Bioinformatics Jobs

Details Open Date 10/01/2024 Requisition Number PRN39994B Job Title Bioinformatics Data Analyst I Working Title Bioinformatics Data Analyst I Job Grade F FLSA Code Administrative Patient Sensitive Job Code? No Standard Hours per Week 40 Full Time or Part Time? Full Time Shift Day Work Schedule Summary VP Area President Department 02347 - HCI Birgit Knoechel Resch Prog Location Campus City Salt Lake City, UT Type of Recruitment External Posting Pay Rate Range 47600 to 61384 Close Date Open Until Filled Yes Job Summary The Bioinformatics Core Facility at the University of Utah, jointly managed by the University of Utah Health Science Center and the Huntsman Cancer Institute, seeks a Bioinformatics Data Analyst to join its staff. This individual will assist researchers with the design of next-generation sequencing and microarray experiments, analyze and interpret data from those experiments, and evaluate or create new data analysis and data management tools. Huntsman Cancer Institute is committed to cancer prevention, care, and survivorship for all communities within the area we serve – which includes Idaho, Montana, Nevada, Utah, and Wyoming – with impact worldwide. In your cover letter or during your interview process, we invite you to share how your professional experiences have prepared you to serve as a member of our team as we work to reduce the cancer burden experienced by all people and communities. This may include description of your prior experiences related to research, prevention, clinical care, community engagement/outreach, training, administration, or other areas relevant to Huntsman Cancer Institute’s mission and this position. Responsibilities Essential Functions: • Analysis of data from high throughput sequencing and microarray experiments. • Create, maintain, and document computer software for data analysis and management. • Assist researchers with the design of genomic experiments. • Instruct personnel in collaborating labs in the use of analysis methods and tools. This job description is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job. Work Environment and Level of Frequency typically required Nearly Continuously: Office environment. Physical Requirements and Level of Frequency that may be required Nearly Continuously: Sitting, hearing, listening, talking. Often: Repetitive hand motion (such as typing), walking. Seldom: Bending, reaching overhead. Minimum Qualifications Bachelor’s of Science degree with a focus on Bioinformatics, Biostatistics, Computer Science or Molecular Biology or equivalency (one year of education can be substituted for two years of related work experience). Two years of experience in genomic data analysis required. Demonstrated human relations and effective communication skills also required. Software development experience in object oriented programming using Java, Python, and or C++ and familiarity with molecular biology, genomics and some biostatistics helpful. Master of Science degree or PhD in Bioinformatics, Computer Science and/or Life Sciences preferred. Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description. Preferences Type Benefited Staff Special Instructions Summary Additional Information The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service, may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules. This position may require the successful completion of a criminal background check and/or drug screen. The University of Utah values candidates who have experience working in settings with students and patients from all backgrounds and possess a strong commitment to improving access to higher education and quality healthcare for historically underrepresented students and patients. All qualified individuals are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law. Upon request, reasonable accommodations in the application process will be provided to individuals with disabilities. The University of Utah is an Affirmative Action/Equal Opportunity employer and does not discriminate based upon race, ethnicity, color, religion, national origin, age, disability, sex, sexual orientation, gender, gender identity, gender expression, pregnancy, pregnancy-related conditions, genetic information, or protected veteran’s status. The University does not discriminate on the basis of sex in the education program or activity that it operates, as required by Title IX and 34 CFR part 106. The requirement not to discriminate in education programs or activities extends to admission and employment. Inquiries about the application of Title IX and its regulations may be referred to the Title IX Coordinator, to the Department of Education, Office for Civil Rights, or both. To request a reasonable accommodation for a disability or if you or someone you know has experienced discrimination or sexual misconduct including sexual harassment, you may contact the Director/Title IX Coordinator in the Office of Equal Opportunity and Affirmative Action ( OEO /AA). More information, including the Director/Title IX Coordinator’s office address, electronic mail address, and telephone number can be located at: https://www.utah.edu/nondiscrimination/ Online reports may be submitted at oeo.utah.edu https://safety.utah.edu/safetyreport This report includes statistics about criminal offenses, hate crimes, arrests and referrals for disciplinary action, and Violence Against Women Act offenses. They also provide information about safety and security-related services offered by the University of Utah. A paper copy can be obtained by request at the Department of Public Safety located at 1658 East 500 South.

