Bioinformatics Jobs

Company This is a great opportunity for a Senior Bioinformatics Scientist to join a pioneering scale-up biotech company, that has developed their own unique Cloud Data platform which organizes and parses the deluge of new biology data, enabling to triangulate insights across genomics, epigenomics, transcriptomics, proteomics, and beyond... Role • Lead the development of new bioinformatics workflows, including, but not limited to: whole genome/exome sequencing, RNAseq (single-cell, bulk, spatial), ChIP-Seq, ATAC-seq (single-cell and bulk), proteomics, and metabolomics. • Collaborate with our full-stack engineering team on making these workflows efficient and performant. • Engage directly with customers (both biologists and Bioinformatician) on their deployment of the company's platform, ensure the technical success of client engagements, and communicate customer feedback and feature requests to the broader team. Requirements: • PhD in Bioinformatics, Computational Biology, Statistics Biology, or other relevant scientific field. • Experience analyzing gene editing sequencing data (GUIDE-seq, Circle-Seq, any kind of CRISPR/TALEN/ZNF off-target seq etc) • Ability to analyze integration pattern and rare events • Expertise in NGS (RNAseq/WGS/WES) • Experience with both Illumina and long (PacBio/Nanopore) reads a.ofosu@x4lifesciences.com Equal Opportunity Employer/Disability/Veterans

Overview Senior Bioinformatics Scientist... This position is eligible for a $3,500 Sign On Bonus for external candidates. Our team at The Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital is driven to create a future where no child with genetic disease goes undiagnosed and every child with cancer receives optimal treatment based upon their personal genome sequence. Recognizing that the root cause of many childhood diseases can be traced directly to the genome, our research program focuses on the development of novel technologies to analyze the billions of data points with a patient’s genome. We are looking for a Senior Bioinformatics Scientist to join the IGM Computational Genomics Group who shares our passion to advance the understanding of disease through the development of computational tools and the application of big data technologies. You will have the opportunity to work collaboratively within a dynamic team of bioinformaticians, data scientists, and software engineers developing novel computational and statistical approaches for the analysis and interpretation of genomic data. Why Nationwide Children's Hospital? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose. Here, Everyone Matters. We’re 14,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Cultureto deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud Responsibilities PRINCIPAL DUTIES AND RESPONSIBILITIES Our ideal candidate will have experience in computational approaches for genomic data analysis, including bioinformatics, data analytics and machine learning. You will primarily focus on the application of your skills to our research programs that study pediatric cancer, congenital heart defects and cardiovascular diseases, birth defects, and rare genetic diseases in collaboration with our research and clinical faculty. As a Senior Bioinformatics Scientist, you will have the opportunity to develop and drive independent computational genomics research projects, driven by your interests and skills. As we scale genome sequencing to thousands of patients, we are particularly interested in the application of artificial intelligence to the discovery and interpretation of genetic variation relevant to disease. This position is part of a distributed team that on occasion will need to come to the NCH main campus for meetings. The option for remote, hybrid or full-time on-site is available. Qualifications Education • PhD. in Bioinformatics or a related field with a focus on 'Omics'-based bioinformatics preferred • Minimum two years of postdoctoral experience or five years professional experience in computational biology or bioinformatics Responsibilities • Conduct research, development and evaluation of computational approaches to advance our understanding of pediatric disease • Perform next generation sequencing data analysis, interpretation and visualization • Based upon your experience and identifying an area you are passionate about, take a lead role in our translational research protocols or computational genomics research areas • Communicate findings to clinicians and researchers, author journal publications and present at professional meetings • Assist in supervision and training of junior bioinformatics scientists, analysts and trainees at the graduate and postdoctoral level Skills & Attributes • Fluency in programming and scripting languages is required (e.g., R, Python, etc.) and their use in LINUX and cloud computing environments • Expert knowledge of integrative -omics analysis, genomic data analysis (i.e. DNA-Seq, RNA-Seq, ChIP-Seq, etc), data mining, complex data analysis and statistics • Excellent interpersonal and communication skills and the ability to manage multiple projects while maintaining a high level of attention to detail Experience • Confident with the use of bioinformatics tools and databases, approaches to statistical analysis and data visualization methods • Strong understanding of molecular biology and genomics • Experience in algorithm development or machine learning approaches • Proven record of applying or developing computational biology approaches to generate and test new hypotheses • Must be a team player with a history of conducting collaborative and self-directed research within broader goals set by the group MINIMUM PHYSICAL REQUIREMENTS • Sitting – Frequently Talking on phone/in person – Frequently Typing on a keyboard – Constantly Standing/walking – Frequently Physically Active – Occasionally • The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. EOE M/F/Disability/Vet

