanding of the statistical and algorithmic foundations of modern variant calling packages such as GATK and techniques for CNV/large events calling • Experience reading and writing source code for large software projects, with strong preference for Python • Excellent written and verbal communication and data presentation skills At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. #LI-Remote #LI-JM1

The New York Genome Center (NYGC) is looking for a highly motivated individual to join our computational biology group. As a Bioinformatics Scientist, you will be responsible for the analyses and interpretation of cancer genome samples sequenced at NYGC. This includes the maintenance, benchmarking, and continuous improvement of our analysis pipelines, as well as participation in downstream... analyses by applying existing tools and algorithms to analyze cancer sequencing data, collaborating with NYGC staff to develop new tools and with external investigators on the integration of genomics results within their scientific projects. This position will report to the Director of Computational Biology. Job duties will include, but are not limited to: • Contribute to setup, management and maintenance of genomic data analysis pipelines. • Analyze sequencing data using the established pipeline(s) either already in place at NYGC or state-of-the-art workflows developed by others. • Develop and implement innovative computational approaches for the analysis of large sequence datasets from NGS technologies. • Assist, collaborate and consult with external and internal researchers on the analyses and interpretation of cancer NGS data. • Interpret and present the results of the computational and statistical analyses to collaborators and coworkers. • Collaborate with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager. • Mentor Bioinformatics Analysts and Programmers. • Help identify relevant funding opportunities interests and participate in grant writing. • Publish developed methods and scientific findings in scientific journals and give presentations at conferences. • Participate in community outreach. • Stay current on innovations in DNA sequencing technologies and analyses. Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time. Required Experience • PhD. in bioinformatics, computational biology, genetics, computer science or similar required, or master’s degree plus 5 year’s work experience. • Experience in cancer genomics required. • Experience managing and working with next generation sequencing data required. • Extensive knowledge and experience in the use of existing bioinformatics tools and biological databases. • Excellent written and verbal communication skills required. • Experience with cloud computing environments (optional). • Programming skills required; proficiency in python and R required, as well as willingness to learn new programming languages as necessary. • Experience working in Linux and running tasks in a cluster environment (e.g., SGE) required. • Experience working in teams centered around a biological question and with external collaborators required. Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments. • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity Diversity, equity, and inclusion are central to the core mission at the NYGC. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. FLSA Status – Exempt This position is eligible for visa sponsorship and relocation assistance

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and... volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Prevail Therapeutics is a wholly owned subsidiary of Eli Lilly and Company and is based in New York City. We are leaders in developing gene therapies for Parkinson’s disease, dementias and other genetically defined neurodegenerative diseases. Organization Overview: We are seeking a Research Engineer (Bioinformatics) to help design and engineer our next generation of gene therapy products. You will use provide broad bioinformatics and analytical support for our Research and Manufacturing teams. You will work on innovative computational genomics projects that address challenges in gene therapy, genome editing and neurodegeneration. We seek an entrepreneurial and self-motivated individual who can function with a high degree of independence and work collaboratively within a multidisciplinary team that is dedicated to the development of new therapies for neurodegenerative diseases. Responsibilities: The successful candidate will work across all Prevail functional teams to: • Implement NGS sequencing data analyses to support R&D and AAV manufacturing. • Perform comparative DNA sequence analyses and implement computational tools for designing siRNAs, CRISPR gRNAs and CDS optimization. • Support statistical analyses, maintain databases/portals for Prevail studies and develop R/Shiny tools for interactive visualization • Leverage and integrate large public databases to support pipelines and programs Basic Requirements: • BS in scientific discipline with 2+ years of experience in bioinformatics or MS in Bioinformatics/related field Additional Preferences: • Proficiency in at least one major scripting language (Python, Perl or similar). • Strong understanding of human genetics, and NGS data analysis is required. • Excellent organizational skills and attention to detail; strong interpersonal, planning, and communication skills. Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com