Why choose between doing meaningful work and having a fulfilling life? At MITRE, you can have both. That's because MITRE people are committed to tackling our nation's toughest challenges—and we're committed to the long-term well-being of our employees. MITRE is different from most technology companies. We are a not-for-profit corporation chartered to work for the public interest, with no commercial conflicts to influence what we do. The R&D centers we operate for the government create lasting impact in fields as diverse as cybersecurity, healthcare, aviation, defense, and enterprise transformation. We're making a difference every day—working for a safer, healthier, and more secure nation and world. Our workplace reflects our values. We offer competitive benefits, exceptional professional development opportunities, and a culture of innovation that embraces diversity, inclusion, flexibility, collaboration, and career growth. If this sounds like the choice you want to make, then choose MITRE—and make a difference with us. Department Summary: The Biotechnology and Life Sciences Department within the Emerging Technologies Innovation Center is looking for a Group Leader for the Bioinformatics & Data Analytics group. The Group Leader will be part of a Department Leadership Team and will provide direct supervision of and mentorship to a diverse team working across MITRE’s biotechnology sponsor base on bioinformatics, computational biology, data analytics, and synthetic biology problems. This role can be performed from McLean, VA, Bedford, MA, or remotely. This role can be performed from McLean, VA, Bedford, MA, or remotely. Roles & Responsibilities: In addition to being a strong technical contributor, the Group Leader will serve as the primary point of contact on human resource matters for assigned staff and be responsible for staff engagement, coaching, collaboration, and professional development. Major aspects of this role will be to provide strategic vision, ensure the professional development of staff, and grow/develop an impactful work programs related to computational biology, data analytics, AI/Bio, and synthetic biology. As first-line supervisor, the Group Leader: • Maintains awareness of USG efforts with a heavy bioinformatics, data analytics, or synthetic biology component, identifies opportunities for MITRE impact, and engages across MITRE and with sponsors to develop and grow impactful work. • Develops and executes a holistic vision for the group that supports the department strategic plan • Engages with leaders in MITRE AI and data analysis efforts and maintains awareness of relevant internal efforts, initiatives, and programs • Works with the department Chief Engineer to ensure staff members technical skills are being maintained and expanded • Works with staff to establish appropriate roles with well-defined goals, ensuring performance feedback is received and understood and helps staff in navigating transitions between projects. • Works with other Group Leaders and department leadership to create a vibrant inter-group dynamic in which collaboration, mentoring and development across groups is nurtured and encouraged. • Coach, mentor, and support staff who have broad technical expertise spanning biomedicine, biodefense, computational modeling, and biomechanics to maximize their short- and long-term career success • Coordinate with organizations across MITRE to connect employees with projects, individuals, MITRE communities, and training resources aligned with the employee’s career aspirations. • Engage in ongoing and meaningful development-focused and career conversations on topics including work assignments, role expectations, learning opportunities, delivering value (e.g., the Mission Value Chain), performance, feedback, and professional development. • Provide guidance to staff on expectations for performance and department goals and objectives with which staff can identify; effectively recognizes and rewards both individual and team achievements in accordance with MITRE values • Work with other Group Leads of other areas to identify, shape, and staff computational work in c-WMD, Medical Countermeasures, Injury Prevention, and Biological Safety and Quality The successful candidate will be a motivated technical leader and experienced mentor who has the experience, skills, and confidence required to take on this role. A Group Leader is expected to balance management duties with direct work program contributions. Key Functions of the GL role include: • Individual Contributor/Task Leader – Functions as a SME across Department relevant domains. Provides technical leadership to core Department work programs. • Staff Engagement – Serves as the direct supervisor for 7-10 assigned staff, providing technical support, conducting regular performance and development conversations, staff advocacy and recognition, and communication with Project/Task Leads on performance. Serves as the main point of contact for new employee onboarding and as a resource to guide staff in navigating the MITRE organization and processes • Recruiting and Hiring – Plays a key role in the department recruiting and hiring process including identifying when additional staff are required and participation in candidate presentations and technical panel interviews. • Collaboration and Communications – Supports regular communication between staff and Project/Task Leaders and serves as a proactive liaison between staff and Department/upper management Basic Qualifications: • Bachelor’s Degree in one of the following disciplines: computational biology, bioinformatics, data analytics, qualitative research, synthetic biology, or related field and 8 years related experience. • Ability to obtain and maintain a US Secret security clearance. • The