Overview Senior Bioinformatics Scientist... This position is eligible for a $3,500 Sign On Bonus for external candidates. Our team at The Institute for Genomic Medicine (IGM) at Nationwide Children's Hospital is driven to create a future where no child with genetic disease goes undiagnosed and every child with cancer receives optimal treatment based upon their personal genome sequence. Recognizing that the root cause of many childhood diseases can be traced directly to the genome, our research program focuses on the development of novel technologies to analyze the billions of data points with a patient's genome. We are looking for a Senior Bioinformatics Scientist to join the IGM Computational Genomics Group who shares our passion to advance the understanding of disease through the development of computational tools and the application of big data technologies. You will have the opportunity to work collaboratively within a dynamic team of bioinformaticians, data scientists, and software engineers developing novel computational and statistical approaches for the analysis and interpretation of genomic data. Why Nationwide Children's Hospital? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children's Hospital, where Passion Meets Purpose. Here, Everyone Matters. We're 14,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we'll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children's badge what they do for a living. They'll tell you it's More Than a Job. It's a calling. It's a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children's Hospital. A Place to Be Proud Responsibilities PRINCIPAL DUTIES AND RESPONSIBILITIES Our ideal candidate will have experience in computational approaches for genomic data analysis, including bioinformatics, data analytics and machine learning. You will primarily focus on the application of your skills to our research programs that study pediatric cancer, congenital heart defects and cardiovascular diseases, birth defects, and rare genetic diseases in collaboration with our research and clinical faculty. As a Senior Bioinformatics Scientist, you will have the opportunity to develop and drive independent computational genomics research projects, driven by your interests and skills. As we scale genome sequencing to thousands of patients, we are particularly interested in the application of artificial intelligence to the discovery and interpretation of genetic variation relevant to disease. This position is part of a distributed team that on occasion will need to come to the NCH main campus for meetings. The option for remote, hybrid or full-time on-site is available. Qualifications Education • PhD. in Bioinformatics or a related field with a focus on 'Omics'-based bioinformatics preferred • Minimum two years of postdoctoral experience or five years professional experience in computational biology or bioinformatics Responsibilities • Conduct research, development and evaluation of computational approaches to advance our understanding of pediatric disease • Perform next generation sequencing data analysis, interpretation and visualization • Based upon your experience and identifying an area you are passionate about, take a lead role in our translational research protocols or computational genomics research areas • Communicate findings to clinicians and researchers, author journal publications and present at professional meetings • Assist in supervision and training of junior bioinformatics scientists, analysts and trainees at the graduate and postdoctoral level Skills & Attributes • Fluency in programming and scripting languages is required (e.g., R, Python, etc.) and their use in LINUX and cloud computing environments • Expert knowledge of integrative -omics analysis, genomic data analysis (i.e. DNA-Seq, RNA-Seq, ChIP-Seq, etc), data mining, complex data analysis and statistics • Excellent interpersonal and communication skills and the ability to manage multiple projects while maintaining a high level of attention to detail Experience • Confident with the use of bioinformatics tools and databases, approaches to statistical analysis and data visualization methods • Strong understanding of molecular biology and genomics • Experience in algorithm development or machine learning approaches • Proven record of applying or developing computational biology approaches to generate and test new hypotheses • Must be a team player with a history of conducting collaborative and self-directed research within broader goals set by the group MINIMUM PHYSICAL REQUIREMENTS • Sitting - Frequently Talking on phone/in person - Frequently Typing on a keyboard - Constantly Standing/walking - Frequently Physically Active - Occasionally • The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. EOE M/F/Disability/Vet Employment Type: OTHER