Job Code and Payroll Title 009401 BIOINFORMATICS PROGR 3 Job Summary... The Bioinformatics Programmer position involves establishing pipelines using existing computer algorithms for the analysis of RNA, DNA and TCR sequencing as well as Cytof data. The position will also involve developing new algorithms and pipelines as needed, commencing with but not limited to single cell RNA and TCR sequencing of immune cells from immunotherapy-treated and untreated cancer patients. The candidate will be expected to make independent and innovative contributions to a variety of experimental analyses that may lead to contributions to scientific publications. Eventually, the candidate will implement end-user needs for everyone in the laboratory to be able to use the algorithms in the pipeline for large scale studies. Organization Campus Req Number 62932BR Job Title Bioinformatics Programmer Employee Class Career Percentage 100% Shift Length 8 Hours Shift Days Additional Shift Details Monday - Friday, 40 hours per week Bargaining Unit 99 - Policy-Covered (No Bargaining Unit) Job Category Clinical Systems / IT Professionals Required Qualifications • Bachelor's degree in biological science, computational / programming, or related area • Minimum 3+ years of related experience and/or training. • Thorough knowledge of bioinformatics methods, applications programming, web development and data structures. • Thorough knowledge of bioinformatics programming design, modification and implementation. • Thorough skills associated with statistical analysis and systems programming • Experienced with Unix • Knowledge of relevant biology • Ability to produce high-quality reports and documentation Preferred Qualifications • Master's degree in biological science, computational/programming • Advanced degree in Information Technology or related discipline • Understanding of relational databases, web interfaces, and operating systems. • Strong project management skills. • Thorough knowledge of modern biology and applicable field of research. • Communication skills to work with both technical and non-technical personnel in multiple fields of expertise and at various levels in the organization. • Ability to communicate technical information in a clear and concise manner. • Ability to interface with management on a regular basis. • Self-motivated, work independently or as part of a team, able to learn quickly, meet deadlines and demonstrate problem solving skills. • Thorough knowledge of web, application and data security concepts and methods. • Experienced with open-source development (e.g., maintenance, contributions) • Experienced with compute clusters and job schedulers • Experienced with version control (e.g., Git) and corresponding repositories (e.g., GitHub) • Experience with cloud computing • Skills to communicate complex information in a clear and concise manner both verbally and in writing. • Skilled in Tableau or other data visualization tools, SQL tables, queries and stored procedures, Python or other programming language(s), Familiarity with ETL processes, VBA in MS Excel or MS Access, charting/visualizations using MS Excel. • Demonstrated ability to communicate technical information to technical and non-technical personnel at various levels in the organization • Demonstrated ability to work with others from diverse backgrounds. Demonstrated effective communication and interpersonal skills. Demonstrated service orientation skills • Demonstrated strong problem-solving skills. Able to learn effectively and meet deadlines • Critical thinking skills and attention to detail Position Type Full Time Department Name Helen Diller Family Comprehensive Cancer Center Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Department Description The UCSF Cancer Immunotherapy Program (CIP) at the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC) comprising of the Cancer Immunotherapy Clinic and the Cancer Immunotherapy Lab on the Parnassus Campus, brings together expert UCSF physicians from across all cancer sub-specialties, to work closely with scientists from UCSF and beyond to develop the cancer treatments of the future. About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values. In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu Join us to find a rewarding career contributing to improving healthcare worldwide. Location Mission Bay (SF

Twist is looking for a Bioinformatics Scientist to join our Production Bioinformatics Team. You will work alongside research scientists, software engineers and data scientists to further deliver on our mission to expand access to best-in-class synthetic biology and next-generation sequencing applications. You will be developing and engineering tools to better evaluate and build hardened... production quality pipelines, optimize data quality, and automate lab and bioinformatics processes. Our ideal candidate is an organized problem solver with a background in developing and building novel production-quality bioinformatics tools and packages. Equally excellent communication skills and a proven ability to work independently are required. Responsibilities • Collaborate with R&D and Field Application Scientists to develop, build, and validate bioinformatics tools starting from proof-of-concept to production-grade software. • Apply scientific and engineering best practices to update and transition bioinformatics algorithms and pipelines from Research to Production • Work closely with synthetic biology groups to develop and implement novel design algorithms and QC methods and tools • Maintain production bioinformatics tools and workflows through