candidate should possess the ability to define projects or programs greater than themselves. • Demonstrated expertise and proven track record in bioinformatics, computational biology, synthetic biology or a similar field • Excellent written and verbal communication skills • Ability to coach, mentor, and advocate for staff. Desire to help staff at various points in their careers • This position requires a minimum of 50% hybrid on-site Preferred Qualifications: • Master’s degree and 10 years of experience or Ph.D. and 5 years’ experience • At least one year of experience working in a MITRE Innovation Center • At least one year of experience as project or technical lead of a computational biology or synthetic biology related project • Management experience, either at the project or department level • Familiarity with L271 and/or the MITRE wide bioinformatics/analytics work program • Active clearance This requisition requires the candidate to have a minimum of the following clearance(s): Secret This requisition requires the hired candidate to have or obtain, within one year from the date of hire, the following clearance(s): Top Secret Work Location Type: Hybrid MITRE is proud to be an equal opportunity employer. MITRE recruits, employs, trains, compensates, and promotes regardless of age; ancestry; color; family medical or genetic information; gender identity and expression; marital, military, or veteran status; national and ethnic origin; physical or mental disability; political affiliation; pregnancy; race; religion; sex; sexual orientation; and any other protected characteristics. For further information please visit the Equal Employment Opportunity Commission website EEO is the Law Poster and Pay Transparency. MITRE intends to maintain a website that is fully accessible to all individuals. If you are unable to search or apply for jobs and would like to request a reasonable accommodation for any part of MITRE’s employment process, please email recruitinghelp@mitre.org. Copyright © 2024, The MITRE Corporation. All rights reserved. MITRE is a registered trademark of The MITRE Corporation. Material on this site may be copied and distributed with permission only. Benefits information may be found here

The department of Computational Biology is seeking an experienced lead or principal-level bioinformatics research scientist to provide direction and lead the development of pipelines for use in our clinical genomics program. The clinical genomics program at St. Jude Children’s Research Hospital started in 2013 as a pioneer in the use of whole genome sequencing for clinical testing. This position in the department of Computational Biology will play a key role in continuing our innovation in this space. The ideal candidate brings knowledge of cancer biology and stays abreast of current methods and trends in published literature. By leveraging this knowledge, working in productive collaboration with stakeholders, this role can proactively identify viable opportunities and effective solutions, thereby serving as a catalyst to innovation within the clinical genomics program. This role involves directing the efforts of the multidisciplinary team that performs end-to-end development of bioinformatics pipelines, including evaluation of existing methods, development of annotation and filtering strategies, and validation in accordance with CAP/CLIA requirements. This requires bioinformatics rigor applied in a clinical context where turnaround time limits, workflow considerations, and unique analytical performance criteria apply. Candidates must possess strong communication and interpersonal skills, as the position will engage regularly with pathologists, analysts, bioinformaticians, and engineers within the departments of Pathology and Computational Biology, as well as clinicians and scientists from various departments in the institution. Job Responsibilities: • Design and lead advanced analyses and deliver high-quality results in a timely manner by identifying new technologies and methodologies and recommend for adoption when appropriate. • Coordinate development of novel software tools and infrastructure as scientific and technical advisor, by contributing code and providing scientific guidance to developers. • Conceptualize, initiate, and lead manuscript preparation and submission of benchmarking results, new pipelines, databases, and scientific discoveries where appropriate. • Establish best practices and new protocols for analysis matching skills and expertise, and share protocols with St. Jude investigators through open documentation and hands-on training. • Assist in acquiring funding to support methods evaluation, development, and infrastructure. • Lead and coordinate the development of curriculum to educate the St. Jude community. • Is an independent project leader for large-scale projects and mentors junior staff. • Perform other duties as assigned to meet the goals and objectives of the department and institution. • Maintains regular and predictable attendance. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Lead/Principal Bioinformatics Research Scientist, Clinical Genomics. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160 countries. ABOUT ABBOTT DIAGNOSTICS The key to successful treatment and full recovery is often fast, accurate diagnosis. Abbott’s life-changing tests and diagnostic tools provide insights that enable smarter, faster decisions and transform the way the world is managing health. Our pioneering technology spans the world of healthcare operations — with medical diagnostic instruments, tests, automation and informatics solutions for hospitals, reference labs, blood centers, emergency departments, physician offices and clinics. Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: • Career development with an international company where you can grow the career you dream of. • Free medical coverage for employees* via the Health Investment Plan (HIP) PPO • An excellent retirement savings plan with high employer contribution • Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. • A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune. • A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Opportunity Our Diagnostics business currently has an opportunity for the role of Senior Bioinformatics Scientist II for our Abbott Park (Waukegan, Illinois) location. The primary function of this position is to manage biologic sequence data as well as collect, generate, and manage descriptive and analytic data related to such bioinformatics data. The Bioinformatics Scientist enables colleagues to access bioinformatics data and continuously improves the quality and accessibility of bioinformatics data. What You’ll Work On • Responsible for implementing and maintaining the effectiveness of the quality system. • Designs and conducts experiments, accomplishes established milestones, organizes and summarizes data, interprets and reports results, draws conclusions. Evaluates data using analytical methodologies to achieve results. Recommends options for future analyses. Presents scientific observations to others. • Expertise and Problem Solving: Leverages experience in biology, computer science, modeling, statistics, analytics and math to derive insights from large biological sequence data sets. Maintains knowledge of sequencing technologies and their applications. Identifies technical alternatives. Anticipates, recognizes and resolves technical problems. • Project Planning: Participates in project planning, updates and process improvements. Implements project plans comprehending resource, budget, facility and regulatory requirements. Translates top-level goals to specific project level goals for the individual team member. Establishes and reviews complex plans for multiple projects or activities. Liaise with Global Information Technology, Asset Management, and Software Quality on behalf of project stakeholders. Plans resource allocation and distribution. • Scientific Leadership: Submits ideas for inventions or publications and participates in application and report generation. • Economic Profitability: Provide direction to project team to meet economic profitability (EP) profile for the project (product cost analysis). • Documentation: Appropriately documents experimental procedures and results according to established guidelines. • Position addresses problems of systems integration, compatibility, and multiple platforms. • Translates business needs into technical systems solutions. EDUCATION AND EXPERIENCE YOU’LL BRING Qualifications: • Associates Degree or higher required; Bachelors Degree with strong focus on Computer Science field preferred. • Minimum 4 years experience. Preferred Qualifications • Masters Degree. • SQL database and BASH (shell) experience preferred. • Cloud computing experience preferred. Learn more about our benefits that add real value to your life to help you live fully: http://www.abbottbenefits.com/pages/candidate.aspx. Follow your career aspirations to Abbott for diverse opportunities with a company that provides growth and strength to build your future. Abbott is an Equal Opportunity Employer, committed to employee diversity. Connect with us at www.abbott.com, on Facebook at www.facebook.com/Abbott, and Twitter @AbbottNews and @AbbottGlobal. ok.com/Abbott and on Twitter @AbbottNews and @AbbottGlobal. The base pay for this position is $83,000.00 – $166,000.00. In specific locations, the pay range may vary from the range posted.

Help us change lives At Exact Sciences, we're helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others. Position Overview The Bioinformatics Scientist I, with limited guidance from more experienced scientists, works individually and in collaboration with others on multiple projects which are moderate to complex in scope. The Bioinformatics Scientist I plays an active role in planning of projects and analyses and is often the bioinformatics lead responsible for the successful execution of the project. This position involves independently making detailed observations, analyzing data and interpreting results. Working in a team setting, the Bioinformatics Scientist I, will primarily be involved in Research and Development projects serving as a technical lead in translating research ideas and concepts into the product development pipeline towards development of diagnostic assay products. Essential Duties Include, but are not limited to, the following: • Conduct analyses within several product or technology areas and identify problems and discrepancies. • Independently plan and analyze results of bench level experiments within several product or technology areas. • Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment. • Utilize and apply methods or technologies effectively and provide ideas for new techniques, when appropriate. • Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures. • Provide technical input and participate in decisions affecting project planning and experimental design. • Prepare and provide information and data for scientific abstracts/conferences/project meetings/publication. • Generate, document, and communicate development plans for critical aspects of a project. • Participate in the development of research plans and experimental outlines. • Prepare detailed technical procedures, protocols, and reports. • Evaluate impact of nonconforming data to product or process. • Identify and address trends in study data. • Prepare and approve written reports. • Lead identification of areas for process improvements. • Maintain lab