Overview We are seeking a Senior Bioinformatics Scientist in the Kidney and Urinary Tract Center at The Abigail Wexner Research Institute at Nationwide Children’s Hospital and they will be responsible for working with laboratory-based scientists and trainees to perform computational and bioinformatic analyses, to provide training, and to develop new computational approaches. The Scientist will... work with all members of the Center, including Principal Investigators, Staff Scientists, technicians, and trainees at all levels. Excellent verbal and written communication skills will be essential as the individual will work collaboratively with scientists on projects that lead to publications and presentations at professional meetings. Flexibility is also important as the Scientist will likely support wide-ranging projects of different scientific focus. Why Nationwide Children's Hospital? Why Nationwide Children’s Hospital The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose. Here, Everyone Matters. We’re 14,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud. Responsibilities What Will You Be Doing? • Analysis and visualization of RNA-seq, ChIP-seq, and other next generation sequencing-derived large data sets • Interface and integrate with other bioinformatic/computational-biology/research informatics teams on campus • Evaluate and integrate community-developed and commercial bioinformatics tools • Develop new computational analytic tools • Manage center resources for storage and analysis of large datasets • Obtain, process, and analyze datasets from outside sources, such as NCBI Small Read Archive and individual labs and assist research teams in uploading to those databases • Take a lead role in our research collaborations to analyze genome sequencing data in order to identify the genetic causes of urinary tract infections and congenital malformations of the kidney and genitourinary tract • Assist with supervision and training of postdocs, fellows, students, and staff, for basic bioinformatic approaches • Author journal publications and present at professional meetings Qualifications What Are We Looking For? Minimum Qualifications • Advanced degree in Bioinformatics, Computational Biology, or Biology, Molecular Biology, etc., with postdoctoral bioinformatic experience • Two + years experience in computational biology or bioinformatics • Experience with UNIX/LINUX, including proficiency in shell scripting • Proficiency in a scripting language, such as Perl or Python • Expert knowledge of core bioinformatics databases and tools, including programs for analysis of scRNAseq such as Seurat, SoupX, Harmony, and Monocle 2 • Exceptionally deep computational understanding and strong programming skills • Excellent verbal and written communication skills will be essential Additional Qualifications • Previous experience in next generation sequencing data analysis highly desirable – particularly analysis of spatial transcriptomic, scRNAseq, and snRNAseq data sets • Knowledge of multiple threading and multi-core processing • Knowledge of statistical/mathematical packages such as R/Bioconductor • Capable of self-directed research within broader goals set by group EOE M/F/Disability/Vet

Job Title: Associate Scientist I (Bioinformatics analyst) Location: North Chicago, IL... Duration: 03+ Months Job Id: ABBVJP00018287 Job Details: Job Description and title: Bioinformatics analyst 3 month contract with possibility of extension We have an exciting contract opportunity for a Bioinformatics analyst/programmer to support the Emerging Technology Group in GRC. Primary responsibility include providing analysis support for running standard pooled CRISPR screening data and differential expression analysis of bulk RNAseq data, and performing standard validation/QC analysis for data generated by the Genome Technology group. If candidate harbors strong skills/interest in programming/software development, there is also a need to refactor code for the CRISPR screening pipeline, and possible development of visualization (Rshiny App) for various type of analysis. Ideal candidate must have strong linux shell coding experience, comfortable in using R to do data analysis, and proficient in Python. If a candidate is comfortable with job submission using high performance computer servers, that would be a plus. What hours and days will this person be working? Typically between 9AM-5PM Central Time. 4. What are the top 5 skills/requirements this person is required have? a. Required Skill 1: Proficient in using R to do basic data analysis (processing, plotting ) b. Required Skill 2: differential expression statistical testing, this is applicable to both bulk RNAseq and CRISPR screening data c. Required Skill 3: Be able to write Python scripts for data processing d. Required Skill 4: Comfortable working in linux/Unix environment, including job submission using High Performance Computer servers e. Required Skill 5: comfortable working with NGS data (mostly Illumina short read technology) 5. What years of experience, education, and/or certification is required? B.S. in Bioinformatics/Biostatistics with 2+ years applicable experience or M.S. in Bioinformatics/Biostatistics. 6. What is a nice to have (but not required) regarding skills, requirements, experience, education, or certification? 1. Ability to develop R packages from existing R code 2. Ability to read Perl code 3. Experience in working with CRISPR data, 4. Experience developing R shiny App for data visualization 7. What is the environment that this person will be working in (i.e. group setting vs individual role)? Group setting. 8. Is any testing required for this role? No 9. Does this position offer the ability to work remotely on a regular basis or is it an on-site role? If remote opportunity exists, what are the options (i.e. 1 day remote, 4 days on-site)? YES, open for discussion. 10. Other notable details about the environment from the hiring manager about this role 11. What positions/background experience do you feel are successful in this role. Be very comfortable working with NGS data (mainly short read technology) , experience working with Fastqs, SAM/BAM files, have interest in coding