their lifecycle Required Skills And Experience • PhD or equivalent in Bioinformatics, Computer Science, Engineering, or another science with minimum of 2 years of industry experience • Proven ability to conceptualize, develop, and validate novel NGS design and QC methods based on established bioinformatics algorithms (eg. alignment, variant calling, de novo assembly, etc) and tools (eg. bwa, GATK, Picard, SPAdes etc) • Strong proficiency with Python, SQL, Bash, and Git with experience building packages with tests as well as strong written and verbal English communication skills • Experience with working in industry Production environment including validation and documentation • Able to effectively communicate and work remotely with teams using Slack, JIRA and Confluence • Ability to troubleshoot complex issues quickly and effectively Preferred • Excellent understanding of molecular biology, with an emphasis on DNA chemistry • Experience with synthetic biology design and/or QC • Experience working with Illumina sequencers, chemistry, and software • Experience with AWS, Docker, Airflow and Kubernetes • Experience with data science tools (Pandas, Spark) • Experience with Rust nice to have About Twist Bioscience Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA. At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers. Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making genetic testing affordable and accessible for everyone to guide health decisions across all stages of life. Our development... team works on a variety of projects ranging from innovations in healthcare systems to taming the chaos of biology. We are constantly improving our tools and technologies to deliver the highest quality actionable information to doctors and patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers. What you’ll do: • Architect and implement high throughput genomics pipelines using modern technologies, optimizing for robustness, scale, and for being deployed at labs around the world • Maintain, improve, and create new pipelines to support our ever-expanding catalog of production bioinformatics pipelines • Implement and evangelize software engineering best practices • Collaborate closely with bioinformaticians, molecular biologists, dev ops and software engineers What you bring: • Experience in analysis pipeline development, with a preference for high throughput genomics workflows (especially Illumina and PacBio sequencing and arrays) • Experience in contributing to large, shared software repositories. Python knowledge required • Passion about writing clean, reusable, and composable pipelines • Experience with High-Performance Computing (HPC) environments (e.g. S/UGE, LSF, and/or Amazon AWS) • Experience with Distributed Workflow managers, e.g.NextFlow, airflow, luigi, • Capability to lead technical efforts and create clarity around ambiguous requirements • Excellent communication (written and verbal) and data presentation skills • Preferred: Experience using and designing RESTful and RPC-style interfaces • Preferred: Experience with Docker or other containerization/virtualization • Preferred: Experience with CI/CD At Invitae, you’ll work alongside some of the world’s experts in genetics and healthcare at the forefront of genetic medicine. Our teams thrive in our dynamic organization, which has been designed to empower them to make the biggest impact they can for our patients. We give our employees the ability to explore interests and capabilities broadly within the organization. We prize freedom with accountability and offer significant flexibility. We also provide excellent benefits and competitive compensation in a fast-growing organization. At Invitae, we’re changing healthcare to change lives. Join us. At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. #LI-Remote #LI-JM1

The Position Bioinformatics Cloud Software Engineer... Genentech seeks a talented and highly motivated Software Engineer to develop a cloud based genomic analysis system in support of our Translational Genomics efforts. Our Translational Genomics efforts span the interface of human genetics, functional genomics, molecular biology, disease model engineering, tissue and cellular profiling, and advanced computational methodology. The primary focus of this position is to extend our existing orchestration system for large scale genomic analysis workflows into the cloud to enable Genentech researchers to scale the throughput of their genomic and genetic analyses as needed. Solutions will need to integrate cloud native concepts with microservice based components in an existing software ecosystem. A successful candidate will collaborate with interdisciplinary teams of Software Engineers, DevOps engineers and Computational Biology Scientists to design and implement cloud native software solutions with an emphasis on service-oriented architecture and containerized workflows. The work includes requirements gathering, design and architecture, as well as backend and frontend development. The candidate will use best practices of continuous integration and software delivery to accommodate the fast pace of innovation in Genentech Research. Successful candidates will meet many of the following requirements • You have a Masters degree or equivalent in Software Engineering, Computer Science, Bioinformatics, or similar and 6-10 years of relevant experience in an academic or commercial setting. • You have successfully planned and implemented multiple software projects throughout the whole development cycle (planning, implementation, testing, release, maintenance) following modern software development practices. • You are a full-stack software developer (backend+frontend) that if needed maintains its own dev-ops tool chain, but plays well with enterprise level solutions. • You are able to break down large problems into smaller microservice based components and can develop them independently or as part of a large team. • You have experience with cloud related concepts such as deployment via Kubernetes or AWS cloud formation, Monitoring and containerization. • Experiences and expertise with cloud related concepts such as building infrastructure using Terraform, AWS Cloud Formation, AWS Batch, Lambda and Code Pipeline is a must - an AWS certification on an associate level is a plus. • You have architected distributed systems with infrastructure automation, monitoring and alerting and you are familiar with troubleshooting distributed systems. • You have a focus on high-quality code, including automated testing and coding best practices and you are able to prepare and conduct code reviews. • You have experience with relational and non-relational DB technologies. Knowledge of other search, messaging and queuing technologies such as ElasticSearch, SOLR, RabbitMQ and Kafka are desirable. • You are a quick learner and your analytical skills help you to effectively translate technical and scientific process requirements into a software product. • You have strong experience in the use of a high-level, object oriented programming language such as Python, Go or Java and a strong understanding of Linux/Unix. • You are comfortable working both independently and collaboratively, and with handling several concurrent, fast-paced projects. • You are able to execute technical projects at global scale, across multiple teams and time zones. Strategic, analytical mindset and ability to innovate using technology to advance business goals. • Experience in managing data according to FAIR principles as well as tracking data lineage, ensuring data quality and improving data discovery is a plus. • You have strong communication skills and can untangle and discuss complex technical tasks. • Prior experience in a life science or drug development environment are beneficial. What to expect from us • A highly collaborative and dynamic research environment where we aim to advance the rate of scientific discovery using purposefully built solutions. • Access to large data sets, samples and compute resources. • Access to state-of-the-art technologies and pioneering research. • Participation in seminar series featuring academic and industry scientists. • Campus-like lifestyle with a healthy work-life balance. • Mentored opportunities to further develop professional skills. Who we are A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. We are a research-driven biotechnology company, whose medical innovations for cancer and other serious illnesses make a difference for patients across the globe. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page

About Ancestry: When you join Ancestry, you join a human-centered company where every person’s story is important. We believe that by discovering the struggles and triumphs of our past, we can foster deeper bonds and more meaningful connections among families and communities. Our talented team of scientists, engineers, genealogists, historians, and storytellers is dedicated to empowering... customers around the world from all backgrounds on their journeys of personal discovery. With more than 30+ billion digitized global historical records, 100+ million family trees, and 20+ million people in our growing AncestryDNA database, Ancestry helps customers discover their family story and gain a new level of understanding about their lives. Passionate about dedicating your work to enriching people’s lives? You belong at Ancestry. AncestryDNA is looking for an experienced bioinformatician who has deep AWS domain expertise and is an experienced infrastructure DevOps Engineer to lead our R&D Bioinformatics team and efforts. You will contribute as part of our DNA Science team, which includes data scientists, computational biologists, and population geneticists working at the forefront of combining our 20+ million sample genomics dataset with our vast collection of family history records and trees to empower the development of new methods and the creation of new insights into the histories of the human family. You will be reporting to the Director, Research and Bioinformatics. What You Will Do: • You will lead the DNA Science bioinformatics team with 2 direct reports • You will work independently and with other Engineering teams to develop tools on AWS for research • You will support the DNA Science research team by coordinating access to multiple datasets, ensuring the highest standards of privacy and security • You will be part of the team responsible for developing and operating the cloud environment that supports the research team. • You will collaborate across the organization to identify opportunities to change, improve the customer experience, and achieve departmental goals • You will be an organizational expert on AWS best practices and support learning and development of the DNA Science and DNA Engineering team Who You Are: • You will have a Masters in computer science, bioinformatics, or a related field. • Minimum 5 years of post-education experience working with cloud-based research infrastructure. • Knowledge of core Cloud Computing concepts and advanced-level