notebook in a clear, complete, and consistent manner, following all legal, ISO, and QSR requirements. • Prepare reports and documentation providing the analysis or summarization of results, outcomes and next steps to supervisor, technical teams/groups, or project teams. • Present results and defend scientific ideas and findings at data meetings, group meetings, project team meetings, and/or departmental meetings; provide technical input as needed. • Demonstrate technical proficiency and knowledge, scientific creativity, collaboration with others, and independent thought and ability to provide insights and defend scientific ideas. • Work on problems of diverse and complex scope in which analysis of data requires evaluation of identifiable factors. • Exercise judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions. • Work on individual assignments and with project team members as appropriate to meet department and project objectives. • Work within project timeframes that are established collaboratively by team members. • Act as technical leader for one or more projects that are moderate to complex in scope. • Exercise discretion and independent judgement within broadly defined practices and policies in: selecting methods, techniques and evaluation criteria for obtaining and interpreting results; analyzing data and presenting findings in a professional and knowledgeable manner. • Promote an open, collaborative environment built on trust to foster positive teamwork. • Assist in planning and recommendation of activities that account for prioritization of organizational and department goals. • Ability to train and mentor bioinformatics associates. • Ability to organize, present, and convey moderate problems or issues. • Ability to communicate clearly with supervisor and group members. • Demonstrate excellent presentation. • Ability to collaborate, work effectively and contribute within team, department, and cross functional teams. • Demonstrate strong attention to detail skills. • Ability to effectively work on several varied projects at one time, with frequent changing priorities. • Demonstrate excellent analytical, problem solving and decision-making skills. • Apply sound technical knowledge and ability gained through experience and/or learning. • Apply previous knowledge and outcomes to new and valuable problems (able to make predictions based on a deep understanding of the fundamental nature of the inputs into a decision or action). • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork. • Support and comply with the company's Quality Management System policies and procedures. • Maintain regular and reliable attendance. • Ability to act with an inclusion mindset and model these behaviors for the organization. • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day. • Ability to work on a computer and phone simultaneously. • Ability to travel 5% of working time away from work location, may include overnight/weekend travel. Minimum Qualifications • PhD in bioinformatics, computational biology, computer science, mathematics, or related field; or Master's degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 4 years of experience in lieu of a PhD; or Bachelor's degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 6 years of experience in lieu of PhD. • 1+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry. • Extensive experience in Linux-based HPC or cloud computing environments and associated tools. • Ability to write custom code in at least three programming or scripting languages. • Knowledge of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics. • Working knowledge of statistical and mathematical methods in biology/genetics/genomics, including experience with statistical software, such as JMP or R. • Basic computer skills to include Internet navigation, Email usage, and word processing. • Proficient in Microsoft Office to include Excel, Word, and PowerPoint. • Demonstrated ability to perform the essential duties of the position with or without accommodation. • Authorization to work in the United States without sponsorship. Preferred Qualifications • 2+ years of industry or academic experience, post doc. • Experience in an FDA-regulated environment, ideally in medical device development. • Experience in a biotech manufacturing environment, preferably in an GMP and/or ISO environment. Salary Range: $93,000.00 - $149,000.00 The annual base salary shown is for this position located in US - CA - San Diego on a full-time basis. In addition, this position is bonus eligible, and is eligible to receive company stock upon hire as well as annually. Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits . Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here . Not ready to apply? Join our talent community and stay up to date on what's new at Exact Sciences. We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state, or federal law. Any applicant or employee may request to view applicable portions of the company's affirmative action program. To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub . 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This Position is Grant Funded School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. Bioinformatician I Summary We are looking for a talented and motivated individual to work with teams of Researchers and Scientists providing bioinformatics expertise, consulting, application development, and support as part of the Duke Predictive Modeling Center (PMC), an NHGRI-funded center with the Impact of Genomic Variation on Function (IGVF) Consortium. Work performed • Contribute to the design, development, adaptation, implementation, and testing of neural networks that are used for predictive modeling of genomic data. (30%) • Train predictive models using machine learning approaches and technologies. This might include not only writing new code but repackaging and documenting existing scripts to make them reusable and easy to maintain. Work will include training models and will require navigating dynamic computing environments. (25%) • Collaborate and consult with researchers individually or in small groups to analyze problems, recommend technology-based solutions, and design computational strategies for a wide range of biological research. Initiate interdisciplinary collaborations with other centers or departments within the Duke PMC and in collaboration with other research teams with the IGVF consortium. (20%) • Recommend new methods, strategies, and improvements to incorporate into existing models. Try latest tools and analysis methods for new non-conventional genomic data (e.g. CRISPR screens), evaluating their fit and gradually incorporating them into existing analysis pipelines. (15%) • Provide training on bioinformatics-related concepts, applications and tools to researchers across the PMC and relevant teams within the IGVF. Design and participate in hands-on workshops to teach scientists how to use predictive models and associated neural networks so that these resources are accessible to other groups. (10%) Skills • Experience working with high throughput sequencing datasets (e.g. RNA-seq, ChIP-seq, ATAC-seq, etc.). • Strong and demonstrable programming skills in Python, Tensorflow, and/or R. • Experience with collaborative development environments, including management of shared repositories (github). • Good communication skills; run and deliver results in a clear and precise way. • Familiarity with High Performance Computing clusters (e.g. SLURM, PBS), including computing environments constructed with CPUs and GPUs. • Familiarity with workflow languages (e.g. CWL, WDL). Education This position requires a B.S. in Bioinformatics or the Biological Sciences with demonstrable computational skills; or a B.S. in Computer Science with a strong interest in Biology/Genomics. M.S. preferred. Experience Strong expertise with programming required. Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

The Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Provides bioinformatics analysis for investigators and communicates analytical process and results. The Center for Applied Bioinformatics (CAB) at St. Jude Children's Research Hospital is seeking a highly motivated Senior Bioinformatics Research Scientist to join the Transcriptomics Group. CAB is an institutional shared resource dedicated to providing state-of-the-art bioinformatics services to St. Jude investigators. Our Center collaborates with lab scientists and physician-scientists at multiple stages of their research, from study design, data analysis to preparation for presentations, grant proposals, and co-authoring manuscripts. We uphold the highest level of scientific rigor by carefully vetting and documenting all bioinformatics methods and pipelines. The successful candidate will develop and apply innovative analytical approaches to analyze & interpret new and existing multi-omic datasets obtained from both clinical and basic research lab, including bulk tumor/normal, single-cell/nucleus, and spatial-omic profiles. These analyses will contribute to understanding the underlying mechanisms driving pediatric cancers and other human diseases. The candidate will work closely with other bioinformatics personnel within CAB, playing an integral role in exciting research partnerships both within St. Jude and with external collaborators. He/she will contribute to establish the pipelines and best practice to characterize bulk or single cell RNA isoforms and noncoding RNA transcripts with long read sequencing technologies. He/she follows and adheres to best practices in structured transparent project management by tracking progress, identifying roadblocks, and proposing solutions, developing specific milestones for each research goal, and providing informative progress reports and summaries to principal investigators. The Center provides a highly interactive environment with collaborative opportunities across basic and clinical departments. You'll have access to high performance computing clusters, cloud computing environments, innovative visualization tools, highly automated analytical pipelines, and mentorship from experienced scientists. Members of this Center have the opportunities to publish high profile papers with prominent authorship depending on their intellectual contributions. The ideal candidate should have: · A PhD and extensive post-PhD experience in bioinformatics, computational biology, and data science. · A strong CV that includes high-profile publications in the field of computational biology, cancer genomics, and/or single-cell genomics. · Experience analyzing some/all the following platforms: whole-genome/exome sequencing, RNA-seq. ATAC-seq, ChIP-seq/CUT&RUN, single-cell/nucleus RNA-seq, CITE-seq, single cell multiome (ATAC+GEX), spatial transcriptomics, and long-read sequencing (e.g., PacBio and Oxford Nanopore) · Proficiency in relevant programming languages such as R and Python, preferably in a High-Performance Computing (HPC) environment. · Proficiency in tools for ensuring reproducibility of pipelines, such as workflow management systems (e.g., nextflow), and version control (e.g., git). · Proficiency in tool development, including examples documented in public repositories. · Extensive expertise in data integration and harmonization. · Proven problem-solving skills and collaborative nature in fast-paced environment. · Excellent communication and presentation skills. Job Responsibilities: • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data. • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion. • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions. • Assist in the evaluation and testing of new methods and technologies. • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so. • Participate in the department's developmental projects and interdepartmental team projects. • Perform other duties as assigned to meet the goals and objectives of the department and institution. • Maintains regular and predictable attendance. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