Overview Bioinformatics Analyst... Full-time and Benefit Eligible This position is eligible for a $3,500 Sign On Bonus for external candidates. Our team at The Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital is driven to create a future where no child with genetic disease goes undiagnosed and every child with cancer receives optimal treatment based upon their personal genome sequence. Recognizing that the root cause of many childhood diseases can be traced directly to the genome, our research program focuses on the development of novel technologies to analyze the billions of data points with a patient’s genome. We’re looking for a Bioinformatics Analyst to join the IGM Computational Genomics Group who shares our passion to advance the understanding of disease. You will have the opportunity to work collaboratively with a dynamic team of bioinformatics analysts and scientists, advancing our understanding of genetic diseases through the development of novel bioinformatics methods and by providing researchers and clinicians with accurate and timely analysis of complex genomic data. Why Nationwide Children's Hospital? Why Nationwide Children’s Hospital? The moment you walk through our doors, you feel it. When you meet our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it. Welcome to Nationwide Children’s Hospital, Where Passion Meets Purpose. Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission. We’re 14,000 strong. And it takes every one of us to improve the lives of the kids we care for, and the kids around the world we’ll never meet. Kids who live healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud. Responsibilities As a Bioinformatics Analyst you will be providing support for the Genomic Services Laboratory, assisting in multiple aspects of next-generation sequencing data analysis, including the analysis of genomic, transcriptomic and epigenetic data. This position is part of a distributed team that on occasion will need to come to the NCH main campus for meetings. The option for hybrid or full-time on-site is also available. • Support a wide variety of research through next generation sequencing data analysis, interpretation and visualization • Gather requirements, manage data, and run standardized genomic data analysis pipelines • Perform quality assessment, monitor QC metrics and notify laboratory of issues • Deliver and explain analysis results to investigators, prepare reports and figures for presentations and publications as needed • Contribute towards the team and Institute’s goals in research, software development and testing of new bioinformatics methods • Maintain awareness of current literature and evaluate community-developed bioinformatics tools Qualifications Education • Bachelor’s degree in biology, molecular genetics, computer science, bioinformatics or related field. Advanced degree in bioinformatics, computational biology or biostatistics a plus. Skills & Attributes • Experience in a Linux/Unix environment and familiarity with scripting and process automation (Python/Perl, shell) a strong plus • Interest in genomics and bioinformatics, and willingness to learn concepts and terminology from these fields as needed • Excellent interpersonal and communication skills and the ability to manage multiple projects while maintaining a high level of attention to detail Experience • Knowledge of core bioinformatics tools and databases • Basic understanding of molecular biology and genomics • Must be a team player with a history of conducting collaborative research • The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. EOE M/F/Disability/Vet

Research Assistant Member – biostatistics/bioinformatics OverviewOMRF is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. Oklahoma City offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy. OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic. ResponsibilitiesThe Arthritis and Clinical Immunology Research Program is hiring a Research Assistant Member with biostatistics or... bioinformatics training who is ready to start a transitional faculty position in data analytics. This mentored position would progressively develop novel research design and analytic approaches to optimize rigor and outcomes of clinical research, clinical trials and/or trans-omic analyses of complex human autoimmune disease data. Performs a wide variety of analyses, including but not limited to parametric and non-parametric statistics. Evaluates the statistical methods and procedures used to obtain data and to ensure validity, applicability, efficiency, accuracy, reliability and usability of data. Develops statistical analysis plans and eports results of statistical analyses, including information in the form of graphs, charts, and tables. Conveys results for presentations to non-statistical audiences. Analyzes and interprets statistical data and prepares conclusions. Assists with data visualization. Identifies relationships and trends in data, as well as any factors that could affect the results of research. Writes and publishes peer-reviewed manuscripts, presents findings at national/international meetings, and is mentored to write successful grant applications.This is a transitional position for scientists who have completed an exemplary postdoctoral experience or exceptional new graduates who show promise to develop independent projects and attract extramural grant support. Incumbents are