experience with AWS is required. • Advanced knowledge of Linux (including system administration) and Python programming. • Experience managing teams. • Experience with CI/CD (e.g. Jenkins), IAC (e.g. Terraform), Workflow-based distributed scientific analysis pipelines (e.g. Snakemake), network file system (e.g. Gluster), and job managers (e.g. Slurm) • Knowledge of storage performance concepts (iops, throughput, and performance bottlenecks) • Experience working with distributed computing tools (Hadoop, Hive, Spark) Additional Information: Ancestry is an Equal Opportunity Employer that makes employment decisions without regard to race, color, religious creed, national origin, ancestry, sex, pregnancy, sexual orientation, gender, gender identity, gender expression, age, mental or physical disability, medical condition, military or veteran status, citizenship, marital status, genetic information, or any other characteristic protected by applicable law. In addition, Ancestry will provide reasonable accommodations for qualified individuals with disabilities. All job offers are contingent on a background check screen that complies with applicable law. For San Francisco office candidates, pursuant to the San Francisco Fair Chance Ordinance, Ancestry will consider for employment qualified applicants with arrest and conviction records. Ancestry is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at Ancestry via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Ancestry. No fee will be paid in the event the candidate is hired by Ancestry as a result of the referral or through other means

The Position At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity. We believe every employee makes a difference. We are passionate about transforming patients’ lives. We are courageous in both decision and... action, we believe that good business means a better world. This position is part of the Individualized Medicines Team in Pharma Cell and Gene Therapy Group (PTC) responsible for the process development, manufacture and supply of personalized immunotherapies in collaboration with our global partners. We are seeking a highly motivated team member to contribute to the ongoing effort to evaluate and operationalize NGS and bioinformatics aspects of individualized medicine manufacturing. You will conduct bioinformatics analysis to support ongoing process development, refinement of the analysis pipelines and clinical manufacturing operations. The successful candidate is expected to effectively communicate and develop collaborative relationships with key stakeholders. Once a strategic framework for future manufacturing is in place, you will play a critical role in process development/implementation to enable commercial manufacturing of next generation therapeutics. Responsibilities • You will provide bioinformatics support to ongoing NGS process and assay development activities for individualized therapies. • You will collaborate with internal and external stakeholders to develop process understanding of existing pipelines and algorithms. • You will provide computational/bioinformatics support as needed across the broader PTC community. • You will author technical and validation reports for bioinformatics and assay development activities. • You will provide strategic and operational support needed for bioinformatics functions within Genentech’s individualized medicines program and broader PTC. • You will play a critical role in enabling a new manufacturing paradigm for Roche/Genentech that includes next-generation sequencing and advanced bioinformatics techniques to deliver individualized immunotherapeutics to patients. Qualifications The ideal candidate will meet the following qualifications: • Ph.D or MS in bioinformatics or a related discipline. 3+ years industry experience in bioinformatics analysis. • Expertise coding in Python, R or Matlab and using version control (git, svn) • Previous experience using and developing bioinformatics pipelines for NGS data analysis (WES, WGS, RNAseq, scRNASeq, amplicon seq etc), including profiling accuracy of tools/algorithms. • Experience authoring technical documentation, in collaboration with diverse stakeholders. • Previous experience building pipelines/algorithms supporting NGS assay development is a plus. • Experience working with third generation sequencing data (Nanopore, Pacbio) is a plus. • Prior experience in bioinformatics aspects of cancer immunology is a plus. • Must be detail-oriented with excellent collaborative and organizational skills in order to manage multiple projects and meet assigned deliverables. • Strong written and verbal communication skills and ability to effectively communicate with cross-functional teams. • Strategic agility and ability to adapt to the evolving personalized healthcare environment. • Comfortable working in a flexible, fast-paced team environment #ptcareers