WHY PATIENTS NEED YOU Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. POSITION SUMMARY Pfizer is seeking a talented, self-motivated Scientist (Bioinformatics) with background in developing analytical algorithm, data processing pipeline to support mRNA vaccine data analytics and next generation sequencing efforts in vaccines R&D team at Pearl River. Responsibilities will be driving therapeutic innovation through contributing to the vaccine development. You will apply analytical skills and develop bioinformatics tools used for whole genome sequencing, targeted sequencing, RNA sequencing and single cell sequencing. You will analyze sequence data and provide bioinformatics and data science support to various mRNA vaccines program. Work and documentation are to be done in a compliant manner according to relevant SOP guidelines and cGLP guidelines where appropriate. You will be part of a dynamic team and should possess a strong work ethic and collaborative spirit. POSITION RESPONSIBILITIES • Develop and manage automated next generation sequencing (NGS) pipelines to support pathogen or host genome sequencing projects • Implement various open source bioinformatic pipelines and interpret analytical results to support mRNA vaccines' preclinical and clinical programs • Experience and knowledge about bulk RNAseq, single cell RNAseq, TCR profiling, and BCR profiling • Develop novel algorithms and workflow for the analysis of vast amount data spanning different data types and provides scientific insights to guide vaccine design. • Present analytical results and review of literature at group meetings as needed. Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy. • Collaborate extensively with those from other scientific disciplines from within the group, from other subdivisions of Vaccines R&D, from other divisions of Pfizer MINIMUM QUALIFICATIONS • Degree in computer science, bioinformatics, data science, computational biology or related field is required. • Bachelor's degree with 8~10 years of experience or master's degree with additional 6-8 years of related experience is preferred. This is NOT a PhD position. • Extensive experience in analyzing multi-omics next generation sequencing data (e.g., genetics, bulk RNA-seq, single-cell RNA-seq, spatial omics, proteomics, etc.) for biomedical research. • Proficient coding/scripting in Python, R. Familiar with Biopython, Tidyverse, Bioconductor, scikit-learn • Familiar with Linux environments, high-performance computing and/or cloud computing environment and broad experience with open-source bioinformatics tools to generate scientific insight. • Must be comfortable with fast-paced environment handling multiple projects simultaneously with different priorities and timelines. Strong motivation, passion and commitment to interdisciplinary science and techniques. PREFERRED QUALIFICATIONS • Familiar with various sequencing platforms: Ion Torrent, Illumina, PacBio, Nanopore, 10x genomic • Familiar with public resources: GISAID, NCBI, EMBL, UniProt, PDB • Knowledge about vaccine development and immunology Job Location: On premise with relocation support available The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Research and Development

Job Title: Bioinformatics Scientist Location: Bethesda MD 20892 Duration: 3 Years to Long Term Shift: 40 Hour/Week (Mon to Fri) Teleworking Eligible: Yes Onsite: Yes This is at Federal Client Facility Overall Position Summary and Objectives • The contractor shall oversee the migration and harmonization of clinical data. • The role necessitates expertise in bioinformatics, data science, statistics, and database management to ensure the successful integration and analyses of clinical datasets. Min Education: • Master's Certifications & Licenses: • Ph.D. degree in a related discipline. • Three (3) years of specialized experience plus a Master's degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a BA/BS degree is equivalent to a Ph.D. Skills: • Strong computational, bioinformatics and statistics skills with a strong clinical interest, knowledge, and background. • Ability to learn how to use new software and quickly become expert in its use, critical thinking, problem-solving abilities, and the ability to work independently. Software: • Java • C, C++ • MS Office Suite Field of Study: • Neuroscience Statement of Work Details: • Provides programming and troubleshooting support to the Federal Government in the dissemination of research data. • Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects. • Performs computations on research data analysis. • Perform computational analysis of, and interpret results. • Works with staff on scientific programming and experimental design. • Work with staff on planning of experiments, and data analysis for internal and collaborative projects; use bioinformatics expertise to advise and help bench scientists on experimental design and trouble shooting. • Records observations and report results at weekly laboratory meetings. • Maintain proper and detailed documentation of the analysis performed and report results at lab meetings. • Provides statistical support / analysis on research data. • Perform data processing and data analysis with existing computational and statistical methods.

SHIFT: Day (United States of America) Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP’s Commitment to Diversity, Equity, and Inclusion CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. We strongly encourage all candidates of diverse backgrounds and lived experiences to apply. A Brief Overview The Bioinformatics Scientist III position is an intermediate level position for a PhD level professional and a final stage position for those with high experience without a PhD. The focus of the position is collaboration-level application of bioinformatics tools and methods to bench and clinical research problems in various biomedical domains. The position allows for a wide variety of activities described within the job responsibilities and encompasses positions within both research and clinical environments. Activities occur with a low degree of supervision with expectation for highly independent judgment, development of bioinformatics workflows and processes, and presentation of results. The Bioinformatics Scientist III will apply best practices in collaborative science as a bioinformatics domain scientific collaborator. Academic output is a focus of this position and is expected with a low degree of supervision. The Bioinformatics Scientist III is primarily focused on taking a lead, proactive scientific role in teams and projects as a bioinformatics domain expert. The Bioinformatics Scientist III must be able to perform all responsibilities listed in the Bioinformatics Scientist II job description. All responsibilities listed in this description are additional. What you will do • Pre-Analysis (10%): Actively participate in the development of application portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provide efficient data management support. • Lead development of additional pipeline functionality and changes by providing knowledge of both collaboration-specific requirements and bioinformatics discipline advances • Coding (10%): Code and generally support code and applications on behalf of collaborative project and/or team. • Master best practices for project-based code development, QC, and execution consist with the expectations of specific collaborations • Lead peer-to-peer code reviews by participating in informal and formal critical code reviews • Data Analysis (30%): Analyze data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data primarily under the direction of the collaborative project team • Lead regular peer-to-peer review of analysis plans in both informal and formal settings • Develop multiple specialty analytical areas that serve one or more collaborative teams • Lead adoption of best practices in specialty analytical or biomedical areas by the bioinformatics group and peers • Collaboration (30%): Lead bioinformatics portion of scientific collaborations as the primary bioinformatics resource • As bioinformatics point, assume management role for projects of low-to-moderate complexity, including all aspects of timelines, risk identification and mitigation strategies, and communication mechanisms • Directly manage all elements of project satisfaction and performance relative to scientific project aims • Promote continual objective, hard discussions about overall health of project and relationship • Develop new collaborations with moderate degree of supervision • Academic Output (20%): Lead project-based presentations, grant sections, and manuscript sections with subsequent review by peers and mentors • Regularly coordinate and write bioinformatics-focused manuscripts and publications • Regularly coordinate and lead podium presentations and posters • Proactively contribute to entire bioinformatics and other sections of grant and award proposals Education Qualifications • Master's Degree Required • Doctorate biological or computational discipline Preferred Experience Qualifications • At least five (5) years experience in applied bioinformatics, genomics, and computational work. This experience can be inclusive of a relevant PhD dissertation. Required Skills and Abilities • Ability to, under supervision, conceive of, plan, implement, validate, and disseminate entire research projects is required. • Ability to assume principal investigator or similar role in academic research is preferred. • Strong UNIX/LINUX expertise required. • Proficiency in R or similar commonly used bioinformatics language required • Experience with Python, Perl, or other languages required. • Experience with pipeline or workflow development frameworks preferred. • Experience with management and analysis of complex data types required. • Proficiency in various open source and commercial bioinformatics resources and software required. • Experience with genomic/proteomic data analysis methods required. • Experience or knowledge of technologies commonly used in biological labs, such as PCR, cloning, electrophoresis gels, and cell culture required. • Knowledge of the working mechanism of microarray, NGS, mass spectrometry, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is required. • Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is required. • Ability to correctly select and perform statistical tests for most types of genomic data, and to properly interpret their results in the scenario of a specific study is required. • Ability to leverage unique knowledge of bioinformatics, applied biostatistics, molecular biology, and measurement platforms for effective scientific discussion with biologists and clinicians is required. • Ability to determine most favorable academic output as a primary research outcome is preferred. • Ability to objectively critique results and present as valid or questionable, taking into account all aspects of study design, technical issues, and limitations of workflows is required. • Accountability and attention to timelines. • Excellent organization and communication skills with an emphasis on strong presentation skills • Ability to independently plan and execute analyses of moderate complexity required • Ability to provide objective validation of results required • Ability to work in a team environment. To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more. Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed. EEO / VEVRAA Federal Contractor | Tobacco Statement