characterized by considerable experience, highly distinctive competence, and a demonstrated ability to perform independently. Benchmark Accountabilities: Conducts advanced scientific research with a high degree of independence and innovation that provides significant contributions to the lab and respective program Manages research projects including budget oversight, as well as providing research mentoring for students, trainees, and colleagues while receiving faculty level mentoring appropriate for emerging principal investigators Personally communicates findings orally and prepares at least the first draft of publications and applications Prepares and submits proposals for individual and/or research program project grant support Engages in laboratory wide teamwork and seeks new opportunities for exploration and collaboration Knowledge, Skills and AbilitiesSound knowledge of the principles and practices of scientific theory, research and investigative methods; to possess innate curiosity about data analytics as applied to biologic problems; demonstrates skill in formulating and testing hypotheses; ability to personally design and conduct data analyses; to analyze and summarize data and results; communicates effectively both orally and in writing in order to competently prepare scientific papers and grant proposals; mentors students, trainees, less experienced scientists and other team members in a manner that will guide/direct their work, yet also inspires, encourages and helps develop them with progressive competency with leadership skills QualificationsPh.D. in Biostatistics, Statistics, Bioinformatics, Applied Mathematics, Epidemiology or other relevant area, and/or M.D., or equivalent and typically two years of exemplary postdoctoral experience. Must have the ability to perform data analyses using appropriate coding languages (such as R) or statistical software programs. Must be a team-player with good organizational and communication skills. Must be able to work independently, as well as highly attentive to detail, and dependable. OMRF has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment. Applicants must have received, or be willing to receive, a COVID-19 vaccine by their start date to be considered for employment.To apply, visit https://careers-omrf.icims.com/jobs/1389/research-assistant-member/job?in_iframe=1OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic.jeid-ed09aa3aaaa3f547988980894f19ba8d

Description A research opportunity is available with the High-Performance Integrated Virtual Environment (HIVE) Team within the Office of Biostatistics and Epidemiology (OBE), Center for Biologics Evaluation and Research (CBER), at the Food and Drug Administration (FDA) in Silver Spring, MD... The HIVE Team is seeking a bioinformatics and data analyst for fellowships in Masters and/or Ph.D. training programs. The participant will train under a team of multi-disciplinary scientists and perform bioinformatics data analysis in the rapidly changing environment of next-generation sequencing and other omics technologies. As a result of this training the participant will acquire new skills in NGS quality assessment analysis, genome and transcriptome analysis and improve their software development and communication skills. Under the guidance of a mentor, responsibilities will include: • Assisting researchers' access, analyze, store and transmit NGS data and information, and collaborating effectively • Identify, import and evaluate genomic datasets and pipelines • Develop novel bioinformatic pipelines, scientific algorithms and adopt existing tools • Communication of results and interpretation to a diverse audience, including senior FDA scientists, collaborators, and internal stakeholders This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is Full time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits. Completion of a successful background investigation by the Office of Personnel Management is required for an applicant to be on-boarded at FDA. OPM can complete a background investigation only for individuals, including non-US Citizens, who have resided in the US for a total of three of the past five years. FDA requires ORISE participants to read and sign their FDA Education and Training Agreement within 30 days of his/her start date, setting forth the conditions and expectations for his/her educational appointment at the agency. This agreement covers such topics as the following: • Non-employee nature of the ORISE appointment; • Prohibition on ORISE Fellows performing inherently governmental functions; • Obligation of ORISE Fellows to convey all necessary rights to the FDA regarding intellectual property conceived or first reduced to practice during their fellowship; • The fact that research materials and laboratory notebooks are the property of the FDA; • ORISE fellow's obligation to protect and not to further disclose or use non-public information. Qualifications The qualified candidate should have received a masters or doctoral degree in one of the relevant fields (eg Bioinformatics, Computational Biology). Degree must have been received within the past five years. Preferred Skills: • Scientific background in Bioinformatics, Molecular Biology, Computational Biology or a related field • Experience in either R or Python (or other Scripting languages such as BASH) • Familiarity with diverse NGS analysis tools (eg samtools, bedtools, GATK, BWA, Bowtie, IGV), secondary analysis tools (eg muTect VarScan, VarDict) and statistical or machine learning algorithms (DeSEQ2, clustering, t-SNE) • Familiarity with publicly available data sources (eg TCGA, ENCODE, COSMIC) and annotations methods • Excellent collaborative, verbal and written communication skills