About Mission Bio Mission Bio is a high-growth, well-funded Series C company based in South San Francisco, California. Our mission is to enable our customers to eradicate cancer. We do so with our innovative microfluidic system that is the leader in the high throughput single cell, multi-omics space that is used by major cancer centers and pharma / biopharma companies globally to better... characterize cancer as well as providing solutions to accelerate therapeutic development, such as the future standard of care in cell and gene therapy. We are a dynamic and diverse team. We live by the culture of “One Cell One Team One Vision”. We are collaborative, we are driven, and we are curious. Field Bioinformatics Specialist - US The Field Bioinformatics Specialist (FBS), preferably based in the larger San Francisco Bay Area will provide support by assisting scientists and researchers to analyze data sets. The job goes beyond typical database programming, as you must demonstrate experience and capability in chemistry, biology, or other life sciences. As a key member of the Team, you will also assist in the development and improvement of key commercial processes to ensure that Mission Bio provides customers with world class support. The position is a multifunctional leadership role that will help in driving Mission Bio’s efforts into research, biopharma, and clinical segments. The position will be responsible for the development, maintenance and provision of bioinformatics and applications support and training on Mission Bio’s product portfolio, thereby contributing to rapid platform/application adoption and customer satisfaction. The ideal candidate will have molecular biology experience and has worked as part of a multi-disciplinary team encompassing the whole experimental cycle from sample collection to analysis. Previous industry experience in the role is desired. Duties and Responsibilities: • Provide high quality, effective informatics support to customers and prospective customers in territories through knowledge of Mission Bio’s products (expertise around variant calling and single-cell research preferred) and effective communication of applications related to these products. • Communicate research results through conference presentations, scientific publications, or project reports. • Coding experience in Python • Familiar with Linux based operating systems • Consult with researchers to analyze problems, recommend technology-based solutions, or determine computational strategies. • Advise others on the development or use of new technologies. • Analyze large molecular datasets such as genomic sequence data, and proteomics data for clinical or basic research purposes. • Keep abreast of new biochemistries, instrumentation, or software by reading scientific literature and attending professional conferences. • Confer with departments such as marketing, business development, and operations to coordinate product development or improvement. • Collaborate with software developers in the development and modification of commercial bioinformatics software. • Participate in the organization and running of meetings, seminars, and training courses. • Actively participate in the development and support of strong relationships with customers collaborating with the Field Application Scientists. • Establish and maintain strong, positive, productive relationships with customer accounts. • Be a liaison in conjunction with Support Leadership and Sales to Marketing, R&D, and Bioinformatics departments pertaining to the current needs of the defined market segments identified through VOC experience. • Coach, mentor and develop incoming team members within the Support and Application departments including overseeing new employee onboarding. • Be a leader within the Support/Sales organization by proactively and independently addressing customer and product/applications concerns via active participation in routine cross-functional team communications. • Some travel may be required (up to 30%). Required Skills: • Previous experience giving oral presentations, teaching, or training other scientists. • Proven ability of effective written and verbal communication and listening skills. • Strong interpersonal skills and the ability to effectively communicate and project both during face to face and telephone interactions. • Strong proven commitment to customer service and satisfaction, the ability to effectively work on and manage many priorities at one time with excellent troubleshooting, writing, and editing skills. • Demonstrated success working in a fast-paced, dynamic environment. • Ability to work independently and as part of a team towards corporate goals. • Based in the United States, preferably in the larger San Francisco Bay Area. Education and Experience: • Bachelor’s in Molecular Biology with 3 years of related field or a related field required, MS or PhD strongly preferred. • You should have a minimum of three years of lab or relevant experience with proven knowledge and understanding of molecular biology (NGS), cancer biology/oncology, informatics, and related fields. • Bioinformatics experience with an NGS company or relevant industry is desired but not essential. Employee Perks: • Comprehensive Benefits: We offer medical, dental and vision insurance, pre-tax commuter options and a 401(k) plan for all US employees. • Flexible working hours: We offer unlimited vacation for you to take the time you need to recharge and be your most productive self at work. • Training and professional development: Your manager will work with you to define objectives for your professional development and help you progress in your field. Mission Bio is an equal opportunity employer. We welcome and encourage diversity in the workplace regardless of race, gender, sexual orientation, gender identity, disability or veteran status or any other characteristic protected by federal, state or local laws. Mission Bio is an equal opportunity employer. We welcome and encourage diversity in the workplace regardless of race, gender, sexual orientation, gender identity, disability or veteran status or any other characteristic protected by federal, state or local laws