The Bioinformatics Scientist will take lab-generated data and create computational models that allow further manipulation and experimentation, perform incremental analysis required to process large amounts of data generated in a high-throughput Next Generation Sequencing (NGS) laboratory devoted to analysis of genomics data with a focus on long- and short-read sequencing technologies, including... bulk and single-cell analysis. The NGS data analysis will require both strong programming skills and quantitative/statistical analysis. The successful candidate will thrive in a dynamic, fast-paced working environment and contribute directly to our company culture and success. Candidates must have a graduate degree In Bioinformatics, Computational Biology, or related discipline with a minimum of five (5) years' experience in NGS (Illumina) data analysis. Excellent programming skills, including Python and R, along with demonstrated experience with SQL databases, Unix and REST API; additional preference will be given to candidates knowledgeable in HPC, non-SQL databases, cloud computing, long reads and single-cell NGS. Excellent verbal and written communication skills are required. You must be able to work in a team environment that values open and honest communication, embraces challenge, innovation and continuous improvement, works hard and loves to have fun, is fast-paced and displays a can-do attitude. If this is you and you can prove it, you could be a great fit for our team

At Cepheid, we are passionate about improving health care through fast, accurate diagnostic testing. Our mission drives us, every moment of every day, as we develop scalable, groundbreaking solutions to solve the world's most complex health challenges. Our associates are involved in every stage of molecular diagnostics, from ideation to development and delivery of testing advancements that... improve patient outcomes across a range of settings. As a member of our team, you can make an immediate, measurable impact on a global scale, within an environment that fosters career growth and development. Cepheid is proud to work alongside a community of six fellow Danaher Diagnostics companies. Together, we're working at the pace of change on diagnostic tools that address the world's biggest health challenges, driven by knowing that behind every test there is a patient waiting. Learn about the Danaher Business System which makes everything possible. The Staff Bioinformatics Scientist will help drive bioinformatics projects related to the design of highly multiplexed molecular diagnostics through all stages of planning, design, computational verification and empirical validation in collaboration with experimental scientists and other team members. Primary responsibilities include identification of unique nucleic acid sequences and signatures in various organisms and creation of novel, automated methods for design of primers and probes in complex assays. This role involves extensive collaboration with Bioinformatics Engineers, Bioinformaticians, Molecular Biologists, and others at all stages of assay development from planning to commercialization. This position can be based Remotely or relocation assistance will be provided if you'd like to relocate to Sunnyvale, CA. In this role, you will have the opportunity to: • Rapidly prototype novel, innovative algorithms for the design of multiplexed PCR primers and probes compatible with Cepheid's instrumentation and experimental methods in response to both long-term and emerging company needs. • Assist Bioinformatics Engineers in the development of a robust computational pipeline for automated and semi-automated assay design. • Assist in the development of rigorous methodologies for analyzing PCR primer performance data, perform analyses, and communicate results to experimental scientists and others in the company. • Think creatively in a collaborative environment about novel, innovative solutions for difficult assay design problems. • Analyze data and debug results in order to identify avenues for future development and improvement. The essential requirements of the job include: • Master's degree in bioinformatics or a related field with 3+ years of related work experience OR a Doctoral degree with 1+ years of related work experience. • Proficient and hands-on in Python in a Linux environment, preferably including experience implementing and maintaining bioinformatics pipelines. • Proactive self-starter with strong analytical and troubleshooting skills. Able to conduct and plan independent projects with minimal supervision. • Fundamental understanding of PCR, or ability to learn. It would be a plus if you also possess previous experience in: • PCR primer and probe design. • Design and/or analysis of molecular diagnostics assays. Cepheid, a Danaher company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it's a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at danaherbenefitsinfo.com. When you join us, you'll also be joining Danaher's global organization, where 80,000 people wake up every day determined to help our customers win. As an associate, you'll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System tools and the stability of a tested organization. Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes. The EEO posters are available here. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation. If you've ever wondered what's within you, there